Browsing Master theses by Subject "CEL-MODY"
Now showing items 1-2 of 2
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Interplay of the proteotoxic CEL-MODY protein and oncogenic KRAS in pancreatic cancer development
(Master thesis, 2024-06-03)Challenges in diagnosing and treating pancreatic cancer make it the fourth-leading cause of cancer-related deaths. Survival rates remain dismally low, and the molecular mechanisms driving this malignancy are still inadequately ... -
The CEL VNTR in pancreatic disease: Effects of cysteine residues in pathogenic carboxyl ester lipase variants
(Master thesis, 2023-06-01)Carboxyl ester lipase (CEL) is a digestive enzyme mainly expressed in the acinar cells of the pancreas. CEL hydrolyses dietary fat, cholesteryl esters and fat-soluble vitamins. The protein is structurally divided into two ...