Browsing Department of Biological Sciences by Author "Yadetie, Fekadu"
Now showing items 1-16 of 16
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Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars)
Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu; Rauch, Mateusz; Milinski, Ana; Dejaegere, Annick; Stote, Roland H.; Goksøyr, Anders; Karlsen, Odd André (Journal article; Peer reviewed, 2022)Toxicity mediated by per- and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ... -
Bioaccumulation of mercury and transcriptional responses in tusk (Brosme brosme), a deep-water fish from a Norwegian fjord
Olsvik, Pål Asgeir; Mahjour Azad, Atabak; Yadetie, Fekadu (Journal article; Peer reviewed, 2021)High concentrations of mercury (Hg) have been documented in deep-water fish species from some Norwegian fjords. In this study, tusk (Brosme brosme) was sampled from four locations in the innermost parts of Sognefjorden in ... -
Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics
Yadetie, Fekadu; Butcher, Stephen; Førde, Hilde E.; Campsteijn, Coen; Bouquet, Jean-Marie; Karlsen, Odd André; Denoeud, France; Metpally, Raghu; Thompson, Eric M.; Manak, J. Robert; Goksøyr, Anders; Chourrout, Daniel (Peer reviewed; Journal article, 2012-02-02)Background Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene ... -
Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway
Dale, Karina; Müller, Mette Bjørge; Tairova, Zhanna; Khan, Essa Ahsan; Hatlen, Kristin; Grung, Merete; Yadetie, Fekadu; Lille-Langøy, Roger; Blaser, Nello; Skaug, Hans J; Lyche, Jan Ludvig; Arukwe, Augustine; Hylland, Ketil; Karlsen, Odd André; Goksøyr, Anders (Peer reviewed; Journal article, 2019)The aim of this study was to assess whether fish in Kollevåg, a sheltered bay on the western coast of Norway, previously utilized as a waste disposal site, could be affected by environmental contaminants leaking from the ... -
Effects of Agricultural Pesticides in Aquafeeds on Wild Fish Feeding on Leftover Pellets Near Fish Farms
Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc; Goksøyr, Anders; Karlsen, Odd Andre; Yadetie, Fekadu; Sanden, Monica; Kristensen, Torstein (Peer reviewed; Journal article, 2019-09-26)Screening has revealed that modern-day feeds used in Atlantic salmon aquaculture might contain trace amounts of agricultural pesticides. To reach slaughter size, salmon are produced in open net pens in the sea. Uneaten ... -
Environmentally realistic concentrations of chlorinated, brominated, and fluorinated persistent organic pollutants induce the unfolded protein response as a shared stress pathway in the liver of Atlantic cod (Gadus morhua)
Olsvik, Pål Asgeir; Meier, Sonnich; Zhang, Xiaokang; Goksøyr, Anders; Karlsen, Odd André; Yadetie, Fekadu (Journal article; Peer reviewed, 2023)In the North Sea and North Atlantic coastal areas, fish experience relatively high background levels of persistent organic pollutants. This study aimed to compare the mode of action of environmentally relevant concentrations ... -
Establishment of killer whale (Orcinus orca) primary fibroblast cell cultures and their transcriptomic responses to pollutant exposure
Bjørneset, Juni; Blévin, Pierre; Bjørnstad, Pål Marius; Dalmo, Roy Ambli; Goksøyr, Anders; Harju, Mikael; Yadetie, Fekadu; Routti, Heli Anna Irmeli (Journal article; Peer reviewed, 2023)Populations of killer whale (Orcinus orca) contain some of the most polluted animals on Earth. Yet, the knowledge on effects of chemical pollutants is limited in this species. Cell cultures and in vitro exposure experiments ... -
Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod
Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge; Bruheim, Per; Alendal, Guttorm; Brun, Morten; Porte, Cinta; Karlsen, Odd André (Journal article; Peer reviewed, 2023-03-22)Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ... -
Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism
Yadetie, Fekadu; Karlsen, Odd André; Eide, Marta; Hogstrand, Christer; Goksøyr, Anders (Peer reviewed; Journal article, 2014-06-17)Background: Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in animal tissues, its ... -
Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances
Khan, Essa Ahsan; Bertotto, Luisa B.; Dale, Karina; Lille-Langøy, Roger; Yadetie, Fekadu; Karlsen, Odd Andre; Goksøyr, Anders; Schlenk, Daniel; Arukwe, Augustine (Peer reviewed; Journal article, 2019)The dopaminergic effect of PAH and PFAS mixtures, prepared according to environmentally relevant concentrations, has been studied in juvenile female Atlantic cod (Gadus morhua). Benzo[a]pyrene, dibenzothiophene, fluorene, ... -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey; Sørhus, Elin; Myklatun, Lars Eirik; Zhang, Xiaokang; Lie, Kai Kristoffer; Perrichon, Prescilla; Nakken, Charlotte Langeland; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Goksøyr, Anders; Meier, Sonnich; Karlsen, Odd André (Journal article; Peer reviewed, 2022)Photo-enhanced toxicity of crude oil is produced by exposure to ultraviolet (UV) radiation. Atlantic cod (Gadus morhua) embryos were exposed to crude oil with and without UV radiation (290–400 nm) from 3 days post fertilization ... -
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge; Pampanin, Daniela Maria; Gilabert, Alejandra; Zhang, Xiaokang; Tairova, Zhanna; Haarr, Ane; Lille-Langøy, Roger; Lyche, Jan Ludvig; Porte, Cinta; Karlsen, Odd Andre; Goksøyr, Anders (Journal article; Peer reviewed, 2020)The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ... -
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Horvli, Torill; Zhang, Xiaokang; Frøysa, Håvard G; Karlsen, Odd André; Goksøyr, Anders (Journal article; Peer reviewed, 2022)The aim of the present study was to investigate effects of per- and polyfluoroalkyl substances (PFAS), both single compounds and a mixture of these, using precision-cut liver slices (PCLS) from Atlantic cod (Gadus morhua). ... -
Spawning time in adult polar cod (Boreogadus saida) altered by crude oil exposure, independent of food availability
Strople, Leah Catherine; Vieweg, Ireen; Yadetie, Fekadu; Odei, Derrick Kwame; Thorsen, Anders; Karlsen, Odd André; Goksøyr, Anders; Sørensen, Lisbet; Sarno, Antonio; Hansen, Bjørn Henrik; Frantzen, marianne; Hansen, Øyvind J; Puvanendran, Velmurugu; Nahrgang, Jasmine (Journal article; Peer reviewed, 2023)Fish early life stages are well known for their sensitivity to crude oil exposure. However, the effect of crude oil exposure on adults and their gametes during their spawning period is not well studied. Polar cod, a key ... -
Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene
Yadetie, Fekadu; Brun, Nadja Rebecca; Giebichenstein, Julia; Dmoch, Katarzyna; Hylland, Ketil; Borgå, Katrine; Karlsen, Odd André; Goksøyr, Anders (Journal article; Peer reviewed, 2022)Arctic and sub-arctic pelagic organisms can be exposed to effluents and spills from offshore petroleum-related activities and thus it is important to understand how they respond to crude oil related contaminants such as ... -
Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects
Yadetie, Fekadu; Brun, Nadja R; Vieweg, Ireen; Nahrgang, Jasmine; Karlsen, Odd André; Goksøyr, Anders (Journal article; Peer reviewed, 2021)Polar cod (Boreogadus saida) is a key species in the arctic marine ecosystem vulnerable to effects of pollution, particularly from petroleum related activities. To facilitate studying the effects of those pollutants, we ...