Blar i Department of Informatics på forfatter "Bankier, Sean Alexander"
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eQTLs as causal instruments for the reconstruction of hormone linked gene networks
Bankier, Sean Alexander; Michoel, Tom (Journal article; Peer reviewed, 2022)Hormones act within in highly dynamic systems and much of the phenotypic response to variation in hormone levels is mediated by changes in gene expression. The increase in the number and power of large genetic association ... -
Plasma cortisol linked gene networks in hepatic and adipose tissues implicate corticosteroid binding globulin in modulating tissue glucocorticoid action and cardiovascular risk
Bankier, Sean Alexander; Michoel, Tom (Journal article; Peer reviewed, 2023)Genome-wide association meta-analysis (GWAMA) by the Cortisol Network (CORNET) consortium identified genetic variants spanning the SERPINA6/SERPINA1 locus on chromosome 14 associated with morning plasma cortisol, cardiovascular ...