Blar i Department of Biological Sciences på emneord "VDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470::Molekylærbiologi: 473"
Viser treff 1-19 av 19
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Application of in vitro transcribed and translated HIV-1 reverse transcriptase and integrase in protein-protein interaction studies
(Master thesis, 2000)Replication of the human immunodeficiency virus (HIV) necessitates the two viral enzymes reverse transcriptase (RT) and integrase (IN). These two proteins are found to associate in a large nucleoprotein complex called the ... -
Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-α-acetyltransferase
(Peer reviewed; Journal article, 2006-04-25)Background: Protein acetylation is increasingly recognized as an important mechanism regulating a variety of cellular functions. Several human protein acetyltransferases have been characterized, most of them catalyzing ... -
Characterization of Nuclear Respiratory Factor 1 using transgenic zebrafish
(Doctoral thesis, 2006-12-01)Nuclear respiratory factor 1 (NRF1) is a transcription factor essential for the embryonic development of vertebrates. The zebrafish mutant nrf is characterized by apoptotic photoreceptor death during embryogenesis followed ... -
Cooperation between the bromodomain and PHD finger of p300 in nucleosome interaction. A study of the contribution of the PHD finger
(Master thesis, 2003-08)The different cells in an organism need to know which genes to be active and which to be inactive. A central mechanism that contributes to regulate gene expression is the organisation of DNA into dense and less dense forms. ... -
Digestive protease activities, growth and feed utilisation in Atlantic salmon (Salmo salar L.)
(Doctoral thesis, 2006-03-03)The specific activities of trypsin and chymotrypsin in the pyloric caeca were investigated in individually labeled Atlantic salmon (Salmo salar L.). Photoperiod (natural or 24 h) and feed protein quality (two levels of ... -
Fish zona radiata (eggshell) protein: A sensitive biomarker for environmental estrogens
(Peer reviewed; Journal article, 1997-04)Environmental estrogens have recently caused great concern because of their ability to mimic natural hormones and influence vital endocrine functions in humans and wildlife. The induction of vitellogenin (Vtg) synthesis ... -
Functional characterisation of three human nicotinamide mononucleotide adenylyltransferases
(Doctoral thesis, 2008-08-25)Nicotinamide adenine dinucleotide, NAD, is an essential redox factor in many, primarily catabolic, hydrogen transfer reactions. While the redox reactions are not accompanied by a net loss of the pyridine nucleotides, NAD+ ... -
Functional Sites in Proteins: analysis and annotation of five nuclear functional sites for the ELM resource
(Master thesis, 2004)Proteins are molecular tools which a cell expresses from specific genes, where the protein has one or several functions. An example of a protein function can be to detect a particular hormone, transporting itself to the ... -
Functional studies of two wild type variants of HIV-1 Tat
(Master thesis, 2003) -
The influence of CXCR4 on Maedi visna virus-induced syncytium formation
(Master thesis, 2001)Maedi visna virus (MVV) is a retrovirus that is member of the Lentivirus genus. MVV infects sheep and goats and causes progressive pneumonia or paralysis, leading to death. Since the discovery of the receptor for Human ... -
Isocitrate dehydrogenase from extremophiles; Molecular adaptations to high temperatures
(Doctoral thesis, 2006-11-30)Life on earth has adapted to a wide variety of environmental conditions, many of which are extreme to us humans. Temperature is one of the most important factors limiting biological activity and survival, but so far, ... -
Long-range transcriptional regulation of vertebrate developmental genes and the evolution of genome architecture
(Doctoral thesis, 2008-09-12)Despite the recent massive progress in production of vertebrate genome sequence data and large-scale efforts to completely annotate the human genome, we still have scant knowledge of the principles that built genomes in ... -
Nervous necrosis virus (NNV) in farmed Norwegian fish species
(Doctoral thesis, 2008-12-05) -
Nodavirus in farmed Atlantic cod Gadus morhua in Norway
(Peer reviewed; Journal article, 2007-09-14)Viral encephalopathy and retinopathy (VER) was diagnosed in 5 to 24 g sized farmed Atlantic cod Gadus morhua kept in sea cages at Parisvatn, Hordaland county, on the west coast of Norway. Moderate mortality (10 to 15%) was ... -
Proteome changes in Atlantic cod (Gadus morhua) exposed to oil and produced water: discovery of biomarker candidates for environmental monitoring
(Doctoral thesis, 2007-09-07)Produced water is the most dominating source of continuous oil discharges to the sea offshore. It contains a wide range of compounds such as alkyl phenols, polyaromatic hydrocarbons (PAHs), heavy metals, carboxylic acids ... -
A sensetive zonagenetic assay for rapid in vivo assessment of estrogenic potency of xenobiotics and mycotoxins
(Peer reviewed; Journal article, 1999-01)Mounting evidence confirms that hepatic biosynthetic processes are essential for female sexual maturation in fish, which is directly controlled by estrogens. These oogenetic events (zonagenesis and vitellogenesis) are ... -
The zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammals
(Peer reviewed; Journal article, 2010-02-11)Background: Aquaporins are integral membrane proteins that facilitate the transport of water and small solutes across cell membranes. These proteins are vital for maintaining water homeostasis in living organisms. In ...