Browsing Bergen Open Research Archive by Title
Now showing items 4658-4677 of 35894
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Clinical studies of epidemic influenza and pandemic COVID-19 to improve the chain of patient care: from bedside diagnostics to long-term complications :
(Doctoral thesis, 2022-11-29)Tidlig diagnostikk og rask og målrettet behandling kan forbedre utfallet av influensa og Covid-19 sykdom. Gjennom prospektive, kontrollerte observasjonsstudier har vi vist betydningen av rask diagnostikk for å redusere ... -
Clinical Studies of Vestibular Schwannomas
(Doctoral thesis, 2009-02-27) -
A clinical study of musculoskeletal dysfunction in targets of workplace bullying
(Journal article; Peer reviewed, 2021)Background Workers exposed to bullying often report musculoskeletal symptoms. In this study we have clinically evaluated the prevalence and nature of musculoskeletal dysfunction among a group of workers exposed to bullying ... -
A clinical study of patients with concurrent dizziness and neck pain
(Doctoral thesis, 2020-05-27)Dizziness is a relatively common complaint with a heterogeneous group of patients with several plausible causes. There has long been a controversy regarding the role of the cervical spine in dizziness and balance issues, ... -
Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer
(Journal article; Peer reviewed, 2023)Background: Immune checkpoint inhibitors (ICI) have become first-line treatment for metastatic colorectal cancer (CRC) with deficient mismatch repair (dMMR). Despite the remarkable response reported in preliminary trials, ... -
The clinical use of mechanical insufflation-exsufflation in children with neuromuscular disorders in Europe
(Journal article; Peer reviewed, 2018)Mechanical insufflation-exsufflation (MI-E) is a strategy to treat pulmonary exacerbations in neuromuscular disorders (NMDs). Pediatric guidelines for optimal setting titration of MI-E are lacking and the settings used in ... -
Clinically significant discrepancies between sleep problems assessed by standard clinical tools and actigraphy
(Peer reviewed; Journal article, 2017-10-27)Background: Sleep disturbances are widespread among nursing home (NH) patients and associated with numerous negative consequences. Identifying and treating them should therefore be of high clinical priority. No prior studies ... -
Clinically significant drug–drug interactions involving opioid analgesics used for pain treatment in patients with cancer: a systematic review
(Peer reviewed; Journal article, 2015-09-16)Background: Opioids are the most frequently used drugs to treat pain in cancer patients. In some patients, however, opioids can cause adverse effects and drug–drug interactions. No advice concerning the combination of ... -
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
(Journal article; Peer reviewed, 2021)Detection of tumour-specific circulating cell-free DNA in plasma (ctDNA) fails in a significant number of cases depending on the clinical context. The primary aim was to investigate clinicopathological factors associated ... -
Clinimetric properties of a translated and culturally adapted Norwegian version of the Patient and Observer Scar Assessment Scale for use in clinical practice and research
(Journal article; Peer reviewed, 2021)Purpose To translate and culturally adapt the Patient and Observer Scar Assessment Scale, POSAS, to Norwegian and explore its test-retest, intra- and inter-tester reliability. Methods POSAS was translated into Norwegian ... -
Clinoform systems: Review and dynamic classification scheme for shorelines, subaqueous deltas, shelf edges and continental margins
(Peer reviewed; Journal article, 2018-10)Clinoforms are inclined and normally basinward-dipping horizons developed over a range of spatial and temporal scales in both siliciclastic and carbonatic systems. The study of clinoform successions underpins sequence ... -
Clique-Based Neural Associative Memories
(Doctoral thesis, 2021-11-15)Auto-associative memories store a set of patterns and retrieve them by resorting to a part of their contents. This thesis focuses on developing and extending a type of associative memories relying on a sort of coded neural ... -
Clitellate worms (Annelida) in late-glacial and Holocene sedimentary DNA records from the Polar Urals and northern Norway
(Peer reviewed; Journal article, 2018-11-26)While there are extensive macro‐ and microfossil records of a range of plants and animals from the Quaternary, earthworms and their close relatives amongst annelids are not preserved as fossils and therefore the knowledge ... -
Clock genes and biological rhythms. Effects of psychotropic drugs
(Doctoral thesis, 2012-11-16)The sleep-wake cycle, lipid metabolism and hormone levels are examples of circadian rhythms, which are endogenously generated cycles that reach both maximum and minimum values once in the course of 24 hours. In mammals, ... -
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
(Journal article; Peer reviewed, 2022)We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ... -
Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
(Journal article; Peer reviewed, 2022)Background Subclonal evolution during primary breast cancer treatment is largely unexplored. We aimed to assess the dynamic changes in subclonal composition of treatment-naïve breast cancers during neoadjuvant ... -
Clonal heterogeneity reflected by pi3k-akt-mtor signaling in human acute myeloid leukemia cells and its association with adverse prognosis
(Peer reviewed; Journal article, 2018-09-14)Clonal heterogeneity detected by karyotyping is a biomarker associated with adverse prognosis in acute myeloid leukemia (AML). Constitutive activation of the phosphatidylinositol-3-kinase-Akt-mechanistic target of rapamycin ... -
Cloned and outbred Atlantic salmon display equal parasite dispersion when infected with the salmon louse
(Peer reviewed; Journal article, 2017-11)The salmon louse is an ectoparasitic copepod that infects salmonids in the marine environment. This parasite causes a major economic and biological challenge to the Atlantic salmon farming industry, and efforts to increase ... -
Cloning, expression and purification of Atlantic salmon (Salmo salar, L.) neuroglobin
(Journal article, 2012)Neuroglobin (Ngb) exists only in small amounts in salmon brain. In order to study the protein in more detail salmon neuroglobin (sNgb) was cloned, hetereologously expressed in E.coli and purified. The protein had red color ...