Browsing Bergen Open Research Archive by Title

Now showing items 20668-20687 of 34308

    • Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial 

      Kreitman, Robert J.; Dearden, Claire; Zinzani, Pier Luigi; Delgado, Julio; Robak, Tadeusz; le Coutre, Philipp; Gjertsen, Bjørn Tore; Troussard, Xavier; Roboz, Gail J.; Karlin, Lionel; Gladstone, Douglas E.; Kuptsova-Clarkson, Nataliya; Liu, Shiyao; Patel, Priti; Rotolo, Federico; Mitry, Emmanuel; Pastan, Ira; Giles, Frank (Journal article; Peer reviewed, 2021)
      Background Moxetumomab pasudotox is a recombinant CD22-targeting immunotoxin. Here, we present the long-term follow-up analysis of the pivotal, multicenter, open-label trial (NCT01829711) of moxetumomab pasudotox in ...

    • Möbius Band Surprise: A Systematic Illusion in Imagery 

      Haugland, Mons Daniel; Pearson, David G.; Ekroll, Vebjørn (Journal article; Peer reviewed, 2021)
      When a Möbius loop is cut along the middle of the band, the result is a single connected loop, yet anecdotal evidence from science demonstrations and the use of this effect in magic tricks suggest that most people are ...

    • MPCC: Strong stability of M-stationary points 

      Rückmann, Jan-Joachim; Hernández Escobar, Daniel; Günzel, Harald (Journal article; Peer reviewed, 2021)
      In this paper we study the class of mathematical programs with complementarity constraints MPCC. Under the Linear Independence constraint qualification MPCC-LICQ we state a topological as well as an equivalent algebraic ...

    • MPFA methods for Richards' equation 

      Moholt, Truls (Master thesis, 2021-11-22)

    • MPT64 antigen detection test improves diagnosis of pediatric extrapulmonary tuberculosis in Mbeya, Tanzania 

      Grønningen, Erlend; Nanyaro, Marywinnie; Sviland, Lisbet; Ngadaya, Esther; Muller, William; Torres, Lisete; Mfinanga, Sayoki; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)
      Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study ...

    • MPT64 antigen detection test improves routine diagnosis of extrapulmonary tuberculosis in a low-resource setting: A study from the tertiary care hospital in Zanzibar 

      Jørstad, Melissa Davidsen; Marijani, Msafiri; Dyrhol-Riise, Anne Ma; Sviland, Lisbeth; Mustafa, Tehmina (Peer reviewed; Journal article, 2018-05-09)
      Background: Extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. An immunochemistry-based MPT64 antigen detection test (MPT64 test) has reported higher sensitivity in the diagnosis of EPTB compared with conventional ...

    • MRI adipose tissue segmentation and quantification in R (RAdipoSeg) 

      Haugen, Christine; Lysne, Vegard; Haldorsen, Ingfrid S.; Tjora, Erling; Gudbrandsen, Oddrun Anita; Sagen, Jørn Vegard; Dankel, Simon N; Mellgren, Gunnar (Journal article; Peer reviewed, 2022-10-08)
      Background: Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be ...

    • MRI characterisation of adult onset alpha-methylacyl-coA racemase deficiency diagnosed by exome sequencing 

      Haugarvoll, Kristoffer; Johansson, Stefan; Tzoulis, Charalampos; Haukanes, Bjørn Ivar; Bredrup, Cecilie; Neckelmann, Gesche; Boman, Helge; Knappskog, Per; Bindoff, Laurence (Peer reviewed; Journal article, 2013-01-03)
      Background: Correct diagnosis is pivotal to understand and treat neurological disease. Herein, we report the diagnostic work-up utilizing exome sequencing and the characterization of clinical features and brain MRI in two ...

    • MRI compatible miniature motor system: Proof of Concept 

      Haugsdal, Rene (Master thesis, 2019-12-19)

    • MRI findings in candidates for lumbar disc prosthesis: reliability and relationship to disability and pain 

      Berg, Linda (Doctoral thesis, 2014-11-21)
      Background and objective: In candidates for lumbar disc prosthesis, limited reliability data exist for magnetic resonance imaging (MRI) findings relevant to planning of treatment and to evaluation of outcome after treatment. ...

    • MRI measures of brain volume and cortical complexity in clinical groups and during development 

      Sandu, Anca-Larisa (Doctoral thesis, 2009-05-07)
      The complex structure of the surface of the brain might elude classical magnetic resonance imaging (MRI) methods of characterization, when it comes to measures of surface irregularities. Such measures may be important when ...

    • MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer 

      Dybvik, Julie Andrea; Fasmer, Kristine Eldevik; Ytre-Hauge, Sigmund; Husby, Jenny Hild Aase; Salvesen, Øyvind; Stefansson, Ingunn Marie; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)
      Objectives To explore the diagnostic accuracy of preoperative magnetic resonance imaging (MRI)-derived tumor measurements for the prediction of histopathological deep (≥ 50%) myometrial invasion (pDMI) and prognostication ...

    • An mri-based radiomic prognostic index predicts poor outcome and specific genetic alterations in endometrial cancer 

      Jacob, Havjin; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Fasmer, Kristine E.; Høivik, Erling Andre; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Integrative tumor characterization linking radiomic profiles to corresponding gene expression profiles has the potential to identify specific genetic alterations based on non-invasive radiomic profiling in cancer. The aim ...

    • MRI-based radiomic signatures for pretreatment prognostication in cervical cancer 

      Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Fasmer, Kristine Eldevik; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Halle, Mari Kyllesø; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2023)
      Background Accurate pretherapeutic prognostication is important for tailoring treatment in cervical cancer (CC). Purpose To investigate whether pretreatment MRI-based radiomic signatures predict disease-specific ...

    • MRnews: Design Explorations into Accessibility and News 

      Tveranger, Fay Pedersen (Master thesis, 2023-06-02)
      Creating accessible technology and content is generally seen as beneficial for all users. This is particularly important when the content has a significant societal impact, such as news stories. To find new and innovative ...

    • MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes 

      Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Journal article; Peer reviewed, 2020-01-16)
      Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy ...

    • MRTF specifies a muscle-like contractile module in Porifera 

      Colgren, Jeffrey John; Nichols, S.A. (Journal article; Peer reviewed, 2022)
      Muscle-based movement is a hallmark of animal biology, but the evolutionary origins of myocytes are unknown. Although believed to lack muscles, sponges (Porifera) are capable of coordinated whole-body contractions that ...

    • msHelse: a Self-Management Mobile Application for Persons with Multiple Sclerosis 

      Tonheim, Aleksander Nygård (Master thesis, 2018-06-15)
      This master thesis presents the msHelse application for patient self-management within the field of Multiple Sclerosis (MS). This Design Science research project went through a user-centred design process that included ...

    • mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis 

      Yu, Xinhua; Koczan, Dirk; Sulonen, Anna-Maija; Akkad, Denis A.; Kroner, Antje; Comabella, Manuel; Costa, Gianna; Corongiu, Daniela; Goertsches, Robert; Camina-Tato, Montserrat; Thiese, Hans-Juergen; Nyland, Harald Inge; Mørk, Sverre; Montalban, Xavier; Rieckmann, Peter; Marrosu, Maria G.; Myhr, Kjell-Morten; Epplen, Joerg T.; Saarela, Sanna; Ibrahim, Saleh M. (Peer reviewed; Journal article, 2008-02-13)
      Background: Mitochondrial DNA (mtDNA) polymorphism is a possible factor contributing to the maternal parent-of-origin effect in multiple sclerosis (MS) susceptibility. Methods and Findings: In order to investigate the role ...

    • MtDNA sequence features associated with 'selfish genomes' predict tissue-specific segregation and reversion 

      Røyrvik, Ellen Christine; Johnston, Iain (Journal article; Peer reviewed, 2020)
      Mitochondrial DNA (mtDNA) encodes cellular machinery vital for cell and organism survival. Mutations, genetic manipulation, and gene therapies may produce cells where different types of mtDNA coexist in admixed populations. ...