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dc.contributor.authorTischer, Christinaen_US
dc.contributor.authorZock, Jan-Paulen_US
dc.contributor.authorValkonen, Mariaen_US
dc.contributor.authorDoekes, Gerten_US
dc.contributor.authorGuerra, Stefanoen_US
dc.contributor.authorHeederick, Dicken_US
dc.contributor.authorJarvis, Deborahen_US
dc.contributor.authorNorbäck, Danen_US
dc.contributor.authorOlivieri, Marioen_US
dc.contributor.authorSunyer, Jordien_US
dc.contributor.authorSvanes, Cecilieen_US
dc.contributor.authorTäubel, Martinen_US
dc.contributor.authorThiering, Elisabethen_US
dc.contributor.authorVerlato, Guiseppeen_US
dc.contributor.authorHyvärinen, Anneen_US
dc.contributor.authorHeinrich, Joachimen_US
dc.PublishedBMC Pulmonary Medicine 2015, 15:48eng
dc.description.abstractBackground Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess predictors of microbial agents in mattress dust throughout Europe and to investigate associations between microbial exposures, home characteristics and respiratory health. Methods Seven different fungal and bacterial parameters were assessed in mattress dust from 956 adult ECRHS II participants in addition to interview based home characteristics. Associations between microbial parameters and the asthma score and lung function were examined using mixed negative binomial regression and linear mixed models, respectively. Results Indoor dampness and pet keeping were significant predictors for higher microbial agent concentrations in mattress dust. Current mould and condensation in the bedroom were significantly associated with lung function decline and current mould at home was positively associated with the asthma score. Higher concentrations of muramic acid were associated with higher mean ratios of the asthma score (aMR 1.37, 95%CI 1.17-1.61). There was no evidence for any association between fungal and bacterial components and lung function. Conclusion Indoor dampness was associated with microbial levels in mattress dust which in turn was positively associated with asthma symptoms.en_US
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.titlePredictors of microbial agents in dust and respiratory health in the Ecrhsen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright Tischer et al.; licensee BioMed Central. 2015
dc.subject.nsiVDP::Medisinske fag: 700::Helsefag: 800::Yrkesmedisin: 809
dc.subject.nsiVDP::Midical sciences: 700::Health sciences: 800::Occupational health: 809
dc.subject.nsiVDP::Medisinske Fag: 700en_US

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