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dc.contributor.authorMathelier, Anthonyeng
dc.contributor.authorZhao, Xiaobeieng
dc.contributor.authorZhang, Allen W.eng
dc.contributor.authorParcy, Françoiseng
dc.contributor.authorWorsley-Hunt, Rebeccaeng
dc.contributor.authorArenillas, David J.eng
dc.contributor.authorBuchman, Soranaeng
dc.contributor.authorChen, Chih-yueng
dc.contributor.authorChou, Aliceeng
dc.contributor.authorIenasescu, Hanseng
dc.contributor.authorLim, Jonathaneng
dc.contributor.authorShyr, Caspereng
dc.contributor.authorTan, Geeng
dc.contributor.authorZhou, Michelleeng
dc.contributor.authorLenhard, Boriseng
dc.contributor.authorSandelin, Albineng
dc.contributor.authorWasserman, Wyeth W.eng
dc.description.abstractJASPAR ( is the largest open-access database of matrix-based nucleotide profiles describing the binding preference of transcription factors from multiple species. The fifth major release greatly expands the heart of JASPAR—the JASPAR CORE subcollection, which contains curated, non-redundant profiles—with 135 new curated profiles (74 in vertebrates, 8 in Drosophila melanogaster, 10 in Caenorhabditis elegans and 43 in Arabidopsis thaliana; a 30% increase in total) and 43 older updated profiles (36 in vertebrates, 3 in D. melanogaster and 4 in A. thaliana; a 9% update in total). The new and updated profiles are mainly derived from published chromatin immunoprecipitation-seq experimental datasets. In addition, the web interface has been enhanced with advanced capabilities in browsing, searching and subsetting. Finally, the new JASPAR release is accompanied by a new BioPython package, a new R tool package and a new R/Bioconductor data package to facilitate access for both manual and automated methods.en_US
dc.publisherOxford University Pressen_US
dc.rightsAttribution CC BY-NCeng
dc.titleJASPAR 2014: An extensively expanded and updated open-access database of transcription factor binding profilesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2014 The Authorsen_US
dc.source.journalNucleic Acids Research
dc.subject.nsiVDP::Matematikk og naturvitenskap: 400::Basale biofag: 470::Bioinformatikk: 475
dc.subject.nsiVDP::Mathematics and natural scienses: 400::Basic biosciences: 470::Bioinformatics: 475

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