• norsk
    • English
  • norsk 
    • norsk
    • English
  • Logg inn
Vis innførsel 
  •   Hjem
  • Faculty of Psychology
  • Department of Biological and Medical Psychology
  • Department of Biological and Medical Psychology
  • Vis innførsel
  •   Hjem
  • Faculty of Psychology
  • Department of Biological and Medical Psychology
  • Department of Biological and Medical Psychology
  • Vis innførsel
JavaScript is disabled for your browser. Some features of this site may not work without it.

A network module for the perseus software for computational proteomics facilitates proteome interaction graph analysis

Rudolph, Jan Daniel; Cox, Jürgen
Peer reviewed, Journal article
Published version
Thumbnail
Åpne
PDF (3.103Mb)
Permanent lenke
https://hdl.handle.net/1956/21900
Utgivelsesdato
2019-04-01
Metadata
Vis full innførsel
Samlinger
  • Department of Biological and Medical Psychology [324]
Originalversjon
https://doi.org/10.1021/acs.jproteome.8b00927
Sammendrag
Proteomics data analysis strongly benefits from not studying single proteins in isolation but taking their multivariate interdependence into account. We introduce PerseusNet, the new Perseus network module for the biological analysis of proteomics data. Proteomics is commonly used to generate networks, e.g., with affinity purification experiments, but networks are also used to explore proteomics data. PerseusNet supports the biomedical researcher for both modes of data analysis with a multitude of activities. For affinity purification, a volcano-plot-based statistical analysis method for network generation is featured which is scalable to large numbers of baits. For posttranslational modifications of proteins, such as phosphorylation, a collection of dedicated network analysis tools helps in elucidating cellular signaling events. Co-expression network analysis of proteomics data adopts established tools from transcriptome co-expression analysis. PerseusNet is extensible through a plugin architecture in a multi-lingual way, integrating analyses in C#, Python, and R, and is freely available at http://www.perseus-framework.org.
Utgiver
ACS Publications
Tidsskrift
Journal of Proteome Research
Opphavsrett
Copyright 2019 American Chemical Society

Kontakt oss | Gi tilbakemelding

Personvernerklæring
DSpace software copyright © 2002-2019  DuraSpace

Levert av  Unit
 

 

Bla i

Hele arkivetDelarkiv og samlingerUtgivelsesdatoForfattereTitlerEmneordDokumenttyperTidsskrifterDenne samlingenUtgivelsesdatoForfattereTitlerEmneordDokumenttyperTidsskrifter

Min side

Logg inn

Statistikk

Besøksstatistikk

Kontakt oss | Gi tilbakemelding

Personvernerklæring
DSpace software copyright © 2002-2019  DuraSpace

Levert av  Unit