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Browsing Master theses by Subject "XLF and PAXX"

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    • Making in vivo models viable again: Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53 

      Castaneda Zegarra, Sergio Miguel (Master thesis, 2019-06-28)
      Non-Homologous End-Joining (NHEJ) is the major DNA repair pathway that senses, processes and ligates DNA double strand breaks (DSBs) in higher eukaryotes, functionally throughout the cell cycle. The NHEJ involves four core ...

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