Browsing Bergen Open Research Archive by Title
Now showing items 10484-10503 of 34295
-
Expression of biomarkers (p53, transforming growth factor alpha, epidermal growth factor receptor, c-erbB-2/neu and the proliferative cell nuclear antigen) in oropharyngeal squamous cell carcinomas
(Peer reviewed; Journal article, 1999)Using immunohistochemistry, expression of p53, transforming growth factor-alpha (TGF-α), epidermal growth factor receptor (EGFR), c-erbB-2/neu and proliferating cell nuclear antigen (PCNA) was examined in 26 fresh frozen ... -
Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes
(Peer reviewed; Journal article, 2016-07-27)Background: The purpose of this study was to evaluate invasive and metastatic potential of urothelial cancer by investigating differential expression of various clock genes/proteins participating in the 24 h circadian ... -
Expression of ESE-3 Isoforms in Immunogenic and Tolerogenic Human Monocyte-Derived Dendritic Cells
(Peer reviewed; Journal article, 2012-11-19)Dendritic cells (DC) are the only hematopoietic cells expressing the epithelial specific Ets transcription factor ESE-3. Here we analyzed presence and quantity of isoforms ESE-3a, ESE-3b and ESE-3j in various immunogenic ... -
Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters
(Molecular Cancer 5(47), Peer reviewed; Journal article, 2006-10-20)Background: The tumor suppressor gene p53 (TP53) controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory feature of p53 activity. ... -
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study
(Journal article, 2016-05-11)The aim of this study was to identify potential predictive biomarkers in 35 patients with metastatic melanoma treated with anti-angiogenic bevacizumab monotherapy in a clinical phase II study. The immunohistochemical ... -
Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
(Peer reviewed; Journal article, 2017-09)Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as a ... -
Expression of multiple Sox genes through embryonic development in the ctenophore Mnemiopsis leidyi is spatially restricted to zones of cell proliferation
(Journal article; Peer reviewed, 2014-04-24)Background: The Sox genes, a family of transcription factors characterized by the presence of a high mobility group (HMG) box domain, are among the central groups of developmental regulators in the animal kingdom. They are ... -
Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome
(Journal article; Peer reviewed, 2020)Salivary gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by infiltrating immune cells, and may be accompanied by the presence of adipose tissue. ... -
Expression of segment polarity genes in brachiopods supports a non-segmental ancestral role of engrailed for bilaterians
(Journal article; Peer reviewed, 2016-08-26)The diverse and complex developmental mechanisms of segmentation have been more thoroughly studied in arthropods, vertebrates and annelids—distantly related animals considered to be segmented. Far less is known about the ... -
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
(Peer reviewed; Journal article, 2018-08-23)Memory is indispensable for normal cognitive functioning, and the ability to store and retrieve information is central to mental health and disease. The molecular mechanisms underlying complex memory functions are largely ... -
Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas
(Peer reviewed; Journal article, 2008-02-08)Background It has been suggested that a small population of cells with unique self-renewal properties and malignant potential exists in solid tumors. Such "cancer stem cells" have been isolated by flow cytometry, followed ... -
Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma
(Peer reviewed; Journal article, 2011-08-24)Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer ... -
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas
(Peer reviewed; Journal article, 2013-05-15)Background: The differential diagnosis between primary and secondary breast cancers might be difficult, especially in poorly differentiated tumors. Thyroid Transcription Factor-1 (TTF-1) has been regarded as a reliable ... -
Expression of toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome
(Peer reviewed; Journal article, 2015-03-19)Introduction: Sjögren’s syndrome (SS) is a rheumatic autoimmune disease characterized by inflammation of exocrine glands. As autoantibodies are present in a majority of patients, B cells have been suggested to play an ... -
Expression of visual opsins in the retina of Atlantic salmon (Salmo salar L.) during smoltification
(Master thesis, 2020-06-24)Abstract: The visual system of Atlantic salmon is highly adapted to their migratory and dynamic life-history, where the profound transformational process of smoltification is crucial. The retina contain both rod- and cone ... -
Expression of β-Catenin, E-Cadherin, and α-Smooth Muscle Actin in Basal Cell Carcinoma Before Photodynamic Therapy in Non-recurrent and Recurrent Tumors: Exploring the Ability of Predicting Photodynamic Therapy outcome
(Journal article; Peer reviewed, 2023)Photodynamic therapy (PDT) is an effective and cosmetically beneficial treatment of low-risk basal cell carcinomas (BCCs). To optimize PDT response, it is important to correctly select tumors. We sought to find markers ... -
Expression Profiling of Major Histocompatibility and Natural Killer Complex Genes Reveals Candidates for Controlling Risk of Graft versus Host Disease
(Peer reviewed; Journal article, 2011-01-28)Background: The major histocompatibility complex (MHC) is the most important genomic region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic stem cell transplantation. Matching of MHC ... -
Expression, Purification, and Small Molecule Binding to Cysteine Sulfinic Acid Decarboxylase
(Master thesis, 2023-06-01)Cysteine Sulfinic acid decarboxylase (CSAD) is a PLP-dependent enzyme involved in the biosynthesis of taurine. It converts cysteine sulfinic acid (CSA) into hypotaurine. Hypotaurine is later oxidized into taurine, one of ... -
Expressions of governance, risk, and responsibility: Public campaigns in the crisis and risk management of Covid-19 in Denmark, Norway, and Sweden
(Chapter; Peer reviewed, 2023)During the Covid-19 pandemic, public campaigns were an important part of the Scandinavian health authorities’ strategies to combat the spread of the virus. Denmark, Norway, and Sweden had different strategies to manage the ... -
Expressive Creative Overview System (ECHO): a Creativity Support Tool
(Master thesis, 2017-12-19)A creativity support tool called the Expressive Creative Overview (ECHO) system has been developed in this thesis. It has two main functionalities; one which supports artists to organize their creative processes and the ...