Department of Chemistry
Recent Submissions
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Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection
(Journal article; Peer reviewed, 2024)The EU-OPENSCREEN (EU-OS) European Research Infrastructure Consortium (ERIC) is a multinational, not-for-profit initiative that integrates high-capacity screening platforms and chemistry groups across Europe to facilitate ... -
Exploring FabF as a new target for antibiotic-resistant Pseudomonas aeruginosa: Assay development, fragment screening and hit optimization
(Doctoral thesis, 2024-12-16)Oppdagelsen av antibiotika er utvilsomt blant de største triumfene innen moderne medisin, og har i stor grad forbedret sykdomsforløpet ved de fleste vanlige bakterieinfeksjoner. I dag har triumffanfarene blitt modulert til ... -
Advanced Free Energy Methods in Retrospective and Prospective Drug Design: Application to Serine Proteases
(Doctoral thesis, 2024-12-13)Beregninger av relativ fri bindingsenergi (eng. RBFE) har vokst frem som en foretrukket metode for å veilede kostbare og tidkrevende synteser og andre eksperimenter i legemiddelutvikling på grunn av metodens nærmest ... -
Exposure of Polycyclic Aromatic Hydrocarbons (PAHs) and Crude Oil to Atlantic Haddock (Melanogrammus aeglefinus): A Unique Snapshot of the Mercapturic Acid Pathway
(Journal article; Peer reviewed, 2024)Fish exposed to xenobiotics like petroleum-derived polycyclic aromatic hydrocarbons (PAHs) will immediately initiate detoxification systems through effective biotransformation reactions. Yet, there is a discrepancy between ... -
Advancing Discovery of Polar Polycyclic Aromatic Hydrocarbons via UHPLC-HRMS
(Doctoral thesis, 2024-11-29)Industrielle utslipp fra offshore petroleumsvirksomhet introduserer polysykliske aromatiske hydrokarboner (PAH-er) i marine miljøer. Miljøovervåkning av petroleum-relaterte PAH-er i fisk innebærer måling av et sett av deres ... -
Redesigning Clozapine : Development of Clozapine Analogues for the Potential Treatment of Melanoma Brain Metastases
(Doctoral thesis, 2024-11-22)Kreft er den nest vanligste dødsårsaken i Europa. Mangelen på selektiviteten mellom vev danner bivirkninger, uavhengig om behandlingstype. Utvikling av nye behandlinger kan ta opptil 15 år og er kostbart. Gjenbruk av ... -
Exploring the Potential of Biomass Resources Available in Western Norway
(Doctoral thesis, 2024-10-21)Fornybare energikilder som vind, sol, vannkraft og geotermisk energi kan bidra til å erstatte fossile ressurser for å dekke et energibehov, men de kan ikke erstatte vanlig brukte fossilbaserte kjemiske produkter og ... -
Optimizing Formic Acid-Assisted Co-HTL of Digested Sewage Sludge and Lignocellulosic Waste for Enhanced Bio-Crude Yield and Energy Recovery
(Journal article; Peer reviewed, 2024)In recent years, hydrothermal liquefaction (HTL) has gained attention as a means of enhancing and increasing the production of biofuels from biomass. Co-HTL involves the simultaneous processing of two or more feedstocks, ... -
Extracellular vesicles for breast cancer diagnosis and therapy
(Journal article, 2024)Breast cancer is still suffering from its poor diagnosis and the lack of effective treatment. Despite of recent development of some novel chemicals, which are found to have inspiring therapeutic effects in vitro, their ... -
Thermal stability of polyphenols and carotenoids from Laminaria hyperborea
(Master thesis, 2024-06-03)The green shift, and the focus on an increased blue bioeconomy, has stimulated the growth of sustainable production lines for marine bioactive products for food-, feed-, cosmetics-, and -pharmaceutical industries. Norway ... -
Exploring gas adsorption properties and phase transitions of two M(tppo) metal-organic frameworks
(Master thesis, 2024-06-03)Separation and storage of gases is of interest to the global society in order to minimize emission of greenhouse gases and utilize these gases as resources in their pure form in the chemical industry. This work considers ... -
Videregående elevers opplevelse av mappevurdering i naturfag
(Master thesis, 2024-06-03)Vurdering er en sentral del i utdanningen i den norske skolen. Gjennom den nye læreplanen er det et mål å legge til rette for blant annet dybdelæring og aktiv læring. Dermed blir det viktig at elevene får utføre utforskende ... -
Qualitative and quantitative analyses of unbound phenolic compounds from pollen grains of pine (Pinus uncinata)
(Master thesis, 2024-06-03)The research in this master project is performed within an interdisciplinary RCN (The Research Council of Norway) research project (QUEST-UV: Quantitative estimates of past UV-B irradiance from fossil pollen) and includes ... -
Investigating the Impact of Fermentation on Polyphenolic Content in Cultivated Sugar Kelp (Saccharina latissima): A Comprehensive Study
(Master thesis, 2024-06-03)Seaweeds, classified as macroalgae, are a marine bioresource garnering global attention, primarily due to the increasing demand for new sustainable bioresources. Seaweeds are rich in a variety of bioactive compounds that ... -
Source and fate of ultra-short-chain PFAS in AFFF-impacted water and biota
(Master thesis, 2024-06-24) -
Synthesis and Comparative Analysis of Carbon Dots: A Study on Continuous Flow, Microwave, and Furnace Methods
(Master thesis, 2024-06-03)Karbonprikker (eng.: Carbon Dots) ble først oppdaget i 2004, og siden da har de tiltrukket seg betydelig oppmerksomhet på grunn av deres unike egenskaper, som gjør dem egnet for et bredt spekter av bruksområder. I denne ... -
Kartlegging av LtL-prosessen ved bruk av ulike biomaterialerog geokjemisk analyser.
(Master thesis, 2024-06-03) -
Trace element composition of Norway lobster (Nephrops norvegicus) in the proximity of fish farms
(Master thesis, 2024-06-03)The aquaculture industry in Norway is expected to grow with potential impact on the environment. The common seafood delicacy Norway lobster (Nephrops norvegicus) was studied to see how the vicinity to aquaculture might ... -
Glucuronic Acid in Kombucha: A Multivariate Investigation of White, Green, and Black Tea Kombucha Combining Sensory Profiling, Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy
(Master thesis, 2024-06-03)Kombucha, en fermentert te som er blitt kjent for sine potensielle helsefordeler, har økt i popularitet i takt med den økende interessen for funksjonelle matvarer. Til tross for påstander om oppkvikkende og avgiftende ... -
The Distribution and Elimination of Lufenuron in Atlantic Salmon (Salmo salar)
(Master thesis, 2024-06-03)Salmon lice (Lepeophtheirus salmonis) are a growing problem in the Norwegian aquaculture industry with an estimated annual cost of sea lice management of 525 million USD in 2019 in Norway. Numerous lice treatments exist, ...