Blar i Department of Biological Sciences på emneord "759929"
Viser treff 1-20 av 61
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A study of autophagy gene expression in autoimmune Addison's disease
(Master thesis, 2022-06-01) -
Actin N-terminal acetylation impacts cell adhesion and invasion
(Master thesis, 2019-12-14) -
Advanced CRISPR-Cas9 techniques for modulation of non-coding disease-associated genetic variants
(Master thesis, 2023-06-02)The search for genetic explanations of individual susceptibility to complex polygenic diseases has greatly intensified in recent years, with GWAS studies having successfully linked several hundred thousand genomic loci to ... -
Antiviral immune responses in lumpfish (Cyclopterus lumpus) - with emphasis on type I interferons
(Master thesis, 2021-06-01) -
BRCA1 promoter methylation: the influence on gene expression and the effect of long term drug treatment
(Master thesis, 2017-07-04)Breast cancer is the most common type of cancer among woman all over the world, with over 1.67 million new cases in 2012. Heritable breast cancer is closely linked to mutations in the tumor suppressor gene BRCA1, with up ... -
Brd4 as a candidate protein for the recognition of histone H3 lysine 27 acetylation
(Master thesis, 2015-06-29)Post-translational modifications (PTMs) of histone tails are associated with the regulation of transcriptional processes. Patterns of histone modifications mark regions of high or low transcriptional activity, and are ... -
Ca^2+-signalling in C. intestinalis notochord cells during embryonic development
(Master thesis, 2018-05-10)C. intestinalis notochord is an essential structure during embryonic development, conveying position and fate information, in addition to serving as a structural support and enabling locomotion during larval stage. Researchers ... -
Characterization of CD4+ T-Cell Subsets and Responses in Lumpfish (Cyclopterus lumpus).
(Master thesis, 2022-06-01) -
Characterization of insertion variants of the carboxyl-ester lipase (CEL) gene - A role in pancreatic disease?
(Master thesis, 2018-06-26)Carboxyl ester lipase (CEL) is a digestive enzyme that is mainly expressed in the acinar cells of the pancreas. The CEL gene is highly polymorphic due to a variable number of tandem repeat (VNTR) region in the last exon. ... -
Characterization of NAA10 mutations in patients exhibiting phenotypes associated with N-terminal acetylation deficiency
(Master thesis, 2018-12-19)Approximately 80% of the proteins found in human cells are acetylated on their N-terminus, either partially or completely, by a group of enzymes called N-terminal acetyltransferases (NATs)^1. To date, seven NATs, NatA-NatF^2–7 ... -
Characterization of Not homeobox genes during development in Nematostella vectensis
(Master thesis, 2021-06-01) -
Characterization of regulatory T cells in Autoimmune Polyendocrine Syndrome type I, a model disease for autoimmunity
(Master thesis, 2018-12-21)The T and B lymphocytes of the adaptive immune system face the challenge of correctly recognizing antigens originating from a vast number of rapidly evolving pathogens, while ignoring those pertaining to the host itself. ... -
Characterization of the CEL-MODY mouse – A new disease model for chronic pancreatitis
(Master thesis, 2020-06-19) -
Characterization of the dopamine receptor genes in salmon louse, Lepeophtheirus Salmonis
(Master thesis, 2016-06-01) -
Characterization of the pregnane X receptor (PXR) from European hake (Merluccius merluccius): cloning, ligand activation, and bioinformatical analyses
(Master thesis, 2022-09-08)As a response to adverse environmental conditions, organisms have throughout evolution generated a collection of gene families and pathways providing protection and repair of damage caused by physical, chemical, and ... -
Early studies on a novel phosphoinositide 3-kinase p110β isoform, and its localisation
(Master thesis, 2020-12-23)Phosphoionositide 3-kinase (PI3K) is a family of enzymes that are part of the PI3K signalling pathway, which is one of the most often altered pathways in human cancer. The PI3K family is divided into three classes, where ... -
Expression and function of the transcription factor Rx in Nematostella vectensis
(Master thesis, 2023-06-02)The development of the central nervous system is highly studied and a comparatively well understood field of neurogenesis. The fundamental aspects of neurogenesis have however mostly been studied in a select few bilaterian ... -
Fat-depot specific differences in adipose tissue inflammation in the setting of obesity and insulin resistance
(Master thesis, 2020-07-01) -
Functional analysis of BRCA1 variants of uncertain significance (VUS)
(Master thesis, 2022-06-01) -
Functional and molecular characterisation of a unique double homozygous variant causing ABCA4-related retinopathy
(Master thesis, 2023-06-02)