Blar i Bergen Open Research Archive på forfatter "Løvås, Kristian"

Viser treff 1-20 av 23

    • Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism 

      Grytaas, Marianne; Sellevåg, Kjersti; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian; Larsen, Terje H (Peer reviewed; Journal article, 2018-03)
      Background: Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively ...

    • Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism 

      Grytaas, Marianne; Sellevåg, Kjersti; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian; Larsen, Terje H (Peer reviewed; Journal article, 2018-03)
      Background Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. ...

    • Continuous Subcutaneous Hydrocortisone Infusion versus Oral Hydrocortisone Replacement for Treatment of Addison’s Disease: A Randomized Clinical Trial 

      Øksnes, Marianne; Björnsdottir, Sigridur; Isaksson, Magnus; Methlie, Paal; Carlsen, Siri; Nilsen, Roy Miodini; Broman, Jan-Erik; Triebner, Kai; Kämpe, Olle; Hulting, Anna-Lena; Bensing, Sophie; Husebye, Eystein Sverre; Løvås, Kristian (Peer reviewed; Journal article, 2014)
      Context: Conventional glucocorticoid replacement therapy fails to mimic the physiological cortisol rhythm, which may have implications for morbidity and mortality in patients with Addison’s disease. Objective: The objective ...

    • Development of a Disease-Specific Quality of Life Questionnaire in Addison’s Disease 

      Løvås, Kristian; Curran, Suzanne; Øksnes, Marianne; Husebye, Eystein Sverre; Huppert, Felicia A.; Chatterjee, V. Krishna K. (Peer reviewed; Journal article, 2010-02)
      Context: Patients with Addison’s disease reproducibly self-report impairment in specific dimensions of general well-being questionnaires, suggesting particular deficiencies in health-related quality-of-life (HRQoL). ...

    • Diabetisk ketoacidose ved bruk av SGLT2-hemmer – en pasientserie 

      Lejlic, Selma; Holmaas, Gunhild; Løvås, Kristian; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Bakgrunn: Hemmere av natriumglukose-kotransportør 2 (SGLT2-hemmere) benyttes i økende grad ved diabetes type 2. Resultater fra tidligere studier tyder på en økt forekomst av diabetisk ketoacidose ved bruk av disse ...

    • Diagnostic testing of autonomous cortisol secretion in adrenal incidentalomas 

      Ueland, Grethe Åstrøm; Grinde, Thea; Methlie, Paal; Kelp, Oskar; Løvås, Kristian; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2020)
      Objective: Autonomous cortisol secretion (ACS) is a condition with ACTH-independent cortisol overproduction from adrenal incidentalomas (AI) or adrenal hyperplasia. The hypercortisolism is often mild, and most patients ...

    • Efficacy of adrenal venous sampling is increased by point of care cortisol analysis 

      Viste, Kristin; Grytaas, Marianne Aardal; Jørstad, Melissa; Jøssang, Dag Eirik; Høyden, Eivind Næss; Fotland, Solveig Simmenes; Jensen, Dag Kjartan; Løvås, Kristian; Thordarson, Hrafnkell B; Almås, Bjørg; Mellgren, Gunnar (Peer reviewed; Journal article, 2013)
      Primary aldosteronism (PA) is a common cause of secondary hypertension and is caused by unilateral or bilateral adrenal disease. Treatment options depend on whether the disease is lateralized or not, which is preferably ...

    • Epidemiology and health related quality of life in hypoparathyroidism in Norway 

      Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...

    • Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia 

      Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2014)
      In about 95% of cases, congenital adrenal hyperplasia (CAH) is caused by mutations in CYP21A2 gene encoding steroid 21-hydroxylase (21OH). Recently, we have reported four novel CYP21A2 variants in the Norwegian population ...

    • Genome-wide copy number variation (CNV) in patients with autoimmune Addison’s disease 

      Brønstad, Ingeborg; Wolff, Anette S. B.; Løvås, Kristian; Knappskog, Per; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2011-08-18)
      Background: Addison’s disease (AD) is caused by an autoimmune destruction of the adrenal cortex. The pathogenesis is multi-factorial, involving genetic components and hitherto unknown environmental factors. The aim of the ...

    • High cardiac background activity limits 99mTc-MIBI radioguided surgery in aortopulmonary window parathyroid adenomas 

      Schwarzlmüller, Thomas; Brauckhoff, Katrin; Løvås, Kristian; Biermann, Martin; Brauckhoff, Michael (Peer reviewed; Journal article, 2014-04-23)
      Background: Radioguided surgery using 99m-Technetium-methoxyisobutylisonitrile (99mTc-MIBI) has been recommended for the surgical treatment of mediastinal parathyroid adenomas. However, high myocardial 99mTc-MIBI uptake ...

    • Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6 

      Astor, Marianne; Løvås, Kristian; Wolff, Anette Susanne Bøe; Nedrebø, Bjørn Gunnar; Bratland, Eirik; Steen-Johnsen, Jon; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2015)
      Primary hypomagnesemia with secondary hypocalcemia (HSH) is an autosomal recessive disorder characterized by neuromuscular symptoms in infancy due to extremely low levels of serum magnesium and moderate to severe hypocalcemia. ...

    • A longitudinal follow-up of autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Context: Autoimmune polyendocrine syndrome type 1 (APS1) is a childhood-onset monogenic disease defined by the presence of two of the three major components: hypoparathyroidism, primary adrenocortical insufficiency, and ...

    • Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison’s disease 

      Methlie, Paal; Hustad, Simon Steinar; Kellmann, Ralph; Almås, Bjørg; Moter-Erichsen, M; Husebye, ES; Løvås, Kristian (Peer reviewed; Journal article, 2013)
      Objective: Liquid chromatography–tandem mass spectrometry (LC–MS/MS) offers superior analytical specificity compared with immunoassays, but it is not available in many regions and hospitals due to expensive instrumentation ...

    • Novel inflammatory biomarkers in thyroid eye disease 

      Ueland, Hans Olav; Ueland, Grethe Åstrøm; Løvås, Kristian; Breivik, Lars Ertesvåg; Thrane, Alexander Stanley; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2022)
      Purpose: The aim of this study is to identify biochemical inflammatory markers predicting the presence or risk of developing thyroid eye disease (TED) in patients with Graves' disease (GD). Methods: Patients with GD ...

    • Persistent cardiac organ damage in surgically and medically treated primary aldosteronism 

      Aune, Arleen; Gerdts, Eva; Kokorina, Marina Victorovna; Kringeland, Ester Anne; Midtbø, Helga Bergljot; Løvås, Kristian; Grytaas, Marianne (Journal article; Peer reviewed, 2022)
      Objective: We compared persistent cardiac organ damage in patients treated surgically or medically for primary aldosteronism. Methods: Eighty-four patients (age 57 ± 11 years, 27% women) with primary aldosteronism ...

    • Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease 

      Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olof; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne (Journal article; Peer reviewed, 2021)
      Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ...

    • Preclinical cardiac disease in women and men with primary aldosteronism 

      Aune, Arleen; Kokorina, Marina Victorovna; Grytaas, Marianne Aa.; Midtbø, Helga Bergljot; Løvås, Kristian; Gerdts, Eva (Journal article; Peer reviewed, 2021)
      Purpose: We tested the sex-specific associations between primary aldosteronism (PA), left ventricular (LV) hypertrophy and LV systolic myocardial function. Material and methods: Conventional and speckle tracking ...

    • Prevalence, Risk Factors, and Clinical and Biochemical Characteristics of Alemtuzumab-Induced Graves Disease 

      Ueland, Grethe Åstrøm; Ueland, Hans Olav; Stokland, Ann-Elin Meling; Bhan, Alok; Schønberg, Anne; Sollid, Stina Therese; Morgas, Dina Edvarda; Holmøy, Trygve; Lima, Kari; Methlie, Paal; Løvås, Kristian; Torkildsen, Øivind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2024)
      Objective Atypical Graves disease (GD) is a common complication in multiple sclerosis (MS) patients treated with alemtuzumab. We present epidemiological, clinical, and biochemical characteristics of alemtuzumab-induced ...

    • Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases 

      Grønning, Kaja; Sharma, Archana; Mastroianni, Maria Adele; Karlsson, Bo Daniel; Husebye, Eystein Sverre; Løvås, Kristian; Nermoen, Ingrid (Journal article; Peer reviewed, 2020-03)
      Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report ...