Department of Chemistry
Nye registreringer
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Ruthenium-based antitumor drugs and delivery systems from monotherapy to combination therapy
(Journal article; Peer reviewed, 2022)Ruthenium complex is an important compound group for antitumor drug research and development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered clinical research. In recent years, the research on ruthenium ... -
Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation
(Journal article; Peer reviewed, 2022)Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP–/– mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen ... -
An NMR Study on Hydration and Molecular Interaction of Phytantriol‐Based Liquid Crystals
(Journal article; Peer reviewed, 2022-10-27)Phytantriol-based lyotropic liquid crystals (LLCs) have emerged as a new nanodrug delivery system. However, the understanding of phytantriol-based LLCs is lacking. In this study, we use NMR technology to characterize LLC ... -
An approach to assess and adjust for the influence of multicollinear covariates on metabolomics association patterns-applied to a study of the associations between a comprehensive lipoprotein profile and the homeostatic model assessment of insulin resistance
(Journal article; Peer reviewed, 2022)Introduction Comprehensive lipoprotein profiling using proton nuclear magnetic resonance (NMR) spectroscopy of serum represents an alternative to the homeostatic model assessment of insulin resistance (HOMA-IR). Both ... -
Investigating Ice Formation with NMR and Contact Angle Goniometry
(Master thesis, 2022-09-15)Ice formation on surfaces imposes numerous challenges in the industry and everyday life, ranging from icy windshields to airplanes needing de-icing before take-off. Today, the main methods to mitigate these issues revolve ... -
31P solid-state NMR on skeletal muscle of wild and farmed Atlantic salmon
(Journal article; Peer reviewed, 2022)Over the past 50 years, 31P NMR has proven a powerful tool for obtaining information on cellular biochemistry. Here we use this technique for the first time to study intracellular phosphorous metabolites in skeletal muscle ... -
Physical activity intensity profiles associated with cardiometabolic risk in middle-aged to older men and women
(Journal article; Peer reviewed, 2022)Accelerometers provide detailed data about physical activity (PA) across the full intensity spectrum. However, when examining associations with health, results are often aggregated to only a few summary measures [e.g. time ... -
Competition adsorption of malachite green and rhodamine B on polyethylene and polyvinyl chloride microplastics in aqueous environment
(Journal article; Peer reviewed, 2022)Microplastics (MPs) will cause compound pollution by combining with organic pollutants in the aqueous environment. It is important for environmental protection to study the adsorption mechanism of different MPs for pollutants. ... -
Selective Hydrodeoxygenation of Lignin-Derived Phenols to Aromatics Catalyzed by Nb2O5-Supported Iridium
(Journal article; Peer reviewed, 2022)The dominating catalytic approach to aromatic hydrocarbons from renewables, deoxygenation of phenol-rich depolymerized lignin bio-oils, is hard to achieve: Hydrodeoxygenation (HDO) of phenols typically leads to loss of ... -
Method development in analysis of cerium dioxide and titanium dioxide nanoparticles with sp-ICP-MS
(Master thesis, 2022-08-01)Denne oppgaven tar for seg analyse av ceriumdioksid og titandioksid ved hjelp av sp-ICP-MS i vann samt. biologiske matriser. En deloppgave er å utvikle en metode for å raffinere størrelsesfordelingen til nanosuspensjoner. -
Development and optimisation of processes for active pharmaceutical ingredients:A modern approach to the synthesis of the potent anti-leukaemia drug -Quinacrine
(Master thesis, 2022-08-15)The extensive testing and approval needed before a new active pharmaceutical can be used in treatments of patients has lead to an increased interest in drug repurposing of older approved drugs as treatments for other ... -
An environmentally benign and high-rate Appel type reaction
(Journal article; Peer reviewed, 2022)A high rate, selective, and productive Appel type reaction was developed. The method allows for ipso-substitution of the alcoholic hydroxy group with halogens ∈ [Cl, Br, I]. The method demands mild reaction conditions that ... -
Advancing quantification methods for polyphenols in brown seaweeds—applying a selective qNMR method compared with the TPC assay
(Journal article; Peer reviewed, 2022)Introduction Brown seaweeds are a sustainable biomass with a potential for various industrial applications. Polyphenols are an important contributor to this potential. Objective The aim was total quantification of ... -
Synthesis, Characterization and Catalytic Applications of N-Heterocyclic Carbene Based Vanadium Complexes.
(Master thesis, 2022-05-31)New tri- and tetradentate O-functionalized NHC oxo- and imido vanadium complexes have been synthesized and characterized. The complexes were preliminary tested for catalytic activity towards coupling of CO2 and epoxides ... -
Investigation of Adsorption Properties in the Metal-Organic Framework CPO-54-Ni
(Master thesis, 2022-06-01) -
Investigation of Gas Adsorption and Separation Properties in the Metal-Organic Framework CPO-54-Co
(Master thesis, 2022-06-01) -
Development, validation and application of in-silico methods to predict the macromolecular targets of small organic compounds
(Doctoral thesis, 2021-12-10)Computational methods to predict the macromolecular targets of small organic drugs and drug-like compounds play a key role in early drug discovery and drug repurposing efforts. These methods are developed by building ... -
Associations of lipoprotein particle profile and objectively measured physical activity and sedentary time in schoolchildren: a prospective cohort study
(Journal article; Peer reviewed, 2022-01-21)Background: Our understanding of the mechanisms through which physical activity might benefit lipoprotein metabolism is inadequate. Here we characterise the continuous associations between physical activity of different ... -
SuspensionFeeding Benthic Species’ Physiological and Microbiome Response to Salmon Farming and Associated Environmental Changes
(Journal article; Peer reviewed, 2022)Caged salmon farming is increasingly undertaken in water bodies with strong hydrodynamics where hard and mixed substrate habitats are more prevalent. Yet, these structurally complex and heterogeneous habitats support diverse ... -
Selective hydrodeoxygenation of phenolic compounds by oxide-supported iridium nanoparticles
(Master thesis, 2022-06-01)As more focus is placed on renewable energy to combat climate change and to meet the increasing energy demand, research into new energy sources has become more relevant than ever. A promising source of renewable energy as ...
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