Browsing Department of Biological Sciences by Title
Now showing items 1144-1163 of 2487
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The human NAD metabolome: Functions, metabolism and compartmentalization
(Peer reviewed; Journal article, 2015)The metabolism of NAD has emerged as a key regulator of cellular and organismal homeostasis. Being a major component of both bioenergetic and signaling pathways, the molecule is ideally suited to regulate metabolism and ... -
Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis
(Peer reviewed; Journal article, 2014-10-26)Background: The salmon louse, Lepeophtheirus salmonis, is an ectoparasite of salmonids that causes huge economic losses in salmon farming, and has also been causatively linked with declines of wild salmonid populations. ... -
Hypothalamic agrp and pomc mRNA Responses to Gastrointestinal Fullness and Fasting in Atlantic Salmon (Salmo salar, L.)
(Journal article; Peer reviewed, 2020-02-11)The orexigenic agouti-related protein (AgRP) and the anorexigenic pro-opiomelanocortin (POMC) are crucial players in the control of feed intake in vertebrates, yet their role in teleosts has not been fully established. ... -
Hypoxia tolerance and responses to hypoxic stress during heart and skeletal muscle inflammation in Atlantic salmon (Salmo salar)
(Peer reviewed; Journal article, 2017-07-11)Heart and skeletal muscle inflammation (HSMI) is associated with Piscine orthoreovirus (PRV) infection and is an important disease in Atlantic salmon (Salmo salar) aquaculture. Since PRV infects erythrocytes and farmed ... -
Hypoxia tolerance thresholds for post-smolt Atlantic salmon: Dependency of temperature and hypoxia acclimation
(Journal article, 2013-12-05)Atlantic salmon (Salmo salar L.) experience periodic drops in dissolved oxygen (O2) inside aquaculture sea cages. In order to evaluate whether fish function or welfare is compromised during such drops in O2 (termed hypoxia), ... -
Ice-algal carbon supports harp and ringed seal diets in the European Arctic: evidence from fatty acid and stable isotope markers
(Journal article; Peer reviewed, 2021)Sea-ice declines in the European Arctic have led to substantial changes in marine food webs. To better understand the biological implications of these changes, we quantified the contributions of ice-associated and pelagic ... -
Ichthyobodo hippoglossin. sp. (Kinetoplastea: Prokinetoplastida: Ichthyobodonidae fam. nov.), an ectoparasitic flagellate infecting farmed Atlantic halibut Hippoglossus hippoglossus
(Peer reviewed; Journal article, 2007-01-18)Diseased Atlantic halibut Hippoglossus hippoglossus juveniles from a hatchery in western Norway showed gill and skin infections with an Ichthyobodo species. Genus Ichthyobodo contains a single valid species, I. necator, ... -
Ichthyobodo infections on farmed and wild fish. Methods for detection and identification of Ichthyobodo spp.
(Doctoral thesis, 2013-03-01)Ichthyobodosis is an important parasitic disease that has caused severe loss among ornamental and farmed fish world wide for more than a century. The disease is caused by heavy infections on skin and gills by parasitic ... -
Identification and characterisation of novel SNP markers in Atlantic cod: Evidence for directional selection
(Peer reviewed; Journal article, 2008-02-26)Background The Atlantic cod (Gadus morhua) is a groundfish of great economic value in fisheries and an emerging species in aquaculture. Genetic markers are needed to identify wild stocks in order to ensure sustainable ... -
Identification and characterisation of the ecdysone biosynthetic genes neverland, disembodied and shade in the salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae)
(Peer reviewed; Journal article, 2018-02-05)The salmon louse is a marine ectoparasitic copepod on salmonid fishes. Its lifecycle consists of eight developmental stages, each separated by a molt. In crustaceans and insects, molting and reproduction is controlled by ... -
Identification and characterization of a hyperthermophilic GH9 cellulase from the Arctic Mid-Ocean Ridge vent field
(Peer reviewed; Journal article, 2019-09-06)A novel GH9 cellulase (AMOR_GH9A) was discovered by sequence-based mining of a unique metagenomic dataset collected at the Jan Mayen hydrothermal vent field. AMOR_GH9A comprises a signal peptide, a catalytic domain and a ... -
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
(Peer reviewed; Journal article, 2010-07-01)Background The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with ... -
Identification and characterization of the Atlantic salmon peptide transporter 1a
(Journal article; Peer reviewed, 2020)Peptide transporter 1 (PepT1) mediates the uptake of dietary di-/tripeptides in vertebrates. However, in teleost fish gut, more than one PepT1-type transporter might operate, because of teleost-specific whole gen(om)e ... -
Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens
(Journal article; Peer reviewed, 2023)Salmon louse, Lepeophtheirus salmonis, represents major challenge for salmon farming. Current treatments impose welfare issues and are costly, whereas prophylactic measures are unavailable. Two salmon louse heme peroxidases ... -
Identification and Description of the Key Molecular Components of the Egg Strings of the Salmon Louse (Lepeophtheirus salmonis)
(Peer reviewed; Journal article, 2019-12-03)The salmon louse Lepeophtheirus salmonis is a parasite of Atlantic salmon and other salmonids. Every year, it causes high costs for the Norwegian aquaculture industry. While the morphology of the female genital tract has ... -
Identification and genetic characterization of Saprolegnia parasitica, isolated from farmed and wild fish in Finland
(Journal article; Peer reviewed, 2023)Oomycete infections in farmed fish are one of the most significant disease issues in salmonid aquaculture worldwide. In the present study, Saprolegnia spp. in different farmed fish species in Finland were identified, and ... -
Identification and molecular characterization of two acetylcholinesterases from the salmon louse, Lepeophtheirus salmonis
(Peer reviewed; Journal article, 2015-05-04)Acetylcholinesterase (AChE) is an important enzyme in cholinergic synapses. Most arthropods have two genes (ace1 and ace2), but only one encodes the predominant synaptic AChE, the main target for organophosphates. Resistance ... -
Identification of critical enzymes in the salmon louse chitin synthesis pathway as revealed by RNA interference-mediated abrogation of infectivity
(Journal article; Peer reviewed, 2020)Treatment of infestation by the ectoparasite Lepeophtheirus salmonis relies on a small number of chemotherapeutant treatments that currently meet with limited success. Drugs targeting chitin synthesis have been largely ... -
Identification of Epigenetic Modifications Following Treatment with Olanzapine
(Master thesis, 2018-12-19)No chronic disease burdens the world more than psychiatric disorders (Collins et al., 2011), with an estimated 40% of the population in 30 European countries affected in any given year (Insel et al., 2012). Current medical ...