Visual Analysis of Protein-Protein Interaction

Abstract

Over the last decade there has been a steady increase in the focus of research into Protein-Protein docking. The Docking software provides a plausible configuration to a Protein-Protein Interaction. The docking will also provide analysis and ranking of said plausible configuration of Protein-Protein Interaction. The Docking softwares are getting more reliable, but there are still parameters that the software can’t handle, and domain experts have to manually explore the configurations to find and select the relevant ones, which is a time consuming process. With our software, the time used by domain experts to explore the configurations, will be reduced. This software provides a nice overview of the connections between the two proteins in a Protein-Protein Interaction, and provides 3D visual aid to locate the spatial orientation of the contact zone in the proteins, and the Amino Acid pairs in the contact zones spatial orientation to each other.