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dc.contributor.authorEgeland, Grace M.en_US
dc.contributor.authorAkerkar, Rupali Rajendraen_US
dc.contributor.authorKvåle, Runeen_US
dc.contributor.authorSulo, Gerharden_US
dc.contributor.authorTell, Grethe S.en_US
dc.contributor.authorBakken, Inger Johanne Landsjøåsenen_US
dc.contributor.authorEbbing, Martaen_US
dc.PublishedEgeland GM, Akerkar RR, Kvåle R, Sulo G, Tell GST, Bakken IJ, Ebbing M. Hospitalised patients with unexplained chest pain: incidence and prognosis. Journal of Internal Medicine. 2019;286:(5)562-572.eng
dc.description.abstractBackground: The prognosis of unexplained chest pain patients provides valuable information for evaluation of health services. Objective: To examine prognosis of unexplained chest pain. Methods: Using data from in‐ and outpatient hospital visits in Norway of patients discharged with a main diagnosis of unexplained chest pain (ICD‐10: R072–R074) in 2010–2012, the 1‐year incidence of coronary heart disease (CHD), any cardio‐vascular disease (CVD) and mortality was evaluated. Cases with prior 2‐year history of CVD or chest pain were excluded. Cox proportional hazards evaluated outcomes by patient characteristics and standardized mortality ratios evaluated observed versus expected mortality. Results: Of 59 569 patients identified (20–89 years of age), the majority (86%) were referred to hospital by out‐of‐hours emergency care centres. Subsequent CHD was noted for 12.5%, 19.5% and 25.0% of men and 7.2%, 11.0%, 14.0% of women aged 45–64, 65–74 and 75–89 years, respectively. The per cent of deaths attributed to CVD were greatest within the first 2 months of postdischarge. Total mortality rates (per 1000 person‐years) were 6.6 in men and 4.7 in women aged 45–64 and 69.2 in men and 39.5 in women aged 75–89 years. Relative to the general population, mortality was 53% and 45% higher for men and women under 65 years of age, respectively, attributed primarily to non‐CVD causes. Conclusion: Patients in Norway discharged with unexplained chest pain are an at‐risk group in terms of incident CHD, any CVD and mortality, including non‐CVD mortality during the first‐year postdischarge. The results suggest that unexplained chest pain patients may benefit from greater healthcare coordination between medical disciplines.en_US
dc.rightsAttribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0eng
dc.subjectCardiovascular diseaseeng
dc.subjectChest paineng
dc.subjectSocioeconomic statuseng
dc.titleHospitalised patients with unexplained chest pain: incidence and prognosisen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2019 The Author(s)
dc.source.journalJournal of Internal Medicine

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Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0
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