Browsing Department of Informatics by Author "Alcorn, Melissa R"

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    • Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network 

      Torres Cleuren, Yamila Nicole; Ewe, Chee Kiang; Chipman, Kyle C; Mears, Emily R; Wood, Cricket G; Al-Alami, Coco Emma Alma; Alcorn, Melissa R; Turner, Thomas L; Joshi, Pradeep M; Snell, Russell G; Rothman, Joel H (Peer reviewed; Journal article, 2019-08-15)
      Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, ...