Blar i Bergen Open Research Archive på tittel

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    • CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration 

      Kråkenes, Torbjørn; Herdlevær, Ida Ajvazi; Raspotnig, Margrethe; Haugen, Mette; Schubert, Manja; Vedeler, Christian A. (Peer reviewed; Journal article, 2019)
      The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ...

    • CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup 

      Aasebø, Kristine; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur; Edqvist, Per-Henrik; Eide, Geir Egil; Pontén, Fredrik; Pfeiffer, Per; Glimelius, Bengt; Sorbye, Halfdan (Journal article; Peer reviewed, 2020-02-11)
      Background: Survival of metastatic colorectal cancer (mCRC) patients has improved, but mainly for trial patients. New predictive and prognostic biomarkers validated in the general mCRC population are needed. Caudal-type ...

    • Cedant arma togae: Ciceros feilslåtte formulering 

      Oppedal, Stig (Skrifter utgitt av det Norske Institutt i Athen, Chapter, 2003)

    • CEL in pancreatic disease: Do alcohol and smoking have an effect on the CEL-HYB1 protein? 

      Pettersen, Helene Nazmiye (Master thesis, 2020-06-23)

    • Celebrations: sanctuaries and the vestiges of cult activity 

      Hielte-Stavropoulou, Maria; Morris, Christine; Peatfield, Alan; Konsolaki - Yannopoulou, Eleni; Whittaker, Helene; Albers, Gabriele; Wedde, Michael; Voyatzis, Mary E.; Handelman, Don; Des Bouvrie, Synnøve; Thomassen, Einar; Kristoffersen, Siv (Papers of the Norwegian Institute at Athens, Book, 2004)

    • A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation 

      Tadele, Dagim Shiferaw; Robertson, Joseph; Crispin, Richard; Herrera, Carmen; Chlubnová, Markéta; Piechaczyk, Laure Isabelle; Ayuda-Duran, Maria del Pilar; Singh, Sachin Kumar; Gedde-Dahl, Tobias; Fløisand, Yngvar; Skavland, Jørn; Wesche, Jørgen; Gjertsen, Bjørn Tore; Enserink, Jorrit (Journal article; Peer reviewed, 2021)
      Breakpoint Cluster Region-Abelson kinase (BCR–Abl) is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for ...

    • Cell cycle regulation of Oikopleura dioica. A study of the cyclin CDK-complement 

      Øvrebø, Jan Inge (Doctoral thesis, 2014-11-14)
      Regulation of the eukaryotic cell cycle is a fundamental biological process which controls proliferation of all eukaryote cells. Progression through the cell cycle is highly dependent on its core regulators; Cyclins and ...

    • Cell cycle regulatory proteins in oral epithelial dysplasia and oral squamous cell carcinomas from Sudan; Association with Toombak-use 

      Ibrahim, Munna Jaffar M. (Master thesis, 2008)
      In Sudan, oral squamous cell carcinoma (OSCC) has been found to be associated with the use of the Sudanese snuff, locally known as toombak. Expression of the cell cycle regulatory proteins, p21WAF1, p16INK4a and Cyclin D1 ...

    • Cell Death inducing microbial protein phosphatase inhibitors-mechanisms of action 

      Kleppe, Rune; Herfindal, Lars; Døskeland, Stein Ove (Peer reviewed; Journal article, 2015-10-22)
      Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the ...

    • Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics 

      Lechuga-Vieco, Ana Victoria; Latorre-Pellicer, Ana; Johnston, Iain; Prota, Gennaro; Gileadi, Uzi; Justo-Méndez, Raquel; Acín-Pérez, Rebeca; Martínez-De-Mena, Raquel; Fernández-Toro, Jose María; Jimenez-Blasco, Daniel; Mora, Alfonso; Nicolás-Ávila, Jose A.; Santiago, Demetrio J.; Priori, Silvia G.; Bolaños, Juan Pedro; Sabio, Guadalupe; Criado, Luis Miguel; Ruíz-Cabello, Jesús; Cerundolo, Vincenzo; Jones, Nick S.; Enríquez, Jose Antonio (Journal article; Peer reviewed, 2020)
      Heteroplasmy, multiple variants of mitochondrial DNA (mtDNA) in the same cytoplasm, may be naturally generated by mutations but is counteracted by a genetic mtDNA bottleneck during oocyte development. Engineered heteroplasmic ...

    • Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration 

      Yassin, Mohammed Ahmed; Leknes, Knut N.; Pedersen, Torbjørn Østvik; Xing, Zhe; Sun, Yang; Lie, Stein Atle; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2015-11)
      Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone marrow stromal stem cells (BMSCs) density ...

    • Cell size of Antarctic phytoplankton as a biogeochemical condition 

      Hewes, Christopher D. (Peer reviewed; Journal article, 2009)
      Two contrasting high nutrient/low chlorophyll regions having different conditions that control phytoplankton production, and separated by an area of blooming, are found during summer in the vicinity of the South Shetland ...

    • Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial 

      Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Hellem, Sølve; Rojewski, Markus; Gjengedal, Harald; Yassin, Mohammed Ahmed Alamin Yousif; Feng, Xin; Skaale, Siren G; Berge, Trond Inge; Rosén, Annika; Shi, Xieqi; Ahmed, Aymen B; Gjertsen, Bjørn Tore; Schrezenmeier, Hubert; Layrolle, Pierre (Journal article; Peer reviewed, 2018)
      Background Autologous grafting, despite some disadvantages, is still considered the gold standard for reconstruction of maxillofacial bone defects. The aim of this study was to evaluate bone regeneration using bone ...

    • Cell type specificity of neurovascular coupling in cerebral cortex 

      Uhlirova, Hana; Kiliç, Kivilcim; Tian, Peifang; Thunemann, Martin; Desjardins, Michèle; Saisan, Payam A.; Sakadžić, Sava; Ness, Torbjørn Vefferstad; Mateo, Celine; Cheng, Qun; Weldy, Kimberly L.; Razoux, Florence; Vandenberghe, Matthieu; Cremonesi, Jonathan A.; Ferri, Christopher G.L.; Nizar, Krystal; Sridhar, Vishnu B.; Steed, Tyler C.; Abashin, Maxim; Fainman, Yeshaiahu; Masliah, Eliezer; Djurovic, Srdjan; Andreassen, Ole Andreas; Silva, Gabriel A.; Boas, David A.; Kleinfeld, David; Buxton, Richard B.; Einevoll, Gaute; Dale, Anders; Devor, Anna (Peer reviewed; Journal article, 2016-05-31)
      Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation ...

    • Cell-centered finite volume discretizations for deformable porous media 

      Nordbotten, Jan Martin (Peer reviewed; Journal article, 2014-08-11)
      The development of cell-centered finite volume discretizations for deformation is motivated by the desire for a compatible approach with the discretization of fluid flow in deformable porous media. We express the conservation ...

    • CellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation 

      Hodneland, Erlend; Kögel, Tanja; Frei, Dominik M.; Gerdes, Hans-Hermann; Lundervold, Arvid (Peer reviewed; Journal article, 2013-08-09)
      The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, where a manual ...

    • Cellular and environmental dynamics influence species-specific extents of organelle gene retention 

      Garcia Pascual, Belen; Nordbotten, Jan Martin; Johnston, Iain (Journal article; Peer reviewed, 2023)
      Mitochondria and plastids rely on many nuclear-encoded genes, but retain small subsets of the genes they need to function in their own organelle DNA (oDNA). Different species retain different numbers of oDNA genes, and the ...

    • A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian 

      Chrysostomou, Eleni; Flici, Hakima; Gornik, Sebastian G.; Salinas-Saavedra, Miguel; Gahan, James Michael; McMahon, Emma T.; Thompson, Kerry; Hanley, Shirley; Kilcoyne, Michelle; Schnitzler, Christine E.; Gonzalez, Paul; Baxevanis, Andreas D.; Frank, Uri (Journal article; Peer reviewed, 2022)
      Neurogenesis is the generation of neurons from stem cells, a process that is regulated by SoxB transcription factors (TFs) in many animals. Although the roles of these TFs are well understood in bilaterians, how their ...

    • The cellular and molecular mechanisms of the notochord tubulogenesis in the marine invertebrate Ciona intestinalis 

      Deng, Wei (Doctoral thesis, 2013-01-18)
      The biological tube is the fundamental structural design of most internal organs and body systems. Tubulogenesis involves a series of coordinated cellular processes, failure of any of which can cause severe dysfunctions ...

    • Cellular clearance and protein binding partners of pathogenic CEL-HYB 

      Seierstad, Renate Valdersnes (Master thesis, 2022-06-01)
      The CEL gene encodes the digestive enzyme carboxyl ester lipase, which is mainly expressed in the acinar cells of the pancreas. In 2015, our research group discovered a CEL hybrid gene, named CEL-HYB, resulting from ...