• Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7 

      Zhao, Lin; Wang, Han; Liu, Sijia; Xi, Tao; Wang, Liyuan; Li, Yang; Chen, Lu; Jianping, Ruan; Liang, Xiao (Journal article; Peer reviewed, 2022)
      Excessive fluoride affects ameloblast differentiation and tooth development. The fate of fluorinated ameloblasts is determined by multiple signaling pathways in response to a range of stimuli. Both autophagy and apoptosis ...
    • MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment 

      Zhao, Lin; Su, Jiali; Liu, Sijia; Li, Yang; Xi, Tao; Ruan, Jianping; Liang, Xiao; Huang, Ruizhe (Journal article; Peer reviewed, 2021)
      Dental fluorosis is characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. Excess fluoride could have effects on the ERK signaling, which is essential for the ...
    • Melatonin enhances proliferation and modulates differentiation of neural stem cells via autophagy in hyperglycemia 

      Li, Haoyuan; Zhang, Yanming; Liu, Shangming; Li, Fengpeng; Wang, Benlin; Wang, Jianjie; Cao, Lanfang; Xia, Tongliang; Yao, Qingyu; Chen, Haijun; Zhang, Yulin; Zhu, Xiaodong; Li, Yang; Li, Gang; Wang, Jian; Li, Xingang; Ni, Shilei (Journal article; Peer reviewed, 2019-01)
      Dysfunction of neural stem cells (NSCs) has been linked to fetal neuropathy, one of the most devastating complications of gestational diabetes. Several studies have demonstrated that melatonin (Mel) exerted neuroprotective ...