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dc.contributor.authorPetersen, Tanja Gramen_US
dc.contributor.authorForthun, Ingeborgen_US
dc.contributor.authorLange, Theisen_US
dc.contributor.authorVilladsen, Sarah Fredsteden_US
dc.contributor.authorNybo Andersen, Anne-Marieen_US
dc.contributor.authorUldall, Peteren_US
dc.contributor.authorStrandberg-Larsen, Katrineen_US
dc.PublishedPetersen TG, Forthun I, Lange T, Villadsen, Nybo Andersen A, Uldall P, Strandberg-Larsen K. Cerebral palsy among children of immigrants in Denmark and the role of socioeconomic status. European journal of paediatric neurology. 2019;23(3):507-516eng
dc.description.abstractBackground Children of immigrants in Denmark have excess risk for some of the most well-established risk factors for cerebral palsy (CP). Objectives To study differences in risk of CP between children of immigrants and children of Danish-born mothers, and explore whether socioeconomic status drives any potential association. Methods A register-based cohort study including 1,274,616 children born in Denmark between 1981 and 2007. Of these, 2807 had a validated CP diagnosis in the Danish CP Register. We estimated the risk of CP as odds ratios (OR) using logistic regression and assessed mediation through socioeconomic status using natural effect models. Results In children of Danish-born mothers, 2.2/1000 had CP overall and the prevalence was similar for children of immigrants. However, children of immigrants had lower risk of unilateral spastic CP than children of Danish native-born mothers; OR = 0.59 (95% CI:0.38–0.91) for Western and OR = 0.79 (95% CI:0.61–1.03) for Non-Western immigrants. By contrast, the risk of bilateral spastic CP was higher in children of Non-Western immigrants (OR = 1.27 (95% CI:1.05–1.53)), especially from Turkey and Pakistan compared with children of Danish native-born mothers. The mediation analysis revealed an indirect effect (through maternal educational level and household income) with an OR of 1.06 (95% CI:0.99–1.14) for children of Non-Western immigrants. Conclusions While children of immigrants had lower risk of unilateral spastic CP than children of Danish-born mothers, the risk of bilateral spastic CP was increased in children of Non-Western immigrants. Socioeconomic status did not appear to be a significant contributor to the increased risk of bilateral spastic CP.en_US
dc.rightsAttribution CC BY-NC-NDeng
dc.subjectCerebral palsyeng
dc.subjectRisk factorseng
dc.subjectEthnic disparitieseng
dc.titleCerebral palsy among children of immigrants in Denmark and the role of socioeconomic statusen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2019 The Authors
dc.source.journalEuropean journal of paediatric neurology

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