Blar i Department of Clinical Medicine på utgivelsesdato
Viser treff 61-80 av 2077
-
Paediatric Ureteroscopy (P-URS) reporting checklist: a new tool to aid studies report the essential items on paediatric ureteroscopy for stone disease
(Journal article, 2023)The burden of urolithiasis in children is increasing and this is mirrored by the number of surgical interventions in the form of ureteroscopy (URS). There exist many challenges in performing this surgery for this special ... -
Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction
(Journal article; Peer reviewed, 2023)We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can induce oral epithelial differentiation of pluripotent stem cells. Mouse embryonic stem cells (ESC) of the feeder-independent cell line ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Journal article; Peer reviewed, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis
(Journal article; Peer reviewed, 2023)Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ... -
The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data
(Journal article; Peer reviewed, 2023)Background This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU). Methods A systematic search identified all clinical trials that ... -
Renal Functional Response-Association With Birth Weight and Kidney Volume
(Journal article; Peer reviewed, 2023)Introduction: Renal functional response (RFR) is the acute increase in glomerular filtration rate (GFR) after a protein load. Low RFR is a marker of single nephron hyperfiltration. Low birth weight (LBW) is associated with ... -
Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery
(Journal article; Peer reviewed, 2023)Background: The overall poor prognosis in pancreatic cancer is related to late clinical detection. Early diagnosis remains a considerable challenge in pancreatic cancer. Unfortunately, the onset of clinical symptoms in ... -
CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
(Journal article; Peer reviewed, 2023)CD47 expressed on tumor cells binds to signal regulatory protein alpha on macrophages, initiating inhibition of phagocytosis. We investigated the relationships between tumor expression of CD47 and CD68 macrophage content, ... -
Changes in epidemiology and care strategies at the Norwegian National Burn Centre over 35 years (1986–2020)
(Journal article; Peer reviewed, 2023)Introduction: We evaluated trends in admissions, % TBSA (total body surface area) burnt, age, and outcomes over a 35-year period at the national burn centre in Norway. Methods: Relevant data were extracted from the ... -
Errors in medicine: punishment versus learning medical adverse events revisited - expanding the frame
(Journal article; Peer reviewed, 2023)Purpose of review : Despite healthcare workers’ best intentions, some patients will suffer harm and even death during their journey through the healthcare system. This represents a major challenge, and many solutions have ... -
POLG genotype influences degree of mitochondrial dysfunction in iPSC derived neural progenitors, but not the parent iPSC or derived glia
(Journal article; Peer reviewed, 2023)Diseases caused by POLG mutations are the most common form of mitochondrial diseases and associated with phenotypes of varying severity. Clinical studies have shown that patients with compound heterozygous POLG mutations ... -
The Norwegian degenerative spondylolisthesis and spinal stenosis (NORDSTEN) study: study overview, organization structure and study population
(Journal article; Peer reviewed, 2023)Purpose To provide an overview of the The Norwegian Degenerative spondylolisthesis and spinal stenosis (NORDSTEN)-study and the organizational structure, and to evaluate the study population. Methods The NORDSTEN is ... -
Prediction of Surgical Outcome in Advanced Ovarian Cancer by Imaging and Laparoscopy: A Narrative Review
(Journal article; Peer reviewed, 2023)Maximal-effort upfront or interval debulking surgery is the recommended approach for advanced-stage ovarian cancer. The role of diagnostic imaging is to provide a systematic and structured report on tumour dissemination ... -
In situ simulation-based team training and its significance for transfer of learning to clinical practice - A qualitative focus group interview study of anaesthesia personnel
(Journal article; Peer reviewed, 2023)Background Anaesthesia personnel are an integral part of an interprofessional operating room-team; hence, team-based training in non-technical skills (NTS) are important in preventing adverse events. Quite a few studies ... -
Fracture-related infection: Prevalence and application of the new consensus definition in a cohort of 1004 surgically treated ankle fractures
(Journal article; Peer reviewed, 2023)Background Surgical treatment of ankle fractures comes with a substantial risk of complications, including infection. An unambiguously definition of fracture-related infections (FRI) has been missing. Recently, FRI has ... -
Symptoms of post-traumatic stress disorder among first aid providers
(Journal article; Peer reviewed, 2023)Background Every year, large numbers of individuals are present or provide first aid in situations involving out-of-hospital cardiac arrest, injuries, or suicides. Little is known about the impact of providing first aid ... -
Investigating the relationship between allocentric spatial working memory and biomarker status in preclinical and prodromal Alzheimer’s disease
(Journal article; Peer reviewed, 2023)The 4 Mountain Test (4MT) is a test of allocentric spatial working memory and has been proposed as an earlier marker of predementia Alzheimer’s disease (AD) than episodic verbal memory. We here compare the 4MT to the CERAD ... -
Why the Norwegian 2021 guideline for basic life support are different
(Journal article; Peer reviewed, 2023) -
Efficient extraction of small microplastic particles from rat feed and feces for quantification
(Journal article; Peer reviewed, 2023)To date, microplastic is ubiquitously encountered in the environment. Studies analyzing microplastic in terrestrial ecosystems, including animal feces and feed, are few. Microplastic quantification method validation and ... -
Local Treatment of Recurrent Renal Cell Carcinoma May Have a Significant Survival Effect Across All Risk-of-recurrence Groups
(Journal article; Peer reviewed, 2023)Background Retrospective comparative studies suggest a survival benefit after complete local treatment of recurrence (LTR) in renal cell carcinoma (RCC), which may be largely due to an indication bias. Objective To ...