• Bioactive Metabolites of Marine Origin Have Unusual Effects on Model Membrane Systems 

      Jakubec, Martin; Totland, Christian; Rise, Frode; Chamgordani, Elahe Jafari; Paulsen, Britt; Maes, Louis; Matheeussen, An; Gundersen, Lise-Lotte; Halskau, Øyvind (Journal article; Peer reviewed, 2020)
      Marine sponges and soft corals have yielded novel compounds with antineoplastic and antimicrobial activities. Their mechanisms of action are poorly understood, and in most cases, little relevant experimental evidence is ...
    • Recombinant Analogs of Sea Anemone Kunitz-Type Peptides Influence P2X7 Receptor Activity in Neuro-2a Cells 

      Pislyagin, Evgeny A.; Menchinskaya, Ekaterina S.; Gladkikh, Irina N.; Kvetkina, Aleksandra N.; Sintsova, Oksana Vladimirovna; Popkova, Darya V.; Kozlovskiy, Sergei A.; Gorpenchenko, Tatiana Y.; Likhatskaya, Galina N.; Kaluzhskiy, Leonid A.; Ivanov, Alexis S.; Andreev, Yaroslav A.; Kozlov, Sergey A.; Dmitrenok, Pavel S.; Aminin, Dmitry L.; Leychenko, Elena V. (Journal article; Peer reviewed, 2023)
      Purinergic P2X7 receptors (P2X7) have now been proven to play an important role and represent an important therapeutic target in many pathological conditions including neurodegeneration. Here, we investigated the impact ...
    • Salmon Protein Hydrolysate Potentiates the Growth Inhibitory Effect of Bicalutamide on Human Prostate Cancer Cell Lines LNCaP and PC3 by Modulating Iron Homeostasis 

      Bjerknes, Christian; Framroze, Bomi; Currie, Crawford; Pettersen, Caroline Hild; Axcrona, Karol; Hermansen, Erland (Journal article; Peer reviewed, 2022)
      Prostate cancer is a common cause of cancer death in men. In advanced stages of prostate cancer, androgen deprivation therapy (ADT) is initiated. Despite ADT, prostate cancers invariably progress to become androgen ...