Browsing Bergen Open Research Archive by Title
Now showing items 3691-3710 of 34155
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CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
(Journal article; Peer reviewed, 2020)Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ... -
CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model
(Journal article; Peer reviewed, 2020)Background The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of ... -
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
(Peer reviewed; Journal article, 2012-03-21)Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported. Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment in a ... -
CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
(Journal article; Peer reviewed, 2023)CD47 expressed on tumor cells binds to signal regulatory protein alpha on macrophages, initiating inhibition of phagocytosis. We investigated the relationships between tumor expression of CD47 and CD68 macrophage content, ... -
CD64 as a potential biomarker in septic arthritis
(Peer reviewed; Journal article, 2013-06-19)Background Traditional inflammatory markers are generally unhelpful in discerning septic arthritis from inflammatory joint disease due to their lack of specificity. We wished to explore the discriminatory power of the novel ... -
CDC25 inhibition in acute myeloid leukemia - A study of patient heterogeneity and the effects of different inhibitors
(Peer reviewed; Journal article, 2017-03-11)Cell division cycle 25 (CDC25) protein phosphatases regulate cell cycle progression through the activation of cyclin-dependent kinases (CDKs), but they are also involved in chromatin modulation and transcriptional regulation. ... -
CDOM absorption properties of natural water bodies along extreme environmental gradients
(Peer reviewed; Journal article, 2019-09-24)We present absorption properties of colored dissolved organic matter (CDOM) sampled in six different water bodies along extreme altitudinal, latitudinal, and trophic state gradients. Three sites are in Norway: the mesotrophic ... -
CDR2 antigen and Yo antibodies
(Peer reviewed; Journal article, 2011)Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ... -
CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration
(Peer reviewed; Journal article, 2019)The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ... -
CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
(Journal article; Peer reviewed, 2020-02-11)Background: Survival of metastatic colorectal cancer (mCRC) patients has improved, but mainly for trial patients. New predictive and prognostic biomarkers validated in the general mCRC population are needed. Caudal-type ... -
Cedant arma togae: Ciceros feilslåtte formulering
(Skrifter utgitt av det Norske Institutt i Athen, Chapter, 2003) -
CEL in pancreatic disease: Do alcohol and smoking have an effect on the CEL-HYB1 protein?
(Master thesis, 2020-06-23) -
Celebrations: sanctuaries and the vestiges of cult activity
(Papers of the Norwegian Institute at Athens, Book, 2004) -
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
(Journal article; Peer reviewed, 2021)Breakpoint Cluster Region-Abelson kinase (BCR–Abl) is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for ... -
Cell cycle regulation of Oikopleura dioica. A study of the cyclin CDK-complement
(Doctoral thesis, 2014-11-14)Regulation of the eukaryotic cell cycle is a fundamental biological process which controls proliferation of all eukaryote cells. Progression through the cell cycle is highly dependent on its core regulators; Cyclins and ... -
Cell cycle regulatory proteins in oral epithelial dysplasia and oral squamous cell carcinomas from Sudan; Association with Toombak-use
(Master thesis, 2008)In Sudan, oral squamous cell carcinoma (OSCC) has been found to be associated with the use of the Sudanese snuff, locally known as toombak. Expression of the cell cycle regulatory proteins, p21WAF1, p16INK4a and Cyclin D1 ... -
Cell Death inducing microbial protein phosphatase inhibitors-mechanisms of action
(Peer reviewed; Journal article, 2015-10-22)Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the ... -
Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics
(Journal article; Peer reviewed, 2020)Heteroplasmy, multiple variants of mitochondrial DNA (mtDNA) in the same cytoplasm, may be naturally generated by mutations but is counteracted by a genetic mtDNA bottleneck during oocyte development. Engineered heteroplasmic ... -
Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration
(Peer reviewed; Journal article, 2015-11)Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone marrow stromal stem cells (BMSCs) density ... -
Cell size of Antarctic phytoplankton as a biogeochemical condition
(Peer reviewed; Journal article, 2009)Two contrasting high nutrient/low chlorophyll regions having different conditions that control phytoplankton production, and separated by an area of blooming, are found during summer in the vicinity of the South Shetland ...