Browsing Bergen Open Research Archive by Title
Now showing items 15230-15249 of 34308
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In vitro digestion method to evaluate solubility of dietary zinc, selenium and manganese in salmonid diets
(Journal article; Peer reviewed, 2020)Background The determination of dietary mineral solubility is one of the main steps in the evaluation of their availability for a given species. Methods This study proposed an in vitro digestion method (acidic and ... -
The in vitro effect of cytokine autoantibodies on Th17-differentiation and function
(Master thesis, 2023-06-01) -
In vitro kvalitet og hemostatisk funksjon i kaldlagret CPDA-1 fullblod etter gjentatte temperatursvingninger til 28 °C
(Master thesis, 2021-11-15)Bakgrunn: Blodprodukter blir ofte utsatt for romtemperatur eller høyere i lengre perioder enn tillatt av retningslinjer. Jeg undersøkte om dette førte til målbar effekt på mye brukte kvalitetsparametere og viskoelastisk ... -
In vitro quality and hemostatic function of cold-stored CPDA-1 whole blood after repeated transient exposure to 28°C storage temperature
(Journal article; Peer reviewed, 2022)Background Blood products are frequently exposed to room temperature or higher for longer periods than permitted by policy. We aimed to investigate if this resulted in a measurable effect on common quality parameters and ... -
In vitro quality of cold and delayed cold-stored platelet concentrates from interim platelet units during storage for 21 days
(Journal article; Peer reviewed, 2023)Background and Objectives: Based on previous success using apheresis platelets, we wanted to investigate the in vitro quality and platelet function in continuously cold-stored and delayed cold-stored platelet concentrates ... -
In vitro reconstruction of human junctional and sulcular epithelium
(Journal article, 2012)Background: The aim of this study was to develop and characterize standardized in vitro three-dimensional organotypic models of human junctional epithelium (JE) and sulcular epithelium (SE). Methods Organotypic models were ... -
In vitro study of a selective PI3K inhibitor on brain metastases
(Master thesis, 2020-06-17) -
In vitro suppression of immune responses using monocyte-derived tolerogenic dendritic cells from patients with primary Sjögren's syndrome
(Peer reviewed; Journal article, 2013-09-09)Introduction: Therapeutic vaccination with antigen-specific tolerogenic dendritic cells (tolDC) might become a future option of individualized therapy for patients with autoimmune diseases. In this study, we tested the ... -
In vitro toxicity of filler particles and methacrylates used in dental composite materials. Cytokine release and cell death
(Doctoral thesis, 2013-09-20)Dental polymer-based composite materials are complex materials consisting of several components, the main components being filler particles (inorganic component) and polymer matrix (organic component). The organic component ... -
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways
(Peer reviewed; Journal article, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ... -
In vitro-based Modelling of Relative Biological Effectiveness in Proton Therapy
(Master thesis, 2021-06-14)Many cancer patients can benefit from proton therapy, as the treatment modality have been shown to provide a more conformal irradiation of the target while sparing surrounding healthy tissue, compared to photon therapy. ... -
In vitro-stimulated IL-6 monocyte secretion and in vivo peripheral blood T lymphocyte activation uniquely predicted 15-year survival in patients with head and neck squamous cell carcinoma
(Peer reviewed; Journal article, 2015-06-16)The study was performed in order to determine whether peripheral blood monocyte in vitro function, and lymphocyte in vivo activation at diagnosis, was associated with HPV tumor infection status and 15-year survival in head ... -
In vivo biodistribution of fluorescent nanocolloids intended for drug delivery - Evaluation of PEGylation state and fluorophore incorporation approach.
(Master thesis, 2012-05-31)To move the use of PLGA nanocolloids from laboratories towards the use in humans require careful investigations around pharmacokinetics and biodistributions. The biodistributions of the nanocolloids can be traced through ... -
The in vivo effect of integrin α11-deficiency and PDGFR inhibition in breast cancer
(Master thesis, 2018-10-19)Background: The tumor microenvironment is a major contributor to breast cancer progression. The abnormal composition of the extracellular matrix and its deregulated interactions with stromal cells, which is characterizing ... -
In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism
(Journal article; Peer reviewed, 2020)Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy for improving or curing insulin-dependent diabetes. The transplantation of end-stages differentiating ... -
In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2
(Peer reviewed; Journal article, 2016-03)The aim is to evaluate the effect of modifying poly[(l-lactide)-co-(ε-caprolactone)] scaffolds (PLCL) with nanodiamonds (nDP) or with nDP+physisorbed BMP-2 (nDP+BMP-2) on in vivo host tissue response and degradation. The ... -
In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress
(Peer reviewed; Journal article, 2020)Aim: The loss of insulin‐secreting β‐cells, ultimately characterizing most diabetes forms, demands the development of cell replacement therapies. The common endpoint for all ex vivo strategies is transplantation into ... -
In vivo mapping of tumor microcirculation parameters using dynamic contrast enhanced MR imaging
(Master thesis, 2004)