Department of Chemistry
Nye registreringer
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Adapting CoRe and Storyline as tools to promote learning and coherence in a chemistry education course
(Research report, 2023) -
Biological Evaluations, NMR Analyses, Molecular Modeling Studies, and Overview of the Synthesis of the Marine Natural Product (−)-Mucosin
(Journal article; Peer reviewed, 2024)Natural products obtained from marine organisms continue to be a rich source of novel structural architecture and of importance in drug discovery, medicine, and health. However, the success of such endeavors depends on the ... -
Charge Transfer Quenching and Maximum of a Liquid-Air Contact Line Moving over a Hydrophobic Surface
(Journal article; Peer reviewed, 2024)Charge transfer when a hydrophobic fluoropolymer surface comes in contact with salt solutions of water, methanol, and glycerol is investigated. It is found that the charge transfer decreases faster with an increasing ... -
Biodistribution of Therapeutic Nanoparticles in Zebrafish Larvae
(Master thesis, 2024-06-03) -
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3
(Journal article; Peer reviewed, 2024)Using a combination of multisite λ−dynamics (MSλD) together with in vitro IC50 assays, we evaluated the polypharmacological potential of a scaffold currently in clinical trials for inhibition of human neutrophil elastase ... -
Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei
(Journal article; Peer reviewed, 2023)Microplastics (MPs) pose one of the major environmental threats to marine organisms and ecosystems on a global scale. Although many marine crustaceans are highly susceptible to MPs pollution, the toxicological effects and ... -
Discovery of polycyclic aromatic acid metabolites in fish exposed to the petroleum compounds 1-methylphenanthrene and 1,4-dimethylphenanthrene
(Journal article; Peer reviewed, 2024)Most of the polycyclic aromatic hydrocarbons (PAHs) in petroleum are alkylated (alkyl PAHs), still the metabolism of these alkyl PAHs to the expected acid products (polycyclic aromatic acids; PAAs) has yet to be demonstrated ... -
Photocontrol of the β-Hairpin Polypeptide Structure through an Optimized Azobenzene-Based Amino Acid Analogue
(Journal article; Peer reviewed, 2024)A family of neurodegenerative diseases, including Huntington’s disease (HD) and spinocerebellar ataxias, are associated with an abnormal polyglutamine (polyQ) expansion in mutant proteins that become prone to form amyloid-like ... -
Eukaryote-specific assembly factor DEAP2 mediates an early step of photosystem II assembly in Arabidopsis
(Journal article; Peer reviewed, 2023)The initial step of oxygenic photosynthesis is the thermodynamically challenging extraction of electrons from water and the release of molecular oxygen. This light-driven process, which is the basis for most life on Earth, ... -
Mechanistic Insights and Theory-Assisted Catalyst Development toward Kinetically E-Selective Olefin Metathesis
(Doctoral thesis, 2024-05-24)Olefinmetatese, en omordning av C=C-bindinger, har blitt en allsidig metodologi for å konstruere molekylære karbonrammer de siste 30 årene De fleste katalysatorene fokuserer på å konvertere lett tilgjengelige 1-alkener til ... -
Unlocking the potential of a lignocellulosic biorefinery : Optimizing yields of value-added furanic compounds in aqueous side streams from steam explosion and pellet production
(Doctoral thesis, 2024-04-23)Med en økende befolkning og en økende etterspørsel etter energi globalt, er vår avhengighet av fossile energikilder for å dekke våre energibehov blitt en betydelig utfordring på grunn av den begrensede tilgangen på disse ... -
Chemical studies of cytotoxic natural products from toxic and edible plant sources
(Doctoral thesis, 2024-04-19)Denne doktorgradsavhandlingen fokuserer på isolering og identifikasjon av naturstoffer fra fire utvalgte planter, hvor den cytotoksiske aktiviteten til nyoppdagede og interessante naturstoffer ble testet på blodkreftceller ... -
Keeping an “eye” on the experiment: computer vision for real-time monitoring and control
(Journal article; Peer reviewed, 2024)This work presents a generalizable computer vision (CV) and machine learning model that is used for automated real-time monitoring and control of a diverse array of workup processes. Our system simultaneously monitors ... -
Gas phase models of hydride transfer from divalent alkaline earth metals to CO2 and CH2O
(Journal article; Peer reviewed, 2023)The reactivity of HMg+, HMgCl, and HMgCl2− in hydride transfer reactions with CO2 and CH2O were studied by means of the reverse reactions—decarboxylation of HCO2MgCln+/0/− and deformylation of CH3OMgCln+/0/− (n = 0–2)—by ... -
Exploring hydrothermal liquefaction (HTL) of digested sewage sludge (DSS) at 5.3 L and 0.025 L bench scale using experimental design
(Journal article; Peer reviewed, 2023)A common perspective within the prospect of a greener future is utilising our waste materials. One waste material of which the world has abundant resources, and where we will keep having resources, is sewage sludge. This ... -
A reliable external calibration method for reaction monitoring with benchtop NMR
(Journal article; Peer reviewed, 2023)Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique with the ability to acquire both quantitative and structurally insightful data for multiple components in a test sample. This makes NMR ... -
Water-Accelerated Decomposition of Olefin Metathesis Catalysts
(Journal article; Peer reviewed, 2023)Water is ubiquitous in olefin metathesis, at levels ranging from contaminant to cosolvent. It is also non-benign. Water-promoted catalyst decomposition competes with metathesis, even for “robust” ruthenium catalysts. ... -
Leaflet Tensions Control the Spatio-Temporal Remodeling of Lipid Bilayers and Nanovesicles
(Journal article; Peer reviewed, 2023)Biological and biomimetic membranes are based on lipid bilayers, which consist of two monolayers or leaflets. To avoid bilayer edges, which form when the hydrophobic core of such a bilayer is exposed to the surrounding ... -
Cytotoxic Natural Products Isolated from Cryptogramma crispa (L.) R. Br.
(Journal article; Peer reviewed, 2023)Parsley fern, Cryptogramma crispa, is a common fern in arctic–alpine regions, and even though this species has been known since ancient times and has been presumed to cause the poisoning of horses, its natural products ... -
Toxicity prediction using target, interactome, and pathway profiles as descriptors
(Journal article; Peer reviewed, 2023)In silico methods are essential to the safety evaluation of chemicals. Computational risk assessment offers several approaches, with data science and knowledge-based methods becoming an increasingly important sub-group. ...