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    • DNA from resin-embedded organisms: Past, present and future 

      Peris, David; Janssen, Kathrin; Barthel, H. Jonas; Bierbaum, Gabriele; Delclòs, Xavier; Peñalver, Enrique; Solórzano-Kraemer, Mónica M.; Jordal, Bjarte Henry; Rust, Jes (Journal article; Peer reviewed, 2020)
      Past claims have been made for fossil DNA recovery from various organisms (bacteria, plants, insects and mammals, including humans) dating back in time from thousands to several million years BP. However, many of these ...

    • DNA Methylation Age Acceleration Is Not Associated with Age of Onset in Parkinson's Disease 

      Gaare, Johannes Jernqvist; Brügger, Kim; Sanchez Nido, Gonzalo; Tzoulis, Charalampos (Journal article; Peer reviewed, 2023)
      Background Epigenetic clocks using DNA methylation (DNAm) to estimate biological age have become popular tools in the study of neurodegenerative diseases. Notably, several recent reports have shown a strikingly similar ...

    • DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival 

      Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2022)
      Background: Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ...

    • DNA methylation in newborns conceived by assisted reproductive technology 

      Håberg, Siri Eldevik; Page, Christian Magnus; Lee, Yunsung; Nustad, Haakon Egdetveit; Magnus, Maria Christine; Haftorn, Kristine Løkås; Carlsen, Ellen Øen; Denault, William Robert Paul; Bohlin, Jon; Jugessur, Astanand; Magnus, Per Minor; Gjessing, Håkon Kristian; Lyle, Robert (Journal article; Peer reviewed, 2022)
      Assisted reproductive technology (ART) may affect fetal development through epigenetic mechanisms as the timing of ART procedures coincides with the extensive epigenetic remodeling occurring between fertilization and embryo ...

    • The DNA methylome of cervical cells can predict the presence of ovarian cancer 

      Barrett, James E.; Jones, Allison; Evans, Iona; Reisel, Daniel; Herzog, Chiara; Chindera, Kantaraja; Kristiansen, Mark; Leavy, Olivia C.; Manchanda, Ranjit; Bjørge, Line; Zikan, Michal; Cibula, David; Widschwendter, Martin (Journal article; Peer reviewed, 2022)
      The vast majority of epithelial ovarian cancer arises from tissues that are embryologically derived from the Müllerian Duct. Here, we demonstrate that a DNA methylation signature in easy-to-access Müllerian Duct-derived ...

    • DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion 

      Silva-Pinheiro, Pedro; Pardo-Hernández, Carlos; Reyes, Aurelio; Tilokani, Lisa; Mishra, Anup; Cerutti, Raffaele; Li, Shuaifeng; Rozsivalova, Dieu-Hien; Valenzuela, Sebastian; Dogan, Sukru A.; Peter, Bradley; Fernández-Silva, Patricio; Trifunovic, Aleksandra; Prudent, Julien; Minczuk, Michal; Bindoff, Laurence Albert; Macao, Bertil; Zeviani, Massimo; Falkenberg, Maria; Viscomi, Carlo (Journal article; Peer reviewed, 2021)
      Mutations in POLG, encoding POLγA, the catalytic subunit of the mitochondrial DNA polymerase, cause a spectrum of disorders characterized by mtDNA instability. However, the molecular pathogenesis of POLG-related diseases ...

    • DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients 

      Olsen, Maria Belland; Huse, Camilla; Sousa, Mirta; Murphy, Sarah Louise Mikalsen; Sarno, Antonio; Obermann, Tobias Sebastian; Yang, Kuan; Holter, Jan Cato; Jørgensen, Marthe Jøntvedt; Christensen, Erik Egeland; Wang, Wei; Ji, Ping; Heggelund, Lars; Hoel, Hedda; Dyrhol-Riise, Anne Ma; Gregersen, Ida; Aukrust, Pål; Bjørås, Magnar; Halvorsen, Bente; Dahl, Tuva Børresdatter (Journal article; Peer reviewed, 2022)
      Purpose: Reactive oxygen species (ROS) are an important part of the inflammatory response during infection but can also promote DNA damage. Due to the sustained inflammation in severe Covid-19, we hypothesized that ...

    • Do Conspiracy Theories Shape or Rationalize Vaccination Hesitancy Over Time? 

      van Prooijen, Jan-Willem; Böhm, Nienke (Journal article; Peer reviewed, 2023)
      Conspiracy beliefs are associated with vaccination hesitancy, which is commonly interpreted as evidence that conspiracy theories contribute to a worldview that damages public health. An alternative, and often ignored, ...

    • Do differences in diagnostic criteria for late fetal growth restriction matter? 

      Mylrea-Foley, Bronacha; Napolitano, Raffaele; Gordijn, Sanne; Wolf, Hans; Lees, Christoph C.; Stampalija, Tamara; Arabin, B.; Berger, A.; Bergman, E.; Bhide, A; Bilardo, C.M.; Breeze, A.C.; Brodszki, J.; Calda, P.; Cesari, E.; Cetin, I.; Derks, J.; Ebbing, Cathrine; Ferrazzi, E.; Frusca, T.; Ganzevoort, W.; Gyselaers, W.; Hecher, K.; Klaritsch, P.; Krofta, L.; Lindgren, P.; Lobmaier, S.M.; Marlow, N.; Maruotti, G.M.; Mecacci, F.; Myklestad, Kirsti; Prefumo, F.; Raio, L.; Richter, J.; Sande, Ragnar; Valensise, H.; Visser, G.H.A.; Wee, L. (Journal article; Peer reviewed, 2023)
      BACKGROUND Criteria for diagnosis of fetal growth restriction differ widely according to national and international guidelines, and further heterogeneity arises from the use of different biometric and Doppler reference ...

    • Do direct oral anticoagulants (DOACs) cause delayed surgery, longer length of hospital stay, and poorer outcome for hip fracture patients? 

      Leer-Salvesen, Sunniva; Dybvik, Eva Hansen; Ranhoff, Anette Hylen; Husebø, Bjørn Liljestrand; Dahl, Ola Einar; Engesæter, Lars B.; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2020)
      Purpose The perioperative consequences of direct oral anticoagulants (DOACs) in hip fracture patients are not sufficiently investigated. The primary aim of this study was to determine whether DOAC-users have delayed surgery ...

    • Do Disease Stories Need a Hero? Effects of Human Protagonists on a Narrative Visualization about Cerebral Small Vessel Disease 

      Mittenentzwei, S.; Weiß, V.; Schreiber, S.; Garrison, Laura Ann; Bruckner, Stefan; Pfister, M.; Preim, B.; Meuschke, M. (Journal article; Peer reviewed, 2023)
      Authors use various media formats to convey disease information to a broad audience, from articles and videos to interviews or documentaries. These media often include human characters, such as patients or treating physicians, ...

    • Do ectomycorrhizal exploration types reflect mycelial foraging strategies? 

      Jörgensen, Karolina Maria; Clemmensen, Karina E.; Wallander, Håkan; Lindahl, Björn D. (Journal article; Peer reviewed, 2022)
      Ectomycorrhizal exploration types are commonly assumed to denote spatial foraging patterns and resource-related niches of extraradical mycelia. However, empirical evidence of the consistency of foraging strategies within ...

    • Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood? 

      Jami, Eshim S.; Hammerschlag, Anke R.; Sallis, Hannah M.; Qiao, Zhen; Andreassen, Ole A.; Magnus, Per Minor; Njølstad, Pål Rasmus; Havdahl, Alexandra; Pingault, Jean-Baptiste; Evans, David M.; Munafò, Marcus R.; Ystrom, Eivind; Bartels, Meike; Middeldorp, Christel (Journal article; Peer reviewed, 2023)
      Parental genes may indirectly influence offspring psychiatric outcomes through the environment that parents create for their children. These indirect genetic effects, also known as genetic nurture, could explain individual ...

    • Do EU goals matter? Assessing the localization of sustainable urban logistics governance goals in Norwegian cities 

      Shrestha, Subina; Haarstad, Håvard (Journal article; Peer reviewed, 2023)
      Sustainable urban logistics is imperative to meet urban sustainability goals. In the European context, the European Union (EU) set an ambitious target in 2011 of essentially CO2-free urban logistics by 2030. However, it ...

    • Do Genetic Variants Modify the Effect of Smoking on Risk of Preeclampsia in Pregnancy? 

      Bauer, Anna E.; Avery, Christy L.; Shi, Min; Weinberg, Clarice R.; Olshan, Andrew F.; Harmon, Quaker E.; Luo, Jingchun; Yang, Jenny; Manuck, Tracy; Wu, Michael C.; Klungsøyr, Kari; Trogstad, Lill; Magnus, Per Minor; Engel, Stephanie M. (Journal article; Peer reviewed, 2021)
      Objective: Maternal smoking is associated with as much as a 50% reduced risk of preeclampsia, despite increasing risk of other poor pregnancy outcomes that often co-occur with preeclampsia, such as preterm birth and fetal ...

    • Do Ideals Differ and Matter? An Investigation of Authentic Leadership Ideals Among Norwegian Military Officers Across Generations – and Its Impact on Leadership Practice 

      Olsen, Olav Kjellevold; Johansen, Rino Bandlitz; Hystad, Sigurd William (Journal article; Peer reviewed, 2021)
      The aim of the present study was to learn more about the content of leadership ideals among Norwegian military officers, and to what degree such ideals influence the officers’ actual leadership practice. We have also ...

    • Do informal Networks Increase Migrants’ Over-Education? Comparing Over-Education for Natives, Migrants and Second Generations in Italy and Assessing the Role of Networks in Generating It 

      VanWolleghem, Pierre-Georges; De Angelis, Marina; Scicchitano, Sergio (Journal article; Peer reviewed, 2022)
      Whilst migration has become a structural feature of most European countries, the integration of foreigners in the labour market continues to raise concerns. Evidence across countries shows that migrants are more often ...

    • Do Parental Education-Related Inequality Matter in Child and Adolescent Utilization of Mental Health Services: Results From a Norwegian Register Linkage Study 

      Bøe, Tormod; Hysing, Mari; Askeland, Kristin Gärtner; Skogen, Jens Christoffer; Heradstveit, Ove (Journal article; Peer reviewed, 2021)
      Equitable access to health care point to equal access to care for those with equal needs, but pro-rich and pro-educated inequities have been documented in specialized mental health care utilization. This study aimed to ...

    • Do parental stimulation practices modify the effect of child’s health status on early developmental risk? Findings from a hospitalized cohort 

      Rasheed, Muneera Abdul; Mughis, Waliyah; Niaz, Maira; Hasan, Babar S. (Journal article; Peer reviewed, 2021)
      The current study conducted in Pakistan aimed to test if parental stimulation practices modify the effect of general child health status on early developmental risks in hospitalized children. Development was assessed using ...

    • Do people demand fact-checked news? Evidence from U.S. Democrats 

      Chopra, Felix; Haaland, Ingar Kyrkjebø; Roth, Christopher (Journal article; Peer reviewed, 2022)
      In a large-scale online experiment with U.S. Democrats, we examine how the demand for a newsletter about an economic relief plan changes when the newsletter content is fact-checked. We first document an overall muted demand ...