Blar i Faculty of Mathematics and Natural Sciences på tidsskrift "Frontiers in Endocrinology"
Viser treff 1-5 av 5
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eQTLs as causal instruments for the reconstruction of hormone linked gene networks
(Journal article; Peer reviewed, 2022)Hormones act within in highly dynamic systems and much of the phenotypic response to variation in hormone levels is mediated by changes in gene expression. The increase in the number and power of large genetic association ... -
Mathematical Modeling and Simulation Provides Evidence for New Strategies of Ovarian Stimulation
(Journal article; Peer reviewed, 2021)New approaches to ovarian stimulation protocols, such as luteal start, random start or double stimulation, allow for flexibility in ovarian stimulation at different phases of the menstrual cycle. It has been proposed that ... -
Neurohypophysial and paracrine vasopressinergic signaling regulates aquaporin trafficking to hydrate marine teleost oocytes
(Journal article; Peer reviewed, 2023)The dual aquaporin (Aqp1ab1/Aqp1ab2)-mediated hydration of marine teleost eggs, which occurs during oocyte meiosis resumption (maturation), is considered a key adaptation underpinning their evolutionary success in the ... -
Plasma cortisol linked gene networks in hepatic and adipose tissues implicate corticosteroid binding globulin in modulating tissue glucocorticoid action and cardiovascular risk
(Journal article; Peer reviewed, 2023)Genome-wide association meta-analysis (GWAMA) by the Cortisol Network (CORNET) consortium identified genetic variants spanning the SERPINA6/SERPINA1 locus on chromosome 14 associated with morning plasma cortisol, cardiovascular ... -
Role of EPAC in cAMP-mediated actions in adrenocortical cells
(Peer reviewed; Journal article, 2016-06-13)Adrenocorticotropic hormone regulates adrenal steroidogenesis mainly via the intracellular signaling molecule cAMP. The effects of cAMP are principally relayed by activating protein kinase A (PKA) and the more recently ...