Browsing Department of Biological Sciences by Journals "Toxicology and Applied Pharmacology"

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Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently

Lille-Langøy, Roger; Goldstone, Jared; Rusten, Marte; Milnes, Matthew R.; Male, Rune; Stegeman, John J.; Blumberg, Bruce; Goksøyr, Anders (Peer reviewed; Journal article, 2015-04-01)

Background Many persistent organic pollutants (POPs) accumulate readily in polar bears because of their position as apex predators in Arctic food webs. The pregnane X receptor (PXR, formally NR1I2, here proposed to be named ...