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dc.contributor.authorNilsen, Roy Miodinien_US
dc.contributor.authorLeoncini, Emanueleen_US
dc.contributor.authorGastaldi, Paoloen_US
dc.contributor.authorAllegri, Valentinaen_US
dc.contributor.authorAgostino, Roccoen_US
dc.contributor.authorFaravelli, Francescaen_US
dc.contributor.authorFerrazzoli, Federicaen_US
dc.contributor.authorFinale, Enricoen_US
dc.contributor.authorGhirri, Paoloen_US
dc.contributor.authorScarano, Gioacchinoen_US
dc.contributor.authorMastroiacovo, Pierpaoloen_US
dc.PublishedItalian Journal of Pediatrics 2016, 42(1):65eng
dc.description.abstractBackground: Women in many countries are advised to use folic acid supplements before and early during pregnancy to reduce the risk of neural tube defects in their infants. This study aimed to update the prevalence and to identify possible determinants of preconception folic acid supplement use in Italian women. Methods: The study was based on cross-sectional data from seven maternity clinics located in six Italian regions from January to June, 2012. Data on maternal characteristics and supplement use were collected for 2,189 women using a self-administered questionnaire. Results: Preconception folic acid use was reported by 23.5 % (n = 515) of the participants. Of these, 479 (93 %) women had taken folic acid supplements on a daily basis as recommended by the health authorities. Women who both had intended their pregnancy and had requested a preconception health visit to a doctor/gynecologist were substantially more likely than the reference group to initiate folic acid supplementation before their pregnancy (48.6 versus 4.8 %). Preconception folic acid use was also associated with higher maternal age, higher education, marriage/cohabitation, lower parity, infertility treatments, and chronic disease. Conclusions: Data from seven maternity clinics located in six Italian regions indicate that preconception folic acid supplement use in many Italian women is low. Women who do not plan their pregnancy or do not request a preconception health visit to their doctor have among the lowest prevalence of preconception folic acid use. Improving folate status in these and other supplemental non-users may have important disease preventive effects.en_US
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.subjectFolic acideng
dc.subjectNeural tube defectseng
dc.titlePrevalence and determinants of preconception folic acid use: an Italian multicenter surveyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2016 The Authors

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