Blar i Faculty of Mathematics and Natural Sciences på forfatter "Arnesen, Thomas"
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Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases
Grauffel, Cédric; Abboud, Angèle; Liszczak, Glen; Marmorstein, Ronen; Arnesen, Thomas; Reuter, Nathalie (Peer reviewed; Journal article, 2012-12-28)Nt-acetylation is among the most common protein modifications in eukaryotes. Although thought for a long time to protect proteins from degradation, the role of Nt-acetylation is still debated. It is catalyzed by enzymes ... -
Towards a Functional Understanding of Protein NTerminal Acetylation
Arnesen, Thomas (Peer reviewed; Journal article, 2011-05-31)Protein N-terminal acetylation is a major modification of eukaryotic proteins. Its functional implications include regulation of protein–protein interactions and targeting to membranes, as demonstrated by studies of a ... -
X-chromosome variants are associated with aldosterone producing adenomas
Dutta, Ravi Kumar; Larsson, Malin; Arnesen, Thomas; Heie, Anette; Walz, Martin K.; Alesina, Piero; Gimm, Oliver; Söderkvist, Peter (Journal article; Peer reviewed, 2021)Aldosterone-producing adenomas (APAs) are a major cause of primary aldosteronism (PA) and are characterized by constitutively producing aldosterone, which leads to hypertension. Several mutations have been identified in ...