• norsk
    • English
  • English 
    • norsk
    • English
  • Login
View Item 
  •   Home
  • Faculty of Medicine
  • Department of Clinical Dentistry
  • Department of Clinical Dentistry
  • View Item
  •   Home
  • Faculty of Medicine
  • Department of Clinical Dentistry
  • Department of Clinical Dentistry
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Enzyme histochemistry of induced heterotopic bone formation in guinea pigs

Nilsen, Rune; Magnusson, Bengt
Journal article
Thumbnail
View/Open
AOB_24.pdf (2.324Mb)
URI
https://hdl.handle.net/1956/2181
Date
1979
Metadata
Show full item record
Collections
  • Department of Clinical Dentistry [544]
Abstract
In an experimental bone induction model in guinea-pigs, large amounts of heterotopic osteiod and bone were found after 21 days. A semiquantiative intrasectional analysis of oxidative and hydrolytic enzyme activities in the reaction zones showed that matrix-producing cells as well as dentine-resorbing cells had acid phosphatise activity. Leucine aminopeptidase activity was lower in dentinoclasts and macrophages than in matrix-producing cells, which may indicate a function of this enzyme in the production of bone matrix. A substrate-specific ATPase, as well as non-specific alkaline phosphatise and acid phosphatise were active in matrix-producing cells. A close relationship between resorbing cells and matrix-producing cells suggested an inductive mechanism during heterotopic bone formation.
Publisher
Pergamon Press

Contact Us | Send Feedback

Privacy policy
DSpace software copyright © 2002-2019  DuraSpace

Service from  Unit
 

 

Browse

ArchiveCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsDocument TypesJournalsThis CollectionBy Issue DateAuthorsTitlesSubjectsDocument TypesJournals

My Account

Login

Statistics

View Usage Statistics

Contact Us | Send Feedback

Privacy policy
DSpace software copyright © 2002-2019  DuraSpace

Service from  Unit