Blar i Department of Biological Sciences på tittel
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Notochord development in Atlantic salmon (Salmo salar L.): exploring molecular pathways and putative mechanism of segmentation
(Doctoral thesis, 2014-03-07)Background: A key feature of the vertebrate body plan is the repeated compartments made up of individual vertebra, blood vessels, peripheral nerves and muscle. The vertebral column comprises a series of bony vertebral ... -
The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development
(Peer reviewed; Journal article, 2017-11)We present the development of the notochord of the Atlantic salmon (Salmo salar L.), from early embryo to sexually mature fish. Over the salmon's lifespan, profound morphological changes occur. Cells and gross structures ... -
Novel and Unexpected Microbial Diversity in Acid Mine Drainage in Svalbard (78° N), Revealed by Culture-Independent Approaches
(Peer reviewed; Journal article, 2015-10-13)Svalbard, situated in the high Arctic, is an important past and present coal mining area. Dozens of abandoned waste rock piles can be found in the proximity of Longyearbyen. This environment offers a unique opportunity for ... -
A novel human NatA N-alpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)
(Peer reviewed; Journal article, 2009-05-29)Background: Protein acetylation is among the most common protein modifications. The two major types are post-translational Nε-lysine acetylation catalyzed by KATs (Lysine acetyltransferases, previously named HATs (histone ... -
A novel moderately thermophilic facultative methylotroph within the class Alphaproteobacteria
(Journal article; Peer reviewed, 2021-02-25)Methylotrophic bacteria (non-methanotrophic methanol oxidizers) consuming reduced carbon compounds containing no carbon–carbon bonds as their sole carbon and energy source have been found in a great variety of environments. ... -
A Novel Moderately Thermophilic Type Ib Methanotroph Isolated from an Alkaline Thermal Spring in the Ethiopian Rift Valley
(Journal article; Peer reviewed, 2020-02-13)Aerobic moderately thermophilic and thermophilic methane-oxidizing bacteria make a substantial contribution in the control of global warming through biological reduction of methane emissions and have a unique capability ... -
A novel protist parasite, Salmoxcellia vastator n. gen., n. sp. (Xcelliidae, Perkinsozoa), infecting farmed salmonids in Norway
(Journal article; Peer reviewed, 2021)Background In Norway, x-cell parasites associated with disease in farmed salmonids have been known as a rare phenomenon for two decades. These parasites cause systemic infections in farmed rainbow trout (Oncorhynchus ... -
De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females
(Peer reviewed; Journal article, 2015)Recent studies revealed the power of whole-exome sequencing to identify mutations in sporadic cases with non-syndromic intellectual disability. We now identified de novo missense variants in NAA10 in two unrelated individuals, ... -
Nuclear Phosphatidylinositol 3,4,5-Trisphosphate Interactome Uncovers an Enrichment in Nucleolar Proteins
(Journal article; Peer reviewed, 2021)Polyphosphoinositides (PPIns) play essential roles as lipid signaling molecules, and many of their functions have been elucidated in the cytoplasm. However, PPIns are also intranuclear where they contribute to chromatin ... -
The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth
(Journal article; Peer reviewed, 2022)Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear envelope. Constructed from ~500–1000 nucleoporin proteins each, they are among the largest macromolecular assemblies in eukaryotic cells. ... -
Nuclear receptor targets for environmental pollutants. Modulation of transcriptional activity of pregnane x receptor and peroxisome proliferator-activated receptor gamma in polar bears and zebrafish
(Doctoral thesis, 2016)Liganded nuclear receptors can be viewed as transcriptional dimmers whose activity is adjusted by molecular signals. Since the chemical footprint of humans continue to increase, the numbers of chemicals in the environment ... -
Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with high 47S rRNA levels in cancer cells
(Journal article; Peer reviewed, 2021)The class I phosphoinositide 3-kinase (PI3K) catalytic subunits p110α and p110β are ubiquitously expressed but differently targeted in tumours. In cancer, PIK3CB (encoding p110β) is seldom mutated compared with PIK3CA ... -
Nucleolar roles of the PI3K pathway in cancer and differentiation
(Doctoral thesis, 2017-12-18)The phosphoinositide 3-kinase (PI3K) pathway is essential for many cellular functions including; proliferation, cell survival, differentiation and metabolism. Although this pathway has been well studied in the cytoplasm, ... -
Nutrient and chemical contaminant levels in five marine fish species from Angola—The EAF-Nansen programme
(Journal article; Peer reviewed, 2020)Fish is a rich source of several important nutrients and an important part of the otherwise plant-dominated diet present in Angola. However, fish may also be a source of contaminants. The aim of this study was to analyse ... -
Nutrient Digestibility, Growth, Mucosal Barrier Status, and Activity of Leucocytes From Head Kidney of Atlantic Salmon Fed Marine- or Plant-Derived Protein and Lipid Sources
(Journal article; Peer reviewed, 2021-02-19)Nutrient digestibility, growth, and mucosal barrier status of fish skin, gills, and distal intestine were studied in Atlantic salmon fed feeds based on marine or plant-derived ingredients. The barrier status was assessed ... -
Nutrient fuxes from an Arctic seabird colony to the adjacent coastal marine ecosystem
(Journal article; Peer reviewed, 2022)Seabirds are important vectors for nutrient transfer across ecosystem boundaries. In this seasonal study, we evaluate the impact of an Arctic colony (Alkhornet, Svalbard) of Black-legged Kittiwakes (Rissa tridactyla) and ... -
Nutrient pathways through the microbial food web: principles and predictability discussed, based on five different experiments
(Peer reviewed; Journal article, 2010-11-11)Although explanatory and predictive powers are 2 closely interconnected aspects of conceptual and mathematical models of complex systems, the two are not equivalent. The 2 aspects are discussed here for the microbial part ... -
Nutrient use by tropical ant communities varies among three extensive elevational gradients: A cross-continental comparison
(Journal article; Peer reviewed, 2023)Aim: Many studies demonstrate that climate limits invertebrates along tropical elevational gradients, but we have only a rudimentary understanding of the role of nutrient limitation and climatic seasonality. Here we examined ... -
Nutrigenomic study of lipid metabolism in Atlantic salmon (Salmo salar L.) : the effects of dietary plant oil inclusion
(Doctoral thesis, 2006-09-08)The two dietary trials conducted in the present study (Papers I-III) used dietary rapeseed oil fed in a regression design and a full plant oil blend replacement for fish oil, respectively. The metabolic response of Atlantic ... -
Nutritional and environmental impacts on skin and mucus condition in Atlantic salmon (Salmo salar L.)
(Doctoral thesis, 2015-10-09)The skin and associated mucus layer of Atlantic salmon constitutes its first line of defence against the aqueous environment. Through intensive farming, a range of stressors including both mechanical and environmental ...