Blar i Bergen Open Research Archive på tittel
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The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
(Journal article; Peer reviewed, 2021)T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T ... -
Character strengths, life satisfaction and orientations to happiness - a study of the Nordic countries
(Master thesis, 2011-12-14)Health promotion and positive psychology both focus on the positive aspects of health, and share a view in which the prevention of health problems are as important as repairing damage. Whereas much is known about how to ... -
Characterisation and expression analysis of the Atlantic halibut (Hippoglossus hippoglossus L.) cytokines: IL-1β, IL-6, IL-11, IL-12β and IFNγ
(Peer reviewed; Journal article, 2011-06-05)Genes encoding the five Atlantic halibut (Hippoglossus hippoglossus L.) cytokines; interleukin (IL)-1b, IL-6, IL-11b, IL-12bc, and interferon (IFN) c, were cloned and characterised at a molecular level. The genomic ... -
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
(Journal article; Peer reviewed, 2022)Hydroxymethylbilane synthase (HMBS) is the third enzyme involved in haem biosynthesis, in which it catalyses the formation of tetrapyrrole 1-hydroxymethylbilane (HMB). In this process, HMBS binds four consecutive substrate ... -
Characterisation of a Digital Sampling Calorimeter Prototype for Proton Computed Tomography With Electron Beams
(Master thesis, 2020-12-19)Proton CT is a novel imaging modality designed to improve dose planning and treatment monitoring in proton therapy. The precision of the beam of charged particles, like protons, requires accurate diagnostics, to avoid ... -
Characterisation of age and polarity at onset in bipolar disorder
(Journal article; Peer reviewed, 2021)Background Studying phenotypic and genetic characteristics of age at onset (AAO) and polarity at onset (PAO) in bipolar disorder can provide new insights into disease pathology and facilitate the development of screening ... -
Characterisation of extensional faults in carbonate rocks (Suez Rift, Egypt); with particular focus on the role of shale smear
(Master thesis, 2012-04-27)The distribution, composition and flow-properties of fault core and shale smear along faults in carbonate reservoirs is less well understood compared to faults in siliciclastic rocks. This study uses field data to characterize ... -
Characterisation of genomic imbalances in patients with mental retardation
(Doctoral thesis, 2009-03-20)A major cause of mental retardation is chromosomal abnormalities, but due to low sensitivity of conventional chromosomal karyotyping, these abnormalities may stay undetected, and the etiology of the impairment remains ... -
Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes
(Journal article; Peer reviewed, 2023)Aims/hypothesis Correctly diagnosing MODY is important, as individuals with this diagnosis can discontinue insulin injections; however, many people are misdiagnosed. We aimed to develop a robust approach for determining ... -
Characterisation of Immunoglobulin--IgG Responses During Combination Therapy of Chronic Hepatits-C Virus Infection
(Master thesis, 2009-06-02)Current recommended treatment of chronic hepatitis C is the combination of peg interferon and ribavirin. Ribavirin has shown that it poses both direct and indirect action mechanisms against several DNA and RNA viruses. ... -
Characterisation of Leishmania amino acid permease 3 (AAP3) coding sequences and flanking regions as a target of detection and diagnosis of the leishmaniases
(Doctoral thesis, 2020-05-29)The protozoan parasites of Leishmania genus are the etiological agents of the leishmaniases, diseases whose clinical manifestations range from being asymptomatic, self-healing cutaneous lesions, via mutilating muco-cutaneous ... -
Characterisation of Megabenthic Community Structure at the Fåvne Hydrothermal Vent Field, with Implications for Environmental Management of Seabed Mining
(Master thesis, 2023-05-15)There is an increased interest for deep-sea mining in Norwegian waters due to the potential use of minerals in the green shift. However, concerns have been raised regarding the sustainability of such activities. This study ... -
Characterisation of Single Wind Turbine Wakes with Static and Scanning WINTWEX-W LiDAR Data
(Peer reviewed; Journal article, 2015)With further development of LiDAR technology wake measurements by use of LiDAR became of common interest in the wind energy community. To study new measurement strategies of scanning and nacelle LiDARs, in combination with ... -
Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5
(Peer reviewed; Journal article, 2009-03-30)Background: Saxitoxin and its analogues collectively known as the paralytic shellfish toxins (PSTs) are neurotoxic alkaloids and are the cause of the syndrome named paralytic shellfish poisoning. PSTs are produced by a ... -
Characterising Mesoscale Fast Flow Channels in the Polar Cap Ionosphere
(Doctoral thesis, 2021-01-22)The large-scale ionospheric convection that circulates in the high-latitude polar caps was initially assumed to be a smooth, laminar flow. However, it has now come to light that this is an oversimplified understanding of ... -
Characterising the local and intense water cycle during a cold air outbreak in the Nordic Seas
(Journal article; Peer reviewed, 2018)Air masses in marine cold air outbreaks (CAOs) at high latitudes undergo a remarkable diabatic transformation because of the uptake of heat and moisture from the ocean surface, and the formation of precipitation. In this ... -
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
(Journal article; Peer reviewed, 2021)Increased risk-taking is a central component of bipolar disorder (BIP) and is implicated in schizophrenia (SCZ). Risky behaviours, including smoking and alcohol use, are overrepresented in both disorders and associated ... -
Characteristics and fate of patients with rectal cancer not entering a curative-intent treatment pathway: A complete nationwide registry cohort of 3,304 patients
(Journal article; Peer reviewed, 2022)Background: Treatment options for advanced and metastatic rectal cancer have increased during the past decades. However, a considerable proportion of the patients are not eligible for curative treatment, and data on this ... -
Characteristics and Meteorological Environment of Terrestrial Gamma-ray Flashes
(Doctoral thesis, 2021-05-28)This thesis investigates the geographic and meteorological conditions in which Terrestrial Gamma-ray Flashes (TGFs) are produced. TGFs are submillisecond bursts of gamma radiation produced inside thunderclouds in association ...