Department of Chemistry
Recent Submissions
-
Anthocyanin Profile and Antioxidant Property of Anti-asthma Flowers of Cordyline terminalis (L.) Kunth (Agavaceae)
(Journal article; Peer reviewed, 2020)Cordyline terminalis flower is traditionally used to treat asthma and the purple color of the flower is suggestive of anthocyanins. The purpose of this study was to characterize and determine the antioxidant property of ... -
Acylated Flavone O-Glucuronides from the Aerial Parts of Nepeta curviflora
(Journal article; Peer reviewed, 2020)Nepeta curviflora Boiss. (Syrian catnip) is native to the Middle East. This medicinal plant is commonly used against nervous disorders, rheumatic pains, and high blood pressure. Herbal infusions prepared from various Nepeta ... -
Characterization of a Natural, Stable, Reversible and Colourful Anthocyanidin Network from Sphagnum Moss Based Mainly on the Yellow Trans‐Chalcone and Red Flavylium Cation Forms
(Journal article; Peer reviewed, 2021)Anthocyanins with various functions in nature are one of the most important sources of colours in plants. They are based on anthocyanidins or 3-deoxyanthocyanidins having in common a C15-skeleton and are unique in terms ... -
The multivariate physical activity signature associated with metabolic health in children and youth: An International Children's Accelerometry Database (ICAD) analysis
(Journal article; Peer reviewed, 2020)There is solid evidence for an association between physical activity and metabolic health outcomes in children and youth, but for methodological reasons most studies describe the intensity spectrum using only a few summary ... -
Ethylene-Triggered Formation of Ruthenium Alkylidene from Decomposed Catalyst
(Journal article; Peer reviewed, 2020)Ethylene is known to readily decompose ruthenium-based olefin metathesis catalysts, such as Grubbs second-generation catalyst (GII), by forming the unsubstituted ruthenacyclobutane (Ru-2) that may undergo a 1,2-H shift and ... -
Scope of 3D shape-based approaches in predicting the macromolecular targets of structurally complex small molecules including natural products and macrocyclic ligands
(Journal article; Peer reviewed, 2020)A plethora of similarity-based, network-based, machine learning, docking and hybrid approaches for predicting the macromolecular targets of small molecules are available today and recognized as valuable tools for providing ... -
Volumetric properties of the nucleosides adenosine, cytidine, and uridine in aqueous solution at T = (288.15 and 313.15) K and p = (10 to 100) MPa
(Journal article; Peer reviewed, 2019)Speeds of sound have been measured for aqueous solutions of the nucleosides adenosine, cytidine, and uridine at the temperatures T = (288.15 and 313.15) K and at the pressures p = (10, 20, 40, 60, 80, and 100) MPa. Using ... -
Conformator: A Novel Method for the Generation of Conformer Ensembles
(Journal article; Peer reviewed, 2019)Computer-aided drug design methods such as docking, pharmacophore searching, 3D database searching, and the creation of 3D-QSAR models need conformational ensembles to handle the flexibility of small molecules. Here, we ... -
DENOPTIM: Software for Computational de Novo Design of Organic and Inorganic Molecules
(Journal article; Peer reviewed, 2019)A general-purpose software package, termed DE Novo OPTimization of In/organic Molecules (DENOPTIM), for de novo design and virtual screening of functional molecules is described. Molecules of any element and kind, including ... -
Conjugated ynones in organic synthesis
(Journal article; Peer reviewed, 2019)This review article will consider the preparation and application of ynones in synthetic organic chemistry. Concerning the preparation of these bifunctional compounds, several methodologies starting from propargyl alcohols, ... -
FAME 3: Predicting the sites of metabolism in synthetic compounds and natural products for phase 1 and phase 2 metabolic enzymes
(Journal article; Peer reviewed, 2019)In this work we present the third generation of FAst MEtabolizer (FAME 3), a collection of extra trees classifiers for the prediction of sites of metabolism (SoMs) in small molecules such as drugs, druglike compounds, ... -
Hit Dexter 2.0: Machine-Learning Models for the Prediction of Frequent Hitters
(Journal article; Peer reviewed, 2019)Assay interference caused by small molecules continues to pose a significant challenge for early drug discovery. A number of rule-based and similarity-based approaches have been derived that allow the flagging of potentially ... -
Effect of Larger Pore Size on the Sorption Properties of Isoreticular Metal–Organic Frameworks with High Number of Open Metal Sites
(Journal article; Peer reviewed, 2020)Four isostructural CPO‐54‐M metal‐organic frameworks based on the larger organic linker 1,5‐dihydroxynaphthalene‐2,6‐dicarboxylic acid and divalent cations (M=Mn, Mg, Ni, Co) are shown to be isoreticular to the CPO‐27 ... -
Optimization of Analytical Method for Selenium Speciation in Fish Feed and Feed Ingredients Using a Chemometric Approach
(Master thesis, 2021-03-15)Selenium (Se) is an essential element for humans, as well as for fish, including Atlantic salmon (Salmo salar). One of the main sources of Se and other elements for farmed salmon is the diet. Due to the replacement of ... -
MnDPDP: Contrast agent for imaging and protection of viable tissue
(Journal article; Peer reviewed, 2020-09-10)The semistable chelate manganese (Mn) dipyridoxyl diphosphate (MnDPDP, mangafodipir), previously used as an intravenous (i.v.) contrast agent (Teslascan™, GE Healthcare) for Mn-ion-enhanced MRI (MEMRI), should be reappraised ... -
Emulsion and Surface-Active Properties of Fish Solubles Based on Direct Extraction and after Hydrolysis of Atlantic Cod and Atlantic Salmon Backbones
(Journal article; Peer reviewed, 2021)The focus on natural foods and “clean” labeled products is increasing and encourages development of new biobased ingredients. Fish solubles derived from downstream processing of side stream materials in the fish filleting ... -
Sensory and physicochemical properties of enzymatic protein hydrolysates : Influence of raw material, protease, and downstream processing
(Doctoral thesis, 2021-04-12)The world aquaculture, fisheries and poultry sectors generate large amounts of residual raw materials, such as heads, backbones, and carcasses. Almost 85% of the residual materials from Norwegian aquaculture and fisheries ... -
TAT-Modified Gold Nanoparticles Enhance the Antitumor Activity of PAD4 Inhibitors
(Journal article; Peer reviewed, 2020)Purpose: Histone citrullination by peptidylarginine deiminases 4 (PAD4) regulates the gene expression of tumor suppressor. In our previously study, YW3-56 (356) was developed as a potent PAD4 inhibitor for cancer therapy ... -
Effects of Strain and Kinetics on the H2O2‑Assisted Reconstruction of Ag−Au−Ag Nanorods
(Journal article; Peer reviewed, 2020)Morphology of Ag nanocrystals (NCs) is essential to the NC application in catalysis, optics, and as antibacterial agents. Therefore, it is important to develop synthetic methods and understand the evaluation of NC morphology ... -
Synthesis of penta-fold twinned Pd-Au-Pd segmental nanorods for in situ monitoring catalytic reaction
(Journal article; Peer reviewed, 2020)Multimetallic nanomaterials have many applications. The controlled synthesis of multimetallic nanomaterials is highly desired. We report a study on using penta-fold twinned (PFT) Au nanorods (NRs) as seeds to synthesize ...
RSS 2.0