Department of Chemistry
Recent Submissions
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Similarity-Based Methods and Machine Learning Approaches for Target Prediction in Early Drug Discovery: Performance and Scope
(Journal article; Peer reviewed, 2020-05)Computational methods for predicting the macromolecular targets of drugs and drug-like compounds have evolved as a key technology in drug discovery. However, the established validation protocols leave several key questions ... -
Variability in the formation and framework polymorphism of metal-organic frameworks based on yttrium(III) and the bifunctional organic linker 2,5-dihydroxyterephthalic acid
(Journal article; Peer reviewed, 2021)Depending on the solvothermal reaction conditions, we obtained three different metal‐organic frameworks with yttrium(III) as metal component and 2,5‐dihdyroxyterepthalic acid (H4dhtp) as bifunctional organic linker: ... -
Extraction of form factors from a four-dimensional angular analysis of ¯B→D∗ℓ−¯νℓ
(Journal article; Peer reviewed, 2019-08-30)An angular analysis of the decay ¯B→D∗ℓ−¯νℓ, ℓ∈{e,μ}, is reported using the full e+e−collision data set collected by the BABAR experiment at the Υ(4S) resonance. One B meson from the Υ(4S)→B¯B decay is fully reconstructed ... -
Total Synthesis of Phorbazole B
(Journal article; Peer reviewed, 2020)Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the ... -
Polymer Injectivity : Experimental Studies of Flow in Porous Media for EOR Polymers
(Doctoral thesis, 2021-02-12)Despite the maturity of the polymer flooding process that is applied in enhanced oil recovery (EOR) technologies, the core of the process, which is the flow of the polymer in porous media, is poorly understood. The types ... -
Associations of physical activity and sedentary time with lipoprotein subclasses in Norwegian schoolchildren: The Active Smarter Kids (ASK) study
(Journal article; Peer reviewed, 2019)Background and aims: Physical activity is favourably associated with certain markers of lipid metabolism. The relationship of physical activity with lipoprotein particle profiles in children is not known. Here we examine ... -
Utvikling av metodikk for screening og bestemmelse av sølvnanopartikler i blåskjell ved bruk av DLS, sp-ICP-MS og EM
(Master thesis, 2020-12-16) -
Lokalisering av (R)-artikain i et lipidbilag
(Master thesis, 2020-12-15)Hensikten med denne oppgaven var å undersøke interaksjonen mellom (R)-artikain og lipidbilag av POPC ved bruk av fast-fase NMR-spektroskopi. Artikain hydroklorid brukes som et lokalbedøvelsesmiddel innen tannbehandling, ... -
Probing myelin-specific membrane proteins using hybrid nanoparticles
(Master thesis, 2020-12-03)Neuroscience is the study of the nervous system and its diseases. Neurological diseases are common and among the least understood class of disease in humans. Demyelinating diseases,, such as multiple sclerosis and ... -
Investigating the Synthesis of Monosubstituted Keggin Polyoxometalates
(Master thesis, 2020-12-03)For any successful catalyst, there needs to be a cheap and reliable route to synthesising the catalytic material. It is therefore desirable to find syntheses that are time efficient, do not require any highly toxic chemicals ... -
Monitoring of the aqueous phase from hydrothermal liquefaction using GC-MS and qNMR
(Master thesis, 2020-11-03)Hydrothermal liquefaction (HTL) is a promising technique used for production of biocrude. Along with the biocrude, there is also produced large amounts of aqueous waste containing high concentrations of both soluble organics ... -
Mechanistic Modelling of Radial Polymer Flow in Porous Media
(Doctoral thesis, 2020-09-29)Polymer flooding is one of the most successful chemically enhanced oil recovery (EOR) methods, and has primarily been implemented to accelerate oil production by sweep improvement. However, research from the last couple ... -
Nitrous Oxide Adsorption and Separation Using CPO-27 Metal-Organic Frameworks
(Master thesis, 2020-08-29)Nitrous oxide N2O is a potent greenhouse gas with a high global warming potential approximately 300 times that of carbon dioxide on a 100-year timescale. In addition, it is the leading ozone-depleting substance emitted in ... -
Smart Surfaces: Design, Structuring and Characterization
(Master thesis, 2016-06-02) -
Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L
(Peer reviewed; Journal article, 2019)For more than four centuries, the intake of Narthecium ossifragum has been associated with poisoning in domesticated animals. Saponins occurring in flowering tops of the plant are considered to cause kidney damage in calves. ... -
Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates
(Peer reviewed; Journal article, 2019)Membrane-binding interfaces of peripheral proteins are restricted to a small part of their exposed surface, so the ability to engage in strong selective interactions with membrane lipids at various depths in the interface, ... -
Kinase chemodiversity from the Arctic: the breitfussins
(Peer reviewed; Journal article, 2019)In this work, we demonstrate that the indole-oxazole-pyrrole framework of the breitfussin family of natural products is a promising scaffold for kinase inhibition. Six new halogenated natural products, breitfussin C–H (3 ... -
«Hvordan skal jeg kunne finne ut av det?» Ein kvalitativ studie av korleis elevar arbeider for å forstå tal og fakta som ikkje gir meining for dei
(Master thesis, 2020-07-17)Dei nye læreplanane skal legge til rette for djupnelæring. Dette medfører mellom anna at utforskande arbeid og kritisk tenking er sentrale satsingsområde i norsk skule. For å kunne fremme elevane sin kompetanse i å lære ...
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