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dc.contributor.authorWilhelmsen-Langeland, Aneen_US
dc.contributor.authorSaxvig, Ingvild W.en_US
dc.contributor.authorJohnsen, Emma Holeen_US
dc.contributor.authorMarszalek, Maja Annaen_US
dc.contributor.authorAndersen, Maria Isolde Wiigen_US
dc.contributor.authorSætre, Vild Katrineen_US
dc.contributor.authorLundervold, Astrien_US
dc.contributor.authorVedaa, Øysteinen_US
dc.contributor.authorNordhus, Inger Hildeen_US
dc.contributor.authorPallesen, Ståleen_US
dc.contributor.authorBjorvatn, Bjørnen_US
dc.PublishedWilhelmsen-Langeland AB, Saxvig IW, Johnsen, Marszalek, Andersen, Sætre, Lundervold A, Vedaa Ø, Nordhus IH, Pallesen S, Bjorvatn B. Patients with delayed sleep-wake phase disorder show poorer executive functions compared to good sleepers. Sleep Medicine. 2019;54:244-249eng
dc.description.abstractObjective: Delayed Sleep-Wake Phase Disorder (DSWPD) is associated with negative outcomes, including reduced daytime performance and difficulties with treatment adherence. These outcomes are mediated by executive functions (EF). In this study, we investigated whether patients with DSWPD report inferior EF compared to a control group. The study consisted of 40 patients diagnosed with DSWPD (12 males, mean age 20.7 (±3.1)) and 20 healthy controls (six males, 21.3 (±2.2), p = 1.00) between 16 and 25 years (p = 0.42). Methods: Behavior Rating Inventory of Executive Function-Adult version Self-Report (BRIEF-A) was used for adults ≥18 years (DSWPD n = 28; controls n = 17) whereas Behavior Rating Inventory of Executive Function Self-Report Version (BRIEF-SR) was used for assessment of EF in adolescents <18 years (DSWPD n = 12; controls n = 3). Independent samples t-tests were used to compare patients to controls. Results: The total group of patients with DSWPD scored significantly poorer compared to the control group on the main indexes; Behavioral Regulation Index (BRI) (p = <0.0005), Metacognition Index (MI) (p = <0.0005), and Global Executive Composite (GEC) (p = <0.0005). The adult group with DSWPD scored significantly poorer than the adult control group on eleven of the twelve BRIEF-A scales. Among patients <18 years, the DSWPD-group scored significantly poorer than the control group on 8 of the 13 BRIEF-SR-scales. Conclusion: Patients with DSWPD reported significantly poorer EF compared to controls. Assessment of EF in patients with DSWPD can be valuable for understanding the consequences of the disorder regarding treatment tailoring and adherence.en_US
dc.rightsAttribution CC BY-NC-NDeng
dc.titlePatients with delayed sleep-wake phase disorder show poorer executive functions compared to good sleepersen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2019 Elsevier
dc.source.journalSleep Medicine

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