Department of Chemistry
Recent Submissions
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Selective Hydrodeoxygenation of Lignin-Derived Phenols to Aromatics Catalyzed by Nb2O5-Supported Iridium
(Journal article; Peer reviewed, 2022)The dominating catalytic approach to aromatic hydrocarbons from renewables, deoxygenation of phenol-rich depolymerized lignin bio-oils, is hard to achieve: Hydrodeoxygenation (HDO) of phenols typically leads to loss of ... -
Method development in analysis of cerium dioxide and titanium dioxide nanoparticles with sp-ICP-MS
(Master thesis, 2022-08-01)Denne oppgaven tar for seg analyse av ceriumdioksid og titandioksid ved hjelp av sp-ICP-MS i vann samt. biologiske matriser. En deloppgave er å utvikle en metode for å raffinere størrelsesfordelingen til nanosuspensjoner. -
Development and optimisation of processes for active pharmaceutical ingredients:A modern approach to the synthesis of the potent anti-leukaemia drug -Quinacrine
(Master thesis, 2022-08-15)The extensive testing and approval needed before a new active pharmaceutical can be used in treatments of patients has lead to an increased interest in drug repurposing of older approved drugs as treatments for other ... -
An environmentally benign and high-rate Appel type reaction
(Journal article; Peer reviewed, 2022)A high rate, selective, and productive Appel type reaction was developed. The method allows for ipso-substitution of the alcoholic hydroxy group with halogens ∈ [Cl, Br, I]. The method demands mild reaction conditions that ... -
Advancing quantification methods for polyphenols in brown seaweeds—applying a selective qNMR method compared with the TPC assay
(Journal article; Peer reviewed, 2022)Introduction Brown seaweeds are a sustainable biomass with a potential for various industrial applications. Polyphenols are an important contributor to this potential. Objective The aim was total quantification of ... -
Synthesis, Characterization and Catalytic Applications of N-Heterocyclic Carbene Based Vanadium Complexes.
(Master thesis, 2022-05-31)New tri- and tetradentate O-functionalized NHC oxo- and imido vanadium complexes have been synthesized and characterized. The complexes were preliminary tested for catalytic activity towards coupling of CO2 and epoxides ... -
Investigation of Adsorption Properties in the Metal-Organic Framework CPO-54-Ni
(Master thesis, 2022-06-01) -
Investigation of Gas Adsorption and Separation Properties in the Metal-Organic Framework CPO-54-Co
(Master thesis, 2022-06-01) -
Development, validation and application of in-silico methods to predict the macromolecular targets of small organic compounds
(Doctoral thesis, 2021-12-10)Computational methods to predict the macromolecular targets of small organic drugs and drug-like compounds play a key role in early drug discovery and drug repurposing efforts. These methods are developed by building ... -
Associations of lipoprotein particle profile and objectively measured physical activity and sedentary time in schoolchildren: a prospective cohort study
(Journal article; Peer reviewed, 2022-01-21)Background: Our understanding of the mechanisms through which physical activity might benefit lipoprotein metabolism is inadequate. Here we characterise the continuous associations between physical activity of different ... -
SuspensionFeeding Benthic Species’ Physiological and Microbiome Response to Salmon Farming and Associated Environmental Changes
(Journal article; Peer reviewed, 2022)Caged salmon farming is increasingly undertaken in water bodies with strong hydrodynamics where hard and mixed substrate habitats are more prevalent. Yet, these structurally complex and heterogeneous habitats support diverse ... -
Selective hydrodeoxygenation of phenolic compounds by oxide-supported iridium nanoparticles
(Master thesis, 2022-06-01)As more focus is placed on renewable energy to combat climate change and to meet the increasing energy demand, research into new energy sources has become more relevant than ever. A promising source of renewable energy as ... -
Fast photodegradation of antibiotics and dyes by anionic surfactant-aided CdS/ZnO nanodispersion
(Journal article; Peer reviewed, 2022)The photocatalytic technology has broad applications in energy and environmental science. In this study, we synthesized a type II heterojunction CdS/ZnO (CSZ) nanodispersion by means of one-pot precipitation. Different ... -
Photodegradable Antimicrobial Agents: Synthesis and Mechanism of Degradation
(Journal article; Peer reviewed, 2022)As a strategy to inactivate antimicrobial agents after use, we designed a range of ethanolamine derivatives where four of them possessed interesting activity. The ethanolamine moiety facilitates photodecomposition, which ... -
Relative Spatial Positions of Tryptophan and Cationic Residues in Helical Membrane-active Peptides Determine Their Cytotoxicity
(Journal article; Peer reviewed, 2012)The cytotoxic activity of 10 analogs of the idealized amphipathic helical 21-mer peptide (KAAKKAA)3, where three of the Ala residues at different positions have been replaced with Trp residues, has been investigated. The ... -
Application of Antisolvent Precipitation Method for Formulating Excipient-Free Nanoparticles of Psychotropic Drugs
(Journal article; Peer reviewed, 2022)The aim of the present study was to systematically examine the effects of variations in the process parameters of the antisolvent precipitation method employed in the preparation of excipient-free pure nanoparticles of ... -
A Scalable High-Yielding and Selective Oxidative Heck Cross-Coupling – A Key Step for the Synthesis of trans- Stilbenes
(Journal article; Peer reviewed, 2021)A selective oxidative Heck cross-coupling method was developed and optimized as a pivotal step for a synthetic route leading to the trans-stilbene framework. The developed method and synthesis were needed in a SAR study ... -
Short and Modular Synthesis of Substituted 2‑Aminopyrroles
(Journal article; Peer reviewed, 2021)We herein describe a simple and metal-free domino methodology to synthesize 2-aminopyrroles from alkynyl vinyl hydrazides. The domino reaction involves a novel propargylic 3,4-diaza-Cope rearrangement and a tandem ... -
Diels-Alder reactions with 1,1-diethoxybut-3-yn-2-one and some 1,1-diethoxy-5-hydroxyalk-3-yn-2-ones and their acetates
(Journal article; Peer reviewed, 2020) -
Membrane models for molecular simulations of peripheral membrane proteins
(Journal article; Peer reviewed, 2021)Peripheral membrane proteins (PMPs) bind temporarily to the surface of biological membranes. They also exist in a soluble form and their tertiary structure is often known. Yet, their membrane-bound form and their ...
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