• CT-defined emphysema in COPD patients and risk for change in desaturation status in 6-min walk test 

      Wåtevik, Marie; Frisk, Bente; Real, Francisco Gomez; Hardie, Jon Andrew; Bakke, Per; Eagan, Tomas Mikal Lind; Johannessen, Ane (Journal article; Peer reviewed, 2021)
      Background Emphysema and exercise induced desaturation (EID) are both related to poorer COPD prognosis. More knowledge of associations between emphysema and desaturation is needed for more efficient disease management. ...
    • The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease 

      Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune; Tangedal, Solveig; Haaland, Ingvild; Hiemstra, Pieter S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022)
      Background The lower airways microbiome and host immune response in chronic pulmonary diseases are incompletely understood. We aimed to investigate possible microbiome characteristics and key antimicrobial peptides and ...
    • The pulmonary mycobiome—A study of subjects with and without chronic obstructive pulmonary disease 

      Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Leiten, Elise Orvedal; Haaland, Ingvild; Husebø, Gunnar Reksten; Knudsen, Kristel Svalland; Drengenes, Christine; Sanseverino, Walter; Paytuví-Gallart, Andreu; Nielsen, Rune (Journal article; Peer reviewed, 2021-04-07)
      Background: The fungal part of the pulmonary microbiome (mycobiome) is understudied. We report the composition of the oral and pulmonary mycobiome in participants with COPD compared to controls in a large-scale single-centre ...
    • Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable? 

      Nielsen, Rune; Xue, Yaxin; Jonassen, Inge; Haaland, Ingvild; Kommedal, Øyvind; Wiker, Harald Gotten; Drengenes, Christine; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2021)
      Objective Little is known concerning the stability of the lower airway microbiome. We have compared the microbiota identified by repeated bronchoscopy in healthy subjects and patients with ostructive lung diseaseases ...