• Acoustic pharyngometry - A new method to facilitate oral appliance therapy 

      Opsahl, Ulrik Leidland; Berge, Morten Eirik; Lehmann, Sverre; Bjorvatn, Bjørn; Opsahl, Per; Johansson, Anders (Journal article; Peer reviewed, 2021)
      Background There is lack of reliable and accurate methods to predict treatment outcomes of oral appliance (OA) treatment. Acoustic pharyngometry (AP) is a non-invasive technique to evaluate the volume and minimal ...
    • Association of Excessive Sleepiness, Pathological Fatigue, Depression, and Anxiety With Different Severity Levels of Obstructive Sleep Apnea 

      Mjelle, Karin Elisabeth Sundt; Lehmann, Sverre; Saxvig, Ingvild W.; Gulati, Shashi; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2022-03-31)
      Objective: The aim of this study was to investigate possible associations between obstructive sleep apnea and fatigue. This naturally led to considering the association between OSA and excessive sleepiness, depression, and ...
    • Characterization of Patients in the International Severe Asthma Registry with High Steroid Exposure Who Did or Did Not Initiate Biologic Therapy 

      Chen, Wenjia; Sadatsafavi, Mohsen; Tran, Trung N.; Murray, Ruth B.; Wong, Chong Boon Nigel; Ali, Nasloon; Ariti, Cono; Gil, Esther Garcia; Newell, Anthony; Alacqua, Marianna; Al-Ahmad, Mona; Altraja, Alan; Al-Lehebi, Riyad; Bhutani, Mohit; Bjermer, Leif; Bjerrum, Anne Sofie; Bourdin, Arnaud; Bulathsinhala, Lakmini; von Bülow, Anna; Busby, John; Canonica, Giorgio Walter; Carter, Victoria; Christoff, George C.; Cosio, Borja G.; Costello, Richard W.; Fitzgerald, J. Mark; Fonseca, João A.; Ha Yoo, Kwang; Heaney, Liam G.; Heffler, Enrico; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Iwanaga, Takashi; Jackson, David J.; Jones, Rupert C.; Koh, Mariko Siyue; Kuna, Piotr; Larenas-Linnemann, Désirée; Lehmann, Sverre; Lehtimäki, Lauri A.; Lyu, Juntao; Mahboub, Bassam; Maspero, Jorge; Menzies-Gow, Andrew N.; Sirena, Concetta; Papadopoulos, Nikolaos; Papaioannou, Andriana I.; De Llano, Luis Pérez; Perng, Diahn-Warng; Peters, Matthew; Pfeffer, Paul E.; Porsbjerg, Celeste M.; Popov, Todor A.; Rhee, Chin Kook; Salvi, Sundeep; Taillé, Camille; Taube, Christian; Torres-Duque, Carlos A.; Ulrik, Charlotte S.; Won Ra, Seung; Wang, Eileen; Wechsler, Michael E.; Price, David B. (Journal article; Peer reviewed, 2022)
      Background: Many severe asthma patients with high oral corticosteroid exposure (HOCS) often do not initiate biologics despite being eligible. This study aimed to compare the characteristics of severe asthma patients with ...
    • Clinical information predicting severe obstructive sleep apnea: A cross-sectional study of patients waiting for sleep diagnostics 

      Jonassen, Trygve Müller; Bjorvatn, Bjørn; Saxvig, Ingvild W.; Eagan, Tomas Mikal Lind; Lehmann, Sverre (Journal article; Peer reviewed, 2022)
      Introduction Obstructive sleep apnea (OSA) is highly prevalent with serious health consequences. Demand for diagnostic studies is high, in many countries exceeding capacity. Purpose The objective of this cross-sectional ...
    • Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both 

      Pfeffer, Paul E.; Ali, Nasloon; Murray, Ruth; Ulrik, Charlotte; Tran, Trung N.; Maspero, Jorge; Peters, Matthew; Christoff, George C.; Sadatsafavi, Mohsen; Torres-Duque, Carlos A.; Altraja, Alan; Lehtimäki, Lauri; Papadopoulos, Nikolaos G.; Salvi, Sundeep; Costello, Richard W.; Cushen, Breda; Heffler, Enrico; Iwanaga, Takashi; Al-Ahmad, Mona; Larenas-Linnemann, Désirée; Kuna, Piotr; Fonseca, João A; Al-Lehebi, Riyad; Rhee, Chin Kook; Perez-de-Llano, Luis; Perng Steve, Diahn-Warng; Mahboub, Bassam; Wang, Eileen; Goh, Celine; Lyu, Juntao; Newell, Anthony; Alacqua, Marianna; Belevskiy, Andrey S.; Bhutani, Mohit; Bjermer, Leif Hilding; Bjornsdottir, Unnur; Bourdin, Arnaud; Bulow, Anna von; Busby, John; Canonica, Giorgio Walter; Cosio, Borja G.; Dorscheid, Delbert R.; Muñoz-Esquerre, Mariana; FitzGerald, J. Mark; Gil, Esther Garcia; Gibson, Peter G.; Heaney, Liam G.; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Jackson, David J.; Koh, Mariko Siyue; Ko, Hsin-Kuo Bruce; Lee, Jae Ha; Lehmann, Sverre; Chaves Loureiro, Cláudia; Lúðvíksdóttir, Dóra; Menzies-Gow, Andrew N.; Mitchell, Patrick; Papaioannou, Andriana I.; Popov, Todor A.; Porsbjerg, Celeste M.; Salameh, Laila; Sirena, Concetta; Taillé, Camille; Taube, Christian; Tohda, Yuji; Wechsler, Michael E.; Price, David B. (Journal article; Peer reviewed, 2023)
      Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients ...
    • Complications and discomfort after research bronchoscopy in the MicroCOPD study 

      Leiten, Elise Orvedal; Eagan, Tomas Mikal; Martinsen, Einar Marius Hjellestad; Nordeide, Eli; Husebø, Gunnar; Knudsen, Kristel Svalland; Lehmann, Sverre; Svanes, Øistein; Bakke, Per S.; Nielsen, Rune (Journal article; Peer reviewed, 2020)
      Background: Data on discomfort and complications from research bronchoscopy in chronic obstructive pulmonary disease (COPD) and asthma is limited. We present complications and discomfort occurring within a week after ...
    • Effect of Continuous Positive Airway Pressure on Symptoms and Prevalence of Insomnia in Patients With Obstructive Sleep Apnea: A Longitudinal Study 

      Lundetræ, Ragnhild Stokke; Saxvig, Ingvild W.; Aurlien, Harald; Lehmann, Sverre; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2021)
      Objective: Obstructive sleep apnea (OSA) and insomnia are the two most common sleep disorders. Continuous positive airway pressure (CPAP) is considered first-line treatment for OSA. In the present study, we assess the ...
    • Effect of continuous positive airway pressure on symptoms of anxiety and depression in patients with obstructive sleep apnea 

      Lundetræ, Ragnhild Stokke; Saxvig, Ingvild W.; Lehmann, Sverre; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2020)
      Purpose The objective was to assess the effect of continuous positive airway pressure (CPAP) on symptoms of anxiety and depression in patients with obstructive sleep apnea (OSA). We hypothesized a decrease in symptoms at ...
    • Factors associated with change in health-related quality of life among individuals treated with long-term mechanical ventilation, a 6-year follow-up study 

      Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini; Natvig, Gerd Karin (Peer reviewed; Journal article, 2018-03)
      Aims: To examine changes and explanatory variables for changes in health-related quality of life in patients treated with long-term mechanical ventilation over a 6-year period. Background: Long-term mechanical ventilation ...
    • Health-related quality of life as predictor for mortality in patients treated with long-term mechanical ventilation 

      Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini; Natvig, Gerd Karin (Peer reviewed; Journal article, 2019-01-11)
      Background The Severe Respiratory Insufficiency (SRI) questionnaire is a specific measure of health-related quality of life (HRQoL) in patients treated with long-term mechanical ventilation (LTMV). The aim of the present ...
    • Impact of Inititing Biologics in Patients With Severe Asthma on Long-term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry 

      Chen, Wenjia; Tran, Trung N.; Sadatsafavi, Mohsen; Murray, Ruth; Wong, Nigel Chong Boon; Ali, Nasloon; Ariti, Con; Bulathsinhala, Lakmini; Gil, Esther Garcia; FitzGerald, J. Mark; Alacqua, Marianna; Al-Ahmad, Mona; Altraja, Alan; Al-Lehebi, Riyad; Bhutani, Mohit; Bjermer, Leif Hilding; Bjerrum, Anne-Sofie; Bourdin, Arnaud; von Bülow, Anna; Busby, John; Canonica, Giorgio Walter; Carter, Victoria; Christoff, George C.; Cosio, Borja G.; Costello, Richard W.; Fonseca, João A.; Gibson, Peter G.; Yoo, Kwang-Ha; Heaney, Liam G.; Heffler, Enrico; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Iwanaga, Takashi; Jackson, David J.; Jones, Rupert C.; Koh, Mariko Siyue; Kuna, Piotr; Larenas-Linnemann, Désirée; Lehmann, Sverre; Lehtimäki, Lauri; Lyu, Juntao; Mahboub, Bassam; Maspero, Jorge; Menzies-Gow, Andrew N.; Newell, Anthony; Sirena, Concetta; Papadopoulos, Nikolaos G.; Papaioannou, Andriana I.; Perez-de-Llano, Luis; Perng (Steve), Diahn-Warng; Peters, Matthew; Pfeffer, Paul E.; Porsbjerg, Celeste M.; Popov, Todor A.; Rhee, Chin Kook; Salvi, Sundeep; Taillé, Camille; Taube, Christian; Torres-Duque, Carlos A.; Ulrik, Charlotte; Ra, Seung-Won; Wang, Eileen; Wechsler, Michael E.; Price, David B. (Journal article; Peer reviewed, 2023)
      Background Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. Objective To examine ...
    • The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease 

      Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune; Tangedal, Solveig; Haaland, Ingvild; Hiemstra, Pieter S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022)
      Background The lower airways microbiome and host immune response in chronic pulmonary diseases are incompletely understood. We aimed to investigate possible microbiome characteristics and key antimicrobial peptides and ...
    • The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis 

      Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune; Tangedal, Solveig; Paytuví-Gallart, Andreu; Sanseverino, Walter; Martinsen, Einar Marius Hjellestad; Hiemstra, Pieter S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022-10-19)
      Background: The role of the pulmonary microbiome in sarcoidosis is unknown. The objectives of this study were the following: (1) examine whether the pulmonary fungal and bacterial microbiota differed in patients with ...
    • Motivation and response rates in bronchoscopy studies 

      Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Leiten, Elise Orvedal; Nordeide, Eli; Bakke, Per S.; Lehmann, Sverre; Nielsen, Rune (Peer reviewed; Journal article, 2019-05-02)
      Background Bronchoscopy is frequently used to sample the lower airways in lung microbiome studies. Despite being a safe procedure, it is associated with discomfort that may result in reservations regarding participation ...
    • No effect of a self-help book for insomnia in patients with obstructive sleep apnea and comorbid chronic insomnia – a randomized controlled trial. 

      Bjorvatn, Bjørn; Berge, Thomas; Lehmann, Sverre; Pallesen, Ståle; Saxvig, Ingvild W. (Peer reviewed; Journal article, 2018-11-29)
      Objective: To compare the effects of a self-help book for insomnia to that of sleep hygiene advice in a randomized controlled trial with follow-up after about 3 months among patients who were diagnosed with obstructive ...
    • Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP 

      Gjerde, Kjersti; Lehmann, Sverre; Berge, Morten Eirik; Johansson, Ann-Katrin Gerd; Johansson, Anders (Peer reviewed; Journal article, 2015-12-27)
      The aim of this retrospective study was to evaluate the effect of individually adjusted custom-made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep ...
    • A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability 

      Aardal, Marit Elisabeth; Svendsen, Lene Løvendahl; Lehmann, Sverre; Eagan, Tomas Mikal; Haaland, Ingvild (Peer reviewed; Journal article, 2017-10-10)
      Objective: The aim of this pilot study was to compare spirometric values obtained with different types of spirometers, spirometers of same type, and repeated measurements with the same spirometer in a pulmonary function ...
    • Prevalence and impact of exercise-induced laryngeal obstruction in asthma: a study protocol for a cross-sectional and longitudinal study 

      Rogde, Åse Johnsen; Lehmann, Sverre; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Hufthammer, Karl Ove; Kvidaland, Haakon Kristian; Vollsæter, Maria; Andersen, Tiina Maarit (Journal article; Peer reviewed, 2023)
      Introduction Exercise-induced laryngeal obstruction (EILO) and exercise-induced asthma can cause troublesome respiratory symptoms that can be difficult to distinguish between. Further, there is now a growing appreciation ...
    • Prevalence of parasomnias in patients with obstructive sleep apnea. A registry-based cross-sectional study 

      Lundetræ, Ragnhild S.; Saxvig, Ingvild W.; Pallesen, Ståle; Aurlien, Harald; Lehmann, Sverre; Bjorvatn, Bjørn (Peer reviewed; Journal article, 2018-07-05)
      Objective: To assess the prevalence of parasomnias in relation to presence and severity of obstructive sleep apnea (OSA). We hypothesized higher parasomnia prevalence with higher OSA severity. Methods: The sample comprised ...
    • Prevalence of several somatic diseases depends on the presence and severity of obstructive sleep apnea 

      Tveit, Ragnhild L.; Lehmann, Sverre; Bjorvatn, Bjørn (Peer reviewed; Journal article, 2018-02-23)
      Study objectives: The objective was to investigate the prevalence of heart attack, angina pectoris, stroke, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, asthma and obesity in relation to the ...