Blar i University of Bergen Library på tittel
Viser treff 5688-5707 av 9893
-
Metabolic factors and the risk of small intestine cancers: Pooled study of 800 000 individuals in the metabolic syndrome and cancer project
(Journal article; Peer reviewed, 2021)To explore the largely unknown etiology of small intestine cancer, we examinedmetabolic factors and risk of small intestine cancer overall and by subtypes. Among404 220 women and 403 265 men in six European cohorts, we ... -
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines
(Journal article; Peer reviewed, 2022)Background Most in vitro cancer cell experiments have been performed using 2D models. However, 3D spheroid cultures are increasingly favored for being more representative of in vivo tumor conditions. To overcome the ... -
Metabolic predictors of pain, fatigue, depression and quality of life in people with long-term type 1 diabetes—the Dialong study
(Journal article; Peer reviewed, 2022)Aim To examine associations of metabolic parameters (mean 30 years' time-weighted HbA1c and low-density lipoprotein-cholesterol [LDL-c], current methionine sulfoxide [MetSO], advanced glycation end products [AGEs], ... -
Metabolic rates, feed intake, appetite control, and gut transit of clownfish Amphiprion ocellaris exposed to increased temperature and limited feed availability
(Journal article; Peer reviewed, 2022)Episodes of elevated temperature, combined with lower feed availability, are among the predicted scenarios of climate change representing a challenge for coral reef fish. We investigated the response of clownfish (Amphiprion ... -
Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease
(Journal article; Peer reviewed, 2023)Background: The valine (branched-chain amino acid) metabolite 3-hydroxyisobutyrate (3-HIB), produced by 3-Hydroxyisobutyryl-CoA Hydrolase (HIBCH), is associated with insulin resistance and type 2 diabetes, but implicated ... -
Metabolically (un)healthy obesity and risk of obesity-related cancers: a pooled study
(Journal article; Peer reviewed, 2023)Background Studies of obesity with or without metabolic aberrations, commonly termed metabolically unhealthy or healthy obesity, in relation to cancer risk are scarce. Methods We investigated body mass index (normal ... -
Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice
(Journal article; Peer reviewed, 2023)Background Although imatinib is a well-established first-line drug for treating a vast majority of gastrointestinal stromal tumours (GIST), GISTs acquire secondary resistance during therapy. Multi-omics approaches provide ... -
Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity
(Journal article; Peer reviewed, 2019)Clinical end-stage parameters define the pregnancy disorders preeclampsia and fetal growth restriction while classification of the underlying placental dysfunction is missing and urgently needed. Flt-1 (FMS-like tyrosine ... -
Metagenome-assembled genome distribution and key functionality highlight importance of aerobic metabolism in Svalbard permafrost
(Journal article; Peer reviewed, 2020)Permafrost underlies a large portion of the land in the Northern Hemisphere. It is proposed to be an extreme habitat and home for cold-adaptive microbial communities. Upon thaw permafrost is predicted to exacerbate increasing ... -
Metagenomic tools in microbial ecology research
(Journal article; Peer reviewed, 2021)Ability to directly sequence DNA from the environment permanently changed microbial ecology. Here, we review the new insights to microbial life gleaned from the applications of metagenomics, as well as the extensive set ... -
Metainferential Reasoning on Strong Kleene Models
(Journal article; Peer reviewed, 2021)Barrio et al. (Journal of Philosophical Logic, 49(1), 93–120, 2020) and Pailos (Review of Symbolic Logic, 2020(2), 249–268, 2020) develop an approach to define various metainferential hierarchies on strong Kleene models ... -
Metal-Detecting Rallies: Characterizing the Phenomenon, Understanding the Challenges, and Identifying Strategies for Heritage Protection
(Journal article; Peer reviewed, 2022)Hobby metal detectorists search for archaeological finds as individuals and within groups, the latter being the focus of this article. Such groups come together as “clubs” and “meetings,” but also as part of large, often ... -
Metallionenivåer i blod fra pasienter med metall-mot-metall-hofteprotese
(Journal article; Peer reviewed, 2021)Bakgrunn: BHR-protese (Birmingham hip resurfacing) er satt inn i hoften til 445 personer i Norge. Bivirkninger av metallfrigjøring fra metall-mot-metall-leddflater av kobolt-krom-legering kan forekomme. Målet med studien ... -
Metastatic tumor of the interventricular septum mimicking myocardial calcification: The role of multimodality imaging
(Journal article; Peer reviewed, 2021)Recently, there has been focus on how a round-shaped metastatic or dystrophic myocardial calcification, a rare type of myocardial pathology with different imaging appearances, can mimic a tumor in the basal interventricular ... -
Meta‑Analyses of the Associations Between Disinhibited Social Engagement Behaviors and Child Attachment Insecurity or Disorganization
(Journal article, 2021)Children with disinhibited social engagement disorder show reduced reticence with strangers, do not check back with their caregiver after venturing away, and may willingly leave with an unfamiliar adult. The recent DSM-5 ... -
Meteorological conditions and cloud effects on surface radiation balance near Helheim glacier and Jakobshavn isbræ (Greenland)using ground-based observations.
(Journal article; Peer reviewed, 2021)The surface radiation budget is an essential component of the total energy exchange between the atmosphere and the Earth’s surface. Measurements of radiative fluxes near/on ice surfaces are sparse in the polar regions, ... -
Meteorological observations in tall masts for the mapping of atmospheric flow in Norwegian fjords
(Journal article; Peer reviewed, 2020)Since 2014, 11 tall meteorological masts have been erected in coastal areas of mid-Norway in order to provide observational data for a detailed description of the wind conditions at several potential fjord crossing sites. ... -
Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study
(Journal article; Peer reviewed, 2022-01-28)Background: Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Journal article; Peer reviewed, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
(Journal article; Peer reviewed, 2021)Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a ...