Browsing Master theses by Subject "diabetes"
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Exploring hnf1ba knockout zebrafish mutant as a model for studying MODY5 disease mechanisms in early pancreas development
(Master thesis, 2023-06-02)Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes, characterised by pancreatic beta-cell dysfunction, early onset (before around 25 years of age), and autosomal dominant inheritance. Heterozygous ... -
Investigations of the CEL VNTR by cellular experiments and in silico analyses
(Master thesis, 2023-06-02)Carboxyl ester lipase (CEL) is a digestive enzyme which is secreted by acinar cells in the pancreas and released into the intestines. In addition to the globular domain responsible for lipase activity, CEL contains a ...