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Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection
(Journal article; Peer reviewed, 2023)Mitochondrial DNA heteroplasmy samples can shed light on vital developmental and genetic processes shaping mitochondrial DNA populations. The sample means and sample variance of a set of heteroplasmy observations are ... -
Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck
(Journal article; Peer reviewed, 2021)Mitochondrial DNA (mtDNA) and plastid DNA (ptDNA) encode vital bioenergetic apparatus, and mutations in these organelle DNA (oDNA) molecules can be devastating. In the germline of several animals, a genetic “bottleneck” ... -
Axes of alienation: applying an intersectional lens on the social contract during the pandemic response to protect sexual and reproductive rights and health
(Journal article; Peer reviewed, 2020)While economic inequalities have been a key focus of attention through the COVID 19 pandemic, gendered relations of power at every level have undermined health rights of women, girls and gender diverse individuals. Sexual ... -
AXL is a driver of stemness in normal mammary gland and breast cancer
(Journal article; Peer reviewed, 2020)The receptor tyrosine kinase AXL is associated with epithelial plasticity in several solid tumors including breast cancer and AXL-targeting agents are currently in clinical trials. We hypothesized that AXL is a driver of ... -
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
(Journal article; Peer reviewed, 2020)Introduction Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine ... -
AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model
(Journal article; Peer reviewed, 2021)AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ... -
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
(Journal article; Peer reviewed, 2022)Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB), and introduction of a Stk11/Lkb1 (L) mutation into murine lung adenocarcinomas ... -
Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model
(Journal article; Peer reviewed, 2021)Renal fibrosis is a progressive histological manifestation leading to chronic kidney disease (CKD) and associated with mitochondrial dysfunction. In previous work, we showed that Bemcentinib, an Axl receptor tyrosine kinase ... -
Azimuthal correlations of prompt D mesons with charged particles in pp and p–Pb collisions at √sNN=5.02TeV
(Journal article; Peer reviewed, 2020-10-22)The measurement of the azimuthal-correlation function of prompt D mesons with charged particles in pp collisions at s√=5.02 TeV and p–Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The ... -
«Å leve i krysspresset mellom foreldrerollen og kreftsykdommen»- En kvalitativ studie av unge voksne kreftpasienters erfaringer
(Journal article; Peer reviewed, 2021)Kreft i ung, voksen alder (18–35 år) er sjelden. Behandlingen er oftest aggressiv og langvarig med påfølgende fysiske og psykososiale senskader. Vi har imidlertid lite kunnskap om utfordringene unge voksne kreftpasienter ... -
B cells and autoantibodies in AIRE deficiency
(Journal article; Peer reviewed, 2021)Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare but severe monogenetic autoimmune endocrine disease caused by failure of the Autoimmune Regulator (AIRE). AIRE regulates the negative selection of T cells in the ... -
b-Coloring Parameterized by Clique-Width
(Journal article; Peer reviewed, 2021)We provide a polynomial-time algorithm for b-Coloring on graphs of constant clique-width. This unifies and extends nearly all previously known polynomial-time results on graph classes, and answers open questions posed by ... -
b-Coloring Parameterized by Clique-Width
(Journal article; Peer reviewed, 2023)We provide a polynomial-time algorithm for b- Coloring on graphs of constant clique-width. This unifies and extends nearly all previously known polynomial time results on graph classes, and answers open questions posed by ... -
B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study
(Journal article; Peer reviewed, 2023)Background Calcium channel blockers (CCBs) are used for the treatment of cardiovascular disease (CVD), including angina pectoris, and hypertension; however, the effect on survival remains uncertain. CCBs impair fibrinolysis ... -
“Back to Eden”: An explorative qualitative study on traditional medicine use during pregnancy among selected women in Lusaka Province, Zambia
(Journal article; Peer reviewed, 2020)Background and purpose: No qualitative study on traditional medicine use among Zambian pregnant women has ever been conducted. Accordingly, this study was performed to explore the perceptions, motivations and experiences ... -
Back to the basics of polar expeditions: personality hardiness, fear, and nutrition in polar environments
(Journal article; Peer reviewed, 2023)The present paper aims at presenting an overview of findings relating personality hardiness to adaptation to polar environments. Several studies from the Operational Psychology Research group at the University of Bergen ... -
Background removal from global auroral images: Data driven dayglow modelling
(Journal article; Peer reviewed, 2023)Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment. However, the cameras are sensitive not only to auroral emissions produced by precipitating particles, but ... -
Backward evaluation in peer assessment: A scoping review
(Journal article; Peer reviewed, 2021)Implementing backward evaluation as part of the peer assessment process enables students to react to the feedback they receive on their work within one peer assessment activity cycle. The emergence of online peer assessment ... -
Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania
(Journal article; Peer reviewed, 2020)Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ... -
Bacterial contamination of coffee and personal exposure to inhalable dust and endotoxin in primary coffee processing factories in Ethiopia
(Journal article; Peer reviewed, 2023)Introduction and objective: Endotoxins from gram-negative bacteria might be released when the coffee cherries are processed and may cause respiratory health problems among workers in the coffee industry. The relationship ...