Browsing Research centres and projects by Journals "BMC Genomics"

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MicroRNAs and essential components of the microRNA processing machinery are not encoded in the genome of the ctenophore Mnemiopsis leidyi

Maxwell, Evan K.; Ryan, Joseph F.; Schnitzler, Christine E.; Browne, William E.; Baxevanis, Andreas D. (Journal article; Peer reviewed, 2012-12-20)

Background: MicroRNAs play a vital role in the regulation of gene expression and have been identified in every animal with a sequenced genome examined thus far, except for the placozoan Trichoplax. The genomic repertoires ...
Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR

Danks, Gemma Barbara; Galbiati, Heloisa; Raasholm, Martina; Torres Cleuren, Yamila Nicole; Valen, Eivind; Navratilova, Pavla; Thompson, Eric (Journal article; Peer reviewed, 2019)

Background: In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic. Results: We ...