Browsing Department of Chemistry by Author "Aadland, Eivind"
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Accelerometer epoch setting is decisive for associations between physical activity and metabolic health in children
Aadland, Eivind; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Resaland, Geir Kåre; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2020)When analysing physical activity (PA) levels using accelerometry, the epoch setting is critical to capture intensity-specific PA correctly. The aim of the present study was to investigate the PA intensity signatures related ... -
Active Smarter Kids (ASK): Rationale and design of a cluster-randomized controlled trial investigating the effects of daily physical activity on children's academic performance and risk factors for non-communicable diseases
Resaland, Geir Kåre; Moe, Vegard Fusche; Aadland, Eivind; Steene-Johannessen, Jostein; Glosvik, Øyvind; Andersen, John Roger; Kvalheim, Olav Martin; McKay, Heather A.; Anderssen, Sigmund Alfred (Peer reviewed; Journal article, 2015-07-28)Background Evidence is emerging from school-based studies that physical activity might favorably affect children’s academic performance. However, there is a need for high-quality studies to support this. Therefore, the ... -
Aerobic fitness and metabolic health in children: A clinical validation of directly measured maximal oxygen consumption versus performance measures as markers of health
Aadland, Eivind; Kvalheim, Olav Martin; Rajalahti, Tarja; Skrede, Turid; Resaland, Geir Kåre (Peer reviewed; Journal article, 2017-09)High aerobic fitness is consistently associated with a favorable metabolic health profile in children. However, measurement of oxygen uptake, regarded as the gold standard for evaluating aerobic fitness, is often not ... -
An approach to assess and adjust for the influence of multicollinear covariates on metabolomics association patterns-applied to a study of the associations between a comprehensive lipoprotein profile and the homeostatic model assessment of insulin resistance
Kvalheim, Olav Martin; Rajalahti, Tarja; Aadland, Eivind (Journal article; Peer reviewed, 2022)Introduction Comprehensive lipoprotein profiling using proton nuclear magnetic resonance (NMR) spectroscopy of serum represents an alternative to the homeostatic model assessment of insulin resistance (HOMA-IR). Both ... -
Associations of lipoprotein particle profile and objectively measured physical activity and sedentary time in schoolchildren: a prospective cohort study
Jones, Paul Remy; Rajalahti, Tarja; Resaland, Geir Kåre; Aadland, Eivind; Steene-Johannessen, Jostein; Anderssen, Sigmund Alfred; Bathen, Tone Frost; Andreassen, Trygve; Kvalheim, Olav Martin; Ekelund, Ulf (Journal article; Peer reviewed, 2022-01-21)Background: Our understanding of the mechanisms through which physical activity might benefit lipoprotein metabolism is inadequate. Here we characterise the continuous associations between physical activity of different ... -
Associations of physical activity and sedentary time with lipoprotein subclasses in Norwegian schoolchildren: The Active Smarter Kids (ASK) study
Jones, Paul Remy; Rajalahti, Tarja; Resaland, Geir Kåre; Aadland, Eivind; Steene-Johannessen, Jostein; Anderssen, Sigmund Alfred; Bathen, Tone Frost; Andreassen, Trygve; Kvalheim, Olav Martin; Ekelund, Ulf (Journal article; Peer reviewed, 2019)Background and aims: Physical activity is favourably associated with certain markers of lipid metabolism. The relationship of physical activity with lipoprotein particle profiles in children is not known. Here we examine ... -
Associations of volumes and patterns of physical activity with metabolic health in children: A multivariate pattern analysis approach
Aadland, Eivind; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Resaland, Geir Kåre; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2018)Physical activity (PA) favorably affects metabolic health in children, but it is unclear how total volumes versus patterns (bouts and breaks) of PA relate to health. By means of multivariate pattern analysis that can handle ... -
Cardiometabolic associations between physical activity, adiposity, and lipoprotein subclasses in prepubertal norwegian children
Rajalahti, Tarja; Aadland, Eivind; Resaland, Geir Kåre; Anderssen, Sigmund Alfred; Kvalheim, Olav Martin (Journal article; Peer reviewed, 2021)Lipoprotein subclasses possess crucial cardiometabolic information. Due to strong multicollinearity among variables, little is known about the strength of influence of physical activity (PA) and adiposity upon this ... -
A comparison of analytical approaches to investigate associations for accelerometry-derived physical activity spectra with health and developmental outcomes in children
Aadland, Eivind; Nilsen, Ada Kristine Ofrim; Andersen, Lars Bo; Rowlands, Alex V.; Kvalheim, Olav Martin (Journal article; Peer reviewed, 2021)The use of high-resolution physical activity intensity spectra obtained from accelerometry can improve knowledge of associations with health and development beyond the use of traditional summary measures of intensity. The ... -
Cross-sectional and prospective associations between aerobic fitness and lipoprotein particle profile in a cohort of Norwegian schoolchildren
Jones, Paul Remy; Rajalahti, Tarja; Resaland, Geir Kåre; Aadland, Eivind; Steene-Johannessen, Jostein; Anderssen, Sigmund Alfred; Bathen, Tone Frost; Andreassen, Trygve; Kvalheim, Olav Martin; Ekelund, Ulf (Journal article; Peer reviewed, 2021)Background and aims The associations between aerobic fitness and traditional measures of lipid metabolism in children are uncertain. We investigated whether higher levels of aerobic fitness benefit lipoprotein metabolism ... -
Effects of physical activity on schoolchildren's academic performance: The Active Smarter Kids (ASK) cluster-randomized controlled trial
Resaland, Geir Kåre; Aadland, Eivind; Moe, Vegard Fusche; Aadland, Katrine Nyvoll; Skrede, Turid; Stavnsbo, Mette; Suominen, Laura; Steene-Johannessen, Jostein; Glosvik, Øyvind; Andersen, John Roger; Kvalheim, Olav Martin; Engelsrud, Gunn; Andersen, Lars Bo; Holme, Ingar Morten K; Ommundsen, Yngvar; Kriemler, Susi; van Mechelen, Willem; McKay, Heather A.; Ekelund, Ulf; Anderssen, Sigmund Alfred (Peer reviewed; Journal article, 2016-10)Objective. To investigate the effect of a seven-month, school-based cluster-randomized controlled trial on academic performance in 10-year-old children. Methods. In total, 1129 fifth-grade children from 57 elementary schools ... -
GRANADA consensus on analytical approaches to assess associations with accelerometer-determined physical behaviours (physical activity, sedentary behaviour and sleep) in epidemiological studies
Migueles, Jairo H.; Aadland, Eivind; Andersen, Lars Bo; Brønd, Jan Christian; Chastin, Sebastien; Hansen, Bjørge Hermann; Konstabel, Kenn; Kvalheim, Olav Martin; McGregor, Duncan E.; Rowlands, Alex V.; Sabia, Séverine; van Hees, Vincent T.; Walmsley, Rosemary; Ortega, Francisco B. (Journal article; Peer reviewed, 2021)The inter-relationship between physical activity, sedentary behaviour and sleep (collectively defined as physical behaviours) is of interest to researchers from different fields. Each of these physical behaviours has been ... -
Influence of adiposity and physical activity on the cardiometabolic association pattern of lipoprotein subclasses to aerobic fitness in prepubertal children
Rajalahti, Tarja; Aadland, Eivind; Resaland, Geir Kåre; Anderssen, Sigmund Alfred; Kvalheim, Olav Martin (Journal article; Peer reviewed, 2021)Aerobic fitness (AF) and lipoprotein subclasses associate to each other and to cardiovascular health. Adiposity and physical activity (PA) influence the association pattern of AF to lipoproteins almost inversely making it ... -
Interpretation of associations between the accelerometry physical activity spectrum and cardiometabolic health and locomotor skills in two cohorts of children using raw, log-transformed, or compositional data
Aadland, Eivind; Andersen, Lars Bo; Migueles, Jairo Hidalgo; Ortega, Francisco B.; Kvalheim, Olav Martin (Journal article; Peer reviewed, 2020)It is discussed whether associations between accelerometer-derived physical activity intensities and outcomes should be analysed as absolute or relative data. The aim of the present study was to compare interpretation of ... -
Interpretation of multivariate association patterns between multicollinear physical activity accelerometry data and cardiometabolic health in children-a tutorial
Aadland, Eivind; Andersen, Lars Bo; Resaland, Geir Kåre; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2019-07-02)Associations between multicollinear accelerometry-derived physical activity (PA) data and cardiometabolic health in children needs to be analyzed using an approach that can handle collinearity among the explanatory variables. ... -
Multicollinear physical activity accelerometry data and associations to cardiometabolic health: Challenges, pitfalls, and potential solutions
Aadland, Eivind; Kvalheim, Olav Martin; Anderssen, Sigmund Alfred; Resaland, Geir Kåre; Andersen, Lars Bo (Peer reviewed; Journal article, 2019-08-27)Background: The analysis of associations between accelerometer-derived physical activity (PA) intensities and cardiometabolic health is a major challenge due to multicollinearity between the explanatory variables. This ... -
The multivariate physical activity signature associated with metabolic health in children
Aadland, Eivind; Kvalheim, Olav Martin; Anderssen, Sigmund Alfred; Resaland, Geir Kåre; Andersen, Lars Bo (Peer reviewed; Journal article, 2018-08-15)Background. Physical activity is a cornerstone for promoting good metabolic health in children, but it is heavily debated which intensities (including sedentary time) are most influential. A fundamental limitation to current ... -
The multivariate physical activity signature associated with metabolic health in children and youth: An International Children's Accelerometry Database (ICAD) analysis
Aadland, Eivind; Kvalheim, Olav Martin; Hansen, Bjørge Hermann; Kriemler, Susi; Ried-Larsen, Mathias; Wedderkopp, Niels; Sardinha, Luis B.; Møller, Niels Christian; Hallal, Pedro C.; Anderssen, Sigmund Alfred; Northstone, Kate; Andersen, Lars Bo (Journal article; Peer reviewed, 2020)There is solid evidence for an association between physical activity and metabolic health outcomes in children and youth, but for methodological reasons most studies describe the intensity spectrum using only a few summary ... -
Physical activity intensity profiles associated with cardiometabolic risk in middle-aged to older men and women
Dempsey, Paddy C.; Aadland, Eivind; Strain, Tessa; Kvalheim, Olav Martin; Westgate, Kate; Lindsay, Tim; Khaw, Kay-Tee; Wareham, Nicholas J.; Brage, Søren Karl; Wijndaele, Katrien (Journal article; Peer reviewed, 2022)Accelerometers provide detailed data about physical activity (PA) across the full intensity spectrum. However, when examining associations with health, results are often aggregated to only a few summary measures [e.g. time ...