• Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals 

      Brum, Wagner S.; Ashton, Nicholas J.; Simrén, Joel; di Molfetta, Guiglielmo; Karikari, Thomas K.; Benedet, Andrea L.; Zimmer, Eduardo R.; Lantero-Rodriguez, Juan; Montoliu-Gaya, Laia; Jeromin, Andreas; Aarsand, Aasne Karine; Bartlett, William A.; Calle, Pilar Fernández; Coşkun, Abdurrahman; Díaz–Garzón, Jorge; Jonker, Niels; Zetterberg, Henrik; Sandberg, Sverre; Carobene, Anna; Blennow, Kaj (Journal article; Peer reviewed, 2024)
      INTRODUCTION Blood biomarkers have proven useful in Alzheimer's disease (AD) research. However, little is known about their biological variation (BV), which improves the interpretation of individual-level data. METHODS We ...
    • Critical appraisal and meta-analysis of biological variation estimates for kidney related analytes 

      Jonker, Niels; Aslan, Berna; Boned, Beatriz; Marqués-García, Fernando; Ricos, Carmen; Alvarez, Virtudes; Bartlett, William A.; Braga, Federica; Carobene, Anna; Coşkun, Abdurrahman; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Gonzalez-Lao, Elisabet; Minchinela, Joana; Perich, Carmen; Simón, Margarita; Sandberg, Sverre; Aarsand, Aasne Karine (Journal article; Peer reviewed, 2020)
      Objective: Kidney markers are some of the most frequently used laboratory tests in patient care, and correct clinical decision making depends upon knowledge and correct application of biological variation (BV) data. The ...
    • The European Biological Variation Study (EuBIVAS): A summary report 

      Carobene, Anna; Aarsand, Aasne Karine; Bartlett, William A.; Coşkun, Abdurrahman; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Guerra, Elena; Jonker, Niels; Locatelli, Massimo; Plebani, Mario; Sandberg, Sverre; Ceriotti, Ferruccio (Journal article; Peer reviewed, 2022)
      Biological variation (BV) data have many important applications in laboratory medicine. Concerns about quality of published BV data led the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) 1st ...
    • The European Biological Variation Study (EuBIVAS): Biological Variation Data for Coagulation Markers Estimated by a Bayesian Model 

      Aarsand, Aasne K.; Kristoffersen, Ann-Helen; Sandberg, Sverre; Støve, Bård; Coşkun, Abdurrahman; Fernandez-Calle, Pilar; Díaz-Garzón, Jorge; Guerra, Elena; Ceriotti, Ferruccio; Jonker, Niels; Røraas, Thomas; Carobene, Anna (Journal article; Peer reviewed, 2021)
      Background For biological variation (BV) data to be safely used, data must be reliable and relevant to the population in which they are applied. We used samples from the European Biological Variation Study (EuBIVAS) to ...
    • The European Biological Variation Study (EuBIVAS): weekly biological variation of cardiac troponin I estimated by the use of two different high-sensitivity cardiac troponin I assays 

      Ceriotti, Ferruccio; Marco, Jorge Diaz-Garzon; Fernandez-Calle, Pilar; Maregnani, Alessio; Aarsand, Aasne Karine; Coşkun, Abdurrahman; Jonker, Niels; Sandberg, Sverre; Carobene, Anna (Journal article; Peer reviewed, 2020)
      Background Cardiac troponins (cTn) are specific markers for cardiac damage and acute coronary syndromes. The availability of new high-sensitivity assays allows cTn detection in healthy people, thus permitting the estimation ...
    • European Biological Variation Study (EuBIVAS): Within- and between-subject biological variation estimates for serum thyroid biomarkers based on weekly samplings from 91 healthy participants 

      Bottani, Michela; Aarsand, Aasne Karine; Banfi, Giuseppe; Locatelli, Massimo; Coşkun, Abdurrahman; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Sandberg, Sverre; Ceriotti, Ferruccio; Carobene, Anna (Journal article; Peer reviewed, 2022)
      Objectives: Thyroid biomarkers are fundamental for the diagnosis of thyroid disorders and for the monitoring and treatment of patients with these diseases. The knowledge of biological variation (BV) is important to define ...
    • Systematic review and meta-analysis of within-subject and between-subject biological variation estimates of 20 haematological parameters 

      Coskun, Abdurrahman; Braga, Federica; Carobene, Anna; Tejedor Ganduxe, Xavier; Aarsand, Aasne Karine; Fernández-Calle, Pilar; Díaz-Garzón Marco, Jorge; Bartlett, William; Jonker, Niels; Aslan, Berna; Minchinela, Joana; Boned, Beatriz; González-Lao, Elisabet; Marqués-García, Fernándo; Perich, Carmen; Ricós, Carmen; Simón, Margarita; Sandberg, Sverre (Peer reviewed; Journal article, 2020)
      Background: Interpretation of the complete blood count (CBC) parameters requires reliable biological variation (BV) data. The aims of this study were to appraise the quality of publications reporting BV data for CBC ...
    • Within- and between-subject biological variation data for serum zinc, copper and selenium obtained from 68 apparently healthy Turkish subjects 

      Coşkun, Abdurrahman; Carobene, Anna; Aarsand, Aasne K.; Aksungar, Fehime B.; Serteser, Mustafa; Sandberg, Sverre; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Karpuzoglu, Fatma H.; Coskun, Cihan; Klzllkaya, Emine; Fidan, Damla; Jonker, Niels; Ugur, Esra; Unsal, Ibrahim (Journal article; Peer reviewed, 2022)
      Objectives: Trace elements (TrEL) are nutritionally essential components in maintaining health and preventing diseases. There is a lack of reliable biological variation (BV) data for TrELs, required for the diagnosis and ...
    • Within- and between-subject biological variation data for tumor markers based on the European Biological Variation Study 

      Coşkun, Abdurrahman; Aarsand, Aasne Karine; Sandberg, Sverre; Guerra, Elena; Locatelli, Massimo; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Ceriotti, Ferruccio; Jonker, Niels; Bartlett, William A.; Carobene, Anna (Journal article; Peer reviewed, 2022)
      Objectives: Reliable biological variation (BV) data are required for the clinical use of tumor markers in the diagnosis and monitoring of treatment effects in cancer. The European Biological Variation Study (EuBIVAS) was ...