Browsing Sars International Centre for Marine Molecular Biology by Author "Moran, Yehu"
Now showing items 1-4 of 4
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The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella
Sachkova, Maria; Singer, Shir A; Macrander, Jason; Reitzel, Adam M.; Peigneur, Steve; Tytgat, Jan; Moran, Yehu (Journal article; Peer reviewed, 2019-05-27)The cnidarian Nematostella vectensis has become an established lab model, providing unique opportunities for venom evolution research. The Nematostella venom system is multimodal: involving both nematocytes and ectodermal ... -
NvPOU4/Brain3 Functions as a Terminal Selector Gene in the Nervous System of the Cnidarian Nematostella vectensis
Tourniere, Oceane Barbara; Dolan, David William Peter; Richards, Gemma Sian; Sunagar, Kartik; Columbus-Shenkar, Yaara Y; Moran, Yehu; Rentzsch, Fabian (Journal article; Peer reviewed, 2020-03)Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that characterize distinct cell types. Here, we show that, in the sea anemone Nematostella vectensis, NvPOU4 ... -
Some like it hot: population-specific adaptations in venom production to abiotic stressors in a widely distributed cnidarian
Sachkova, Maria; Macrander, Jason; Surm, Joachim M.; Aharoni, Reuven; Menard-Harvey, Shelcie S.; Klock, Amy; Leach, Whitney B.; Reitzel, Adam M.; Moran, Yehu (Journal article; Peer reviewed, 2020-09)Background: In cnidarians, antagonistic interactions with predators and prey are mediated by their venom, whose synthesis may be metabolically expensive. The potentially high cost of venom production has been hypothesized ... -
Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom
Sachkova, Maria; Landau, Morani; Surm, Joachim M.; Macrander, Jason; Singer, Shir A.; Reitzel, Adam M.; Moran, Yehu (Journal article; Peer reviewed, 2020)The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model for characterizing the evolution of genes functioning in venom and nervous systems. Although venom has evolved independently numerous times ...