Blar i Bergen Open Research Archive på forfatter "Gilja, Odd Helge"
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Normal Liver Stiffness Values in Children - A Comparison of Three Different Elastography Methods
Mjelle, Anders Batman; Mulabecirovic, Anesa; Havre, Roald Flesland; Rosendahl, Karen; Juliusson, Petur Benedikt; Olafsdottir, Edda Jonina; Gilja, Odd Helge; Vesterhus, Mette (Peer reviewed; Journal article, 2019-05)Objectives: Noninvasive tests for the evaluation of liver fibrosis are particularly helpful in children to avoid general anesthesia and potential complications of invasive tests. We aimed to establish reference values for ... -
The outcome of primary per oral endoscopic myotomy (POEM) for treatment of achalasia: Norwegian single-center experience with long-term follow-up
Pham, Khanh Do-Cong; Lauritzen, Sigurd; Tjora, Erling; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Assmus, Jörg; Havre, Roald Flesland (Journal article; Peer reviewed, 2022)Background and aims: Per oral endoscopic myotomy (POEM) has become an established treatment for achalasia, but no Scandinavian studies with long-term follow-up exist. This study from a tertiary referral center in Norway ... -
Overlapping of irritable bowel syndrome with erosive esophagitis and the performance of Rome criteria in diagnosing IBS in a clinical setting
El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar (Peer reviewed; Journal article, 2019)Irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD) overlap. It is not clear whether GERD is caused by non‑erosive esophagitis, or erosive esophagitis. The Rome criteria are not widely used for the ... -
Plasma levels of guanylins are reduced in patients with Crohn’s disease
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ... -
Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults
Taraldsen, Victoria; Tomasgard, Sunneva; Rudlang, Margrethe Thune; Gilja, Odd Helge; Vesterhus, Mette; Mjelle, Anders Batman (Journal article; Peer reviewed, 2020)Purpose Ultrasound elastography is a noninvasive method for liver stiffness measurement (LSM) with the aim of reflecting approximate liver fibrosis load. Despite minimal evidence, current guidelines recommend 10 min of ... -
Point-of-care ultrasound of the gastrointestinal tract
Gilja, Odd Helge; Nylund, Kim (Journal article; Peer reviewed, 2023)The widespread use of portable ultrasound scanners has promoted the concept of point of care ultrasound (POCUS), namely “ultrasound performed bedside and interpreted directly by the clinician.” The purpose of this short ... -
Postprandial Symptoms in Patients With Functional Dyspepsia and Irritable Bowel Syndrome: Relations to Ultrasound Measurements and Psychological Factors
Steinsvik, Elisabeth Kjelsvik; Valeur, Jørgen; Hausken, Trygve; Gilja, Odd Helge (Journal article; Peer reviewed, 2020)Background/Aims Dyspeptic symptoms are common in patients with functional gastrointestinal (GI) disorders, and may be related to visceral hypersensitivity. We aim to explore the relation between visceral hypersensitivity ... -
Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ... -
The relation between celiac disease, nonceliac gluten sensitivity and irritable bowel syndrome
El-Salhy, Magdy; Hatlebakk, Jan Gunnar; Gilja, Odd Helge; Hausken, Trygve (Peer reviewed; Journal article, 2015-09-07)Wheat products make a substantial contribution to the dietary intake of many people worldwide. Despite the many beneficial aspects of consuming wheat products, it is also responsible for several diseases such as celiac ... -
Secretin-stimulated ultrasound estimation of pancreatic secretion in cystic fibrosis validated by magnetic resonance imaging
Engjom, Trond; Tjora, Erling; Wathle, Gaute Kjellevold; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Gilja, Odd Helge; Haldorsen, Ingfrid S.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2018-04)Objectives: Secretin-stimulated magnetic resonance imaging (s-MRI) is the best validated radiological modality assessing pancreatic secretion. The purpose of this study was to compare volume output measures from ... -
SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
Kotopoulis, Spiros; Popa, Mihaela-Lucia; Mayoral Safont, Mireia; Murvold, Elsa Thodesen; Haugse, Ragnhild; Langer, Anika; Dimcevski, Georg Gjorgji; Lam, Christina; Bjånes, Tormod Karlsen; Gilja, Odd Helge; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2022)The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ... -
Stomach antral endocrine cells in patients with irritable bowel syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-10)To the best of our knowledge, stomach antral endocrine cells have not previously been investigated in patients with irritable bowel syndrome (IBS). Thus, in the present study, 76 patients with IBS were examined (designated ... -
Study protocol of the Bergen brain-gut-microbiota-axis study: A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome
Berentsen, Birgitte; Nagaraja, Bharath Halandur; Teige, Erica Persson; Lied, Gülen Arslan; Lundervold, Astri; Lundervold, Katarina; Steinsvik, Elisabeth Kjelsvik; Hillestad, Eline Margrete Randulff; Valeur, Jørgen; Brønstad, Ingeborg; Gilja, Odd Helge; Osnes, Berge; Hatlebakk, Jan Gunnar; Haász, Judit; Labus, Jennifer; Gupta, Arpana; Mayer, Emeran; Benitez-Páez, Alfonso; Sanz, Yolanda; Lundervold, Arvid; Hausken, Trygve (Journal article; Peer reviewed, 2020-09)Introduction: Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained gastrointestinal (GI) symptoms, recently described as a disturbance of the brain-gut-microbiota (BGM) axis. To gain a ... -
Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys
Eikrem, Øystein Solberg; Kotopoulis, Spiros; Popa, Mihaela-Lucia; Safont, Mireia Mayoral; Fossan, Kjell Ove; Leh, Sabine; Landolt, Lea; Babickova, Janka; Gudbrandsen, Oddrun Anita; Gilja, Odd Helge; Riedel, Bettina Maria Ingeborg; Schjøtt, Jan Didrik; McCormack, Emmet; Marti, Hans-Peter (Journal article; Peer reviewed, 2021-11-29)The use of ultrasound and microbubble-enhanced drug delivery, commonly referred to as sonoporation, has reached numerous clinical trials and has shown favourable results. Nevertheless, the microbubbles and acoustic path ... -
Ultrasound echo-intensity predicts severe Pancreatic affection in cystic fibrosis patients
Engjom, Trond; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2015-03-24)Background: Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype. Methods: Patients with cystic ... -
Ultrasound imaging for assessing functions of the GI tract
Steinsvik, Elisabeth Kjelsvik; Hatlebakk, Jan Gunnar; Hausken, Trygve; Nylund, Kim; Gilja, Odd Helge (Journal article; Peer reviewed, 2021)Objective: In the following review we outline how ultrasound can be used to measure physiological processes in the gastrointestinal tract. Approach: We have investigated the potential of ultrasound in assessing ... -
Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells
Bjånes, Tormod Karlsen; Kotopoulis, Spiros; Murvold, Elsa Thodesen; Kamceva, Tina; Gjertsen, Bjørn Tore; Gilja, Odd Helge; Schjøtt, Jan; Riedel, Bettina; McCormack, Emmet (Journal article; Peer reviewed, 2020)Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles ... -
What should be known prior to performing EUS?
Dietrich, Christoph F.; Arcidiacono, Paolo Giorgio; Braden, Barbara; Burmeister, Sean; Carrara, Silvia; Cui, Xinwu; Di Leo, Milena; Dong, Yi; Fusaroli, Pietro; Gilja, Odd Helge; Healey, Andrew J.; Hocke, Michael; Hollerbach, Stephan; Garcia, Julio Iglesias; Ignee, André; Jürgensen, Christian; Kahaleh, Michel; Kitano, Masayuki; Kunda, Rastislav; Larghi, Alberto; Möller, Kathleen; Napoleon, Bertrand; Oppong, Kofi W.; Petrone, Maria Chiara; Saftoiu, Adrian; Puri, Rajesh; Sahai, Anand V.; Santo, Erwin; Sharma, Malay; Soweid, Assaad; Sun, Siyu; Teoh, Anthony Yuen Bun; Vilmann, Peter; Jenssen, Christian (Peer reviewed; Journal article, 2019-02-14)Direct referral of patients for EUS – instead of preprocedural consultation with the endosonographer – has become standard practice (like for other endoscopic procedures) as it is time- and cost-effective. To ensure ... -
Wireless motility capsule compared with scintigraphy in the assessment of diabetic gastroparesis
Sangnes, Dag André; Søfteland, Eirik; Bekkelund, Mattis; Frey, Jakub; Biermann, Martin; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2019-12-30)Background: Gastroparesis is a potentially severe late complication of diabetes mellitus. Today, delayed gastric emptying (GE) is mandatory for establishing the diagnosis. In this study, we compared wireless motility capsule ...