Blar i Department of Clinical Dentistry på forfatter "Cimpan, Mihaela-Roxana"
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Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models
Buociková, Verona; Longhin, Eleonora Marta; Pilalis, Eleftherios; Mastrokalou, Chara; Miklíková, Svetlana; Cihova, Marina; Poturnayova, Alexandra; Mackova, Katarina; Bábelová, Andrea; Trnkova, Lenka; El Yamani, Naouale; Zheng, Congying; Rios-Mondragon, Ivan; Labudova, Martina; Csaderova, Lucia; Kuracinova, Kristina Mikus; Makovicky, Peter; Kučerová, Lucia; Matuskova, Miroslava; Cimpan, Mihaela-Roxana; Dusinska, Maria; Babal, Pavel; Chatziioannou, Aristotelis; Gábelová, Alena; Rundén-Pran, Elise; Smolkova, Bozena (Journal article; Peer reviewed, 2022)Acquired drug resistance and metastasis in breast cancer (BC) are coupled with epigenetic deregulation of gene expression. Epigenetic drugs, aiming to reverse these aberrant transcriptional patterns and sensitize cancer ... -
Decitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines; the impact of DCK overexpression
Buociková, Verona; Tyciakova, Sylvia; Pilalis, Eleftherios; Mastrokalou, Chara; Urbanova, Maria; Matuskova, Miroslava; Demkova, Lucia; Medova, Veronika; Longhin, Eleonora Marta; Rundén-Pran, Elise; Dusinska, Maria; Rios Mondragon, Ivan; Cimpan, Mihaela-Roxana; Gábelová, Alena; Soltysova, Andrea; Smolkova, Bozena; Chatziioannou, Aristotelis (Journal article; Peer reviewed, 2022)Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors. Although epigenome modulation provides a promising ... -
Predicting intention of Norwegian dental health-care workers to use nanomaterials: An application of the augmented theory of planned behavior
Xenaki, Victoria; Cuida Marthinussen, Ileana Mihaela; Costea, Daniela Elena; Breivik, Kyrre; Lie, Stein Atle; Cimpan, Mihaela-Roxana; Åstrøm, Anne-Kristine N (Journal article; Peer reviewed, 2021)Due to the rapid development of nanotechnology and its integration into dentistry, there is a need for information on the factors influencing the decision of dental health-care workers to use nanomaterials. Based on a ... -
A strategy towards the generation of testable adverse outcome pathways for nanomaterials
Murugadoss, Sivakumar; Vrcek, Ivana Vinkovic; Pem, Barbara; Jagiello, Karolina; Judzinska, Beata; Sosnowska, Anita; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Dusinska, Maria; Cimpan, Mihaela-Roxana; Fessard, Valérie; Hoet, Peter H. (Journal article; Peer reviewed, 2021)Manufactured nanomaterials (NMs) are increasingly used in a wide range of industrial applications leading to a constant increase in the market size of nano-enabled products. The increased production and use of NMs are ...