• Alterations in auditory brain stem response distinguish occasional and constant tinnitus 

      Edvall, Niklas K.; Mehraei, Golbarg; Claeson, Martin; Lazar, Andra; Bulla, Jan; Leineweber, Constanze; Uhlén, Inger; Canlon, Barbara; Cederroth, Christopher R. (Journal article; Peer reviewed, 2022)
      BACKGROUND. The heterogeneity of tinnitus is thought to underlie the lack of objective diagnostic measures. METHODS. Longitudinal data from 20,349 participants of the Swedish Longitudinal Occupational Survey of Health ...
    • Association between Hyperacusis and Tinnitus 

      Cederroth, Christopher R; Lugo, Alessandra; Edvall, Niklas K.; Lazar, Andra; Lopez-Escamez, Jose Antonio; Bulla, Jan; Uhlen, Inger; Hoare, Darek J.; Baguley, David M.; Canlon, Barbara; Gallus, Silvano (Journal article; Peer reviewed, 2020-07)
      Many individuals with tinnitus report experiencing hyperacusis (enhanced sensitivity to sounds). However, estimates of the association between hyperacusis and tinnitus is lacking. Here, we investigate this relationship in ...
    • The genetic vulnerability to cisplatin ototoxicity: a systematic review 

      Tserga, Evangelia; Nandwani, Tara; Edvall, Niklas K; Bulla, Jan; Patel, Poulam; Canlon, Barbara; Cederroth, Christopher R; Baguley, David M (Peer reviewed; Journal article, 2019-03-05)
      Ototoxicity is one of the major side-effects of platinum-based chemotherapy, in particular cisplatin (cis-diammine dichloroplatinum II). To our knowledge, no systematic review has previously provided a quantitative summary ...
    • Impact of temporomandibular joint complaints on tinnitus-related distress 

      Edvall, Niklas K; Gunan, Edis; Genitsaridi, Eleni; Lazar, Andra; Mehraei, Golbarg; Billing, Mattias; Tullberg, Marie; Bulla, Jan; Whitton, Jonathon; Canlon, Barbara; Hall, Deborah A; Cederroth, Christopher R (Peer reviewed; Journal article, 2019-08-22)
      There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, ...
    • Relationship between headaches and tinnitus in a Swedish study 

      Lugo, Alessandra; Edvall, Niklas K.; Lazar, Andra; Mehraei, Golbarg; Lopez-Escamez, Jose Antonio; Bulla, Jan; Uhlen, Inger; Canlon, Barbara; Gallus, Silvano; Cederroth, Christopher R (Journal article; Peer reviewed, 2020-05)
      The heterogeneity of tinnitus is likely accounting for the lack of effective treatment approaches. Headaches have been related to tinnitus, yet little is known on how headaches impact tinnitus. We use cross-sectional data ...
    • Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus 

      Cederroth, Christopher R.; Hong, Mun-Gwan; Freydin, Maxim B.; Edvall, Niklas K.; Trpchevska, Natalia; Jarach, Carlotta; Schlee, Winfried; Schwenk, Jochen M.; Lopez-Escamez, Jose-Antonio; Gallus, Silvano; Canlon, Barbara; Bulla, Jan; Williams, Frances M. K. (Journal article; Peer reviewed, 2023)
      Background and Objective Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins. ...
    • Sexual dimorphism in the familial aggregation of tinnitus 

      Trpchevska, Natalia; Bulla, Jan; Prada Hellberg, Matilda; Edvall, Niklas K.; Lazar, Andra; Mehraei, Golbarg; Uhlen, Inger; Schlee, Winfried; Canlon, Barbara; Gallus, Silvano; Lopez-Escamez, Jose Antonio; Cederroth, Christopher R (Journal article; Peer reviewed, 2020-11)
      Twin and adoption studies point towards a genetic contribution to tinnitus; however, how the genetic risk applies to different forms of tinnitus is poorly understood. Here, we perform a familial aggregation study and ...
    • Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus 

      Gallego-Martinez, Alvaro; Escalera-Balsera, Alba; Trpchevska, Natalia; Robles-Bolivar, Paula; Roman-Naranjo, Pablo; Frejo, Lidia; Perez-Carpena, Patricia; Bulla, Jan; Gallus, Silvano; Canlon, Barbara; Cederroth, Christopher R.; Lopez-Escamez, Jose A. (Journal article; Peer reviewed, 2022)
      Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structural variants ...