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Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis

Sasakura, Yasunori; Oogai, Yuichi; Matsuoka, Terumi; Satoh, Nori; Awazu, Satoko
Journal article, Peer reviewed
Published version
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BIOMed_Transposon.pdf (1.904Mb)
URI
https://hdl.handle.net/1956/2671
Date
2007-10-31
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  • Sars International Centre for Marine Molecular Biology [113]
Original version
https://doi.org/10.1186/gb-2007-8-s1-s3
Abstract
Achievement of transposon mediated germline transgenesis in a basal chordate, Ciona intestinalis, is discussed. A Tc1/mariner superfamily transposon, Minos, has excision and transposition activities in Ciona. Minos enables the creation of stable transgenic lines, enhancer detection, and insertional mutagenesis.
Publisher
BioMed Central
Journal
Genome Biology
Copyright
Copyright 2007 BioMed Central Ltd.

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