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dc.contributor.authorBerge, Line Idenen_US
dc.contributor.authorRiise, Tronden_US
dc.contributor.authorHundal, Øivinden_US
dc.contributor.authorØdegaard, Ketil Joachimen_US
dc.contributor.authorDilsaver, Stevenen_US
dc.contributor.authorLund, Andersen_US
dc.description.abstractBackground: Persons with diabetes and depression have increased risk of complications and increased mortality. We aimed to investigate the prevalence, clinical characteristics and impact with regard to glycosylated haemoglobin (HbA1c) of depressive disorders in persons with type 1 diabetes at an outpatient specialist diabetes clinic. Findings: A total of 51 persons with type 1 diabetes were diagnosed according to Mini International Neuropsychiatric Interview (M.I.N.I) with regard to dysthymia and previous or ongoing depressive episodes during spring 2005. HbA1c was measured at the day of the interview, and self-reported information on family history of depressive disorders was obtained. Eight persons (16%; 95% CI: 7%, 29%) were in the midst of a major depressive episode, 4 of these also reported a previous episode of depression. Seven of the 8 persons with an ongoing major depressive episode met the criteria for melancholia. Three persons (6%) met the criteria for dysthymia, and 6 persons (12%) had previous episode(s) of depression, without being currently depressed. The 17 (33%; 95% CI: 21%, 48%) persons with ongoing and/or previous depressive disorder had increased HbA1c (8.5%; 95% CI: 7.6%, 9.4%) compared to those without depressive disorders (7.9%; 95% CI: 7.5%, 8.3%), although the difference did not reach statistical significance. Conclusions: Persons with type 1 diabetes had a high prevalence of depressive disorders, mainly depressive episodes that also met the criteria for melancholia, a subtype often considered a more serious and “biologic” form of depression. We were not able to demonstrate that persons with depressive disorders had poorer regulated diabetes compared to those without depressive disorders.en_US
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.subjectDiabetes type 1eng
dc.subjectMelancholic depressioneng
dc.titlePrevalence and characteristics of depressive disorders in type 1 diabetesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2013 Berge et al.; licensee BioMed Central Ltd.
dc.rights.holderLine Iden Berge et al.; licensee BioMed Central Ltd.
dc.source.journalBMC Research Notes

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